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GO:0005852: eukaryotic translation initiation factor 3 complex (Cellular component)

"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]


There are 375 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_4 Plasmodium berghei ANKA 2.4 % 0.001104 0.009485
Cluster_36 Plasmodium berghei ANKA 4.84 % 0.000139 0.000797
Cluster_38 Plasmodium falciparum 3D7 4.94 % 5e-06 0.003058
Sequences (375) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms