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GO:0003918: DNA topoisomerase type II (ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192]


There are 213 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Sequences (213) (download table)

InterPro Domains

GO Terms

Family Terms