GO:0004663: Rab geranylgeranyltransferase activity (Molecular function)

"Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family." [EC:2.5.1.60, GOC:mah, PMID:8621375]


There are 205 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_42 Plasmodium berghei ANKA 2.74 % 0.000609 0.016658
Sequences (205) (download table)

InterPro Domains

GO Terms

Family Terms