Heatmap: Cluster_48 (P. berghei)

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Gene
Asexual: SRP099925
Asexual, PbSR-MG KO: SRP109709
10 hpi, ab libitum: SRP059210
10 hpi, diet restriction: SRP059210
10 hpi, ab libitum, kin KO: SRP059210
10 hpi, diet restriction, kin KO: SRP059210
16 hpi, WT: ERP004868
16 hpi, CL: ERP004868
Trophozoite, 16 hpi: SRP027529
Schizont, predicted: ERP021229
Schizont, WT: SRP073801
Schizont, 22 hpi: SRP027529
Schizont: ERP004598
Schizont, ap2-g KO: SRP073801
Schizont, ap2-g2 KO: SRP073801
Schizont, ap2-l KO: SRP073801
Schizont, ap2-o KO: SRP073801
Schizont, ap2-o2 KO: SRP073801
Schizont, ap2-o3 KO: SRP073801
Schizont, ap2-o4 KO: SRP073801
Schizont, ap2-sp KO: SRP073801
Schizont, ap2-sp2 KO: SRP073801
Schizont, ap2-sp3 KO: SRP073801
Schizont, PBANKA_131970 KO: SRP073801
Schizont, ppm2 KO: ERP004598
Schizont, ppm5 KO: ERP004598
Gametocyte, WT: SRP073801
Gametocyte: SRP027529
Gametocyte: ERP004598
Gametocyte (male): SRP099925
Gametocyte (female): SRP099925
Gametocyte ap2-o KO: SRP073801
Gametocyte ap2-o2 KO: SRP073801
Gametocyte ap2-o3 KO: SRP073801
Gametocyte, ppm5 KO: ERP004598
Gametocyte (male), PbSR-MG KO: SRP109709
Gametocyte (female), PbSR-MG KO: SRP109709
Ookinete, WT: SRP073801
Ookinete, WT: ERP004740
Ookinete ap2-o KO: SRP073801
Ookinete ap2-o2 KO: SRP073801
Ookinete ap2-o3 KO: SRP073801
Ookinete, mutant: ERP004740
51.32 57.91 49.42 30.61 37.68 20.09 38.78 29.45 79.18 0.0 100.5 149.67 52.2 63.03 81.0 104.1 74.04 80.57 58.27 113.64 90.3 122.36 106.81 104.44 48.12 58.39 27.88 44.83 30.99 101.22 45.01 32.68 53.51 42.02 40.89 150.21 27.67 63.54 45.45 64.42 59.77 35.78 48.27
19.54 12.92 11.54 32.06 5.13 8.79 156.5 143.34 22.11 0.0 172.63 467.14 262.4 134.68 144.05 269.54 235.76 92.87 95.2 722.68 182.97 306.11 278.67 347.81 399.46 271.79 10.65 16.46 18.3 33.45 7.28 12.74 13.41 22.07 28.28 18.05 7.46 125.66 169.81 82.2 133.83 130.15 99.4
14.64 9.69 10.65 12.03 5.65 2.43 21.5 24.66 4.38 0.0 133.23 368.45 77.03 108.46 175.34 114.77 109.2 100.12 111.82 138.39 104.72 169.34 163.7 158.69 99.87 82.82 6.12 11.28 10.02 7.32 5.57 8.16 4.32 4.23 11.13 4.87 6.61 35.86 16.38 61.49 47.97 51.69 6.85
126.65 128.62 130.53 80.31 66.82 40.03 86.92 327.91 78.1 0.0 489.91 940.41 475.3 326.9 419.87 545.84 463.12 360.03 436.03 680.6 466.88 720.43 683.13 771.09 655.71 441.67 309.86 161.47 185.84 496.42 220.79 427.45 415.82 419.71 217.01 623.08 98.5 145.95 59.6 260.06 272.38 137.59 19.84
47.59 43.98 59.95 39.74 30.99 16.59 31.21 47.46 41.56 0.0 176.76 286.37 108.89 60.54 98.48 149.05 110.21 141.69 134.88 216.2 162.69 177.76 174.32 180.72 124.13 117.15 177.28 71.59 83.67 228.11 87.81 273.54 255.48 288.13 98.56 270.52 32.41 87.17 30.6 152.01 133.89 108.05 15.75
23.95 10.61 23.09 51.95 9.06 5.83 21.13 38.99 0.73 0.0 482.15 839.9 420.86 508.51 588.65 500.43 561.94 326.78 472.86 726.95 378.14 626.4 580.25 629.99 595.11 352.96 20.61 29.78 48.63 36.23 8.65 21.82 9.93 10.28 44.43 16.09 10.41 36.5 12.2 115.31 72.26 46.37 5.6
9.83 6.05 7.32 40.06 3.23 4.52 5.76 10.68 8.04 0.0 175.68 66.06 140.98 223.65 164.39 172.53 403.8 132.57 177.41 292.78 125.98 200.75 177.77 262.83 124.72 86.06 2.39 6.77 9.43 9.28 1.41 3.91 4.61 6.16 8.48 3.17 0.76 18.2 5.6 39.27 31.02 15.07 4.51
65.48 72.75 81.61 40.79 60.43 36.47 77.89 185.45 83.05 0.0 153.98 253.66 171.94 121.41 213.54 160.65 179.64 131.56 157.99 165.2 223.96 184.04 184.47 169.53 196.35 153.38 150.1 243.71 178.31 200.02 152.84 231.53 150.76 205.12 180.59 229.71 118.44 79.29 65.7 161.8 102.49 90.74 42.19
2.39 1.05 4.29 19.36 3.8 2.48 27.96 46.49 9.31 0.0 181.89 346.61 87.22 130.86 128.29 245.5 220.33 110.24 117.27 444.69 279.01 354.3 330.03 358.63 105.46 69.88 195.33 110.64 45.47 8.07 51.46 125.56 85.79 107.71 47.55 4.88 79.97 67.17 17.34 88.35 50.82 102.66 20.22
26.12 24.92 26.83 14.89 7.75 4.26 9.42 11.93 28.12 0.0 162.23 351.17 51.68 68.66 95.4 165.86 95.64 112.61 104.54 166.99 157.62 166.52 166.55 176.15 68.93 60.27 125.34 104.78 27.3 153.52 60.77 114.4 192.95 175.96 45.79 192.04 11.32 55.02 4.42 86.0 105.43 57.1 2.27
26.19 9.6 32.99 191.53 11.3 10.94 38.4 51.9 10.95 262.25 1075.14 2924.39 1145.5 1074.57 1244.41 1034.56 1465.66 596.65 1187.88 2376.8 798.29 1520.09 1553.17 1809.85 1581.71 824.15 76.9 67.86 121.2 63.32 19.98 77.65 63.63 21.53 72.51 26.98 21.64 40.31 28.48 82.77 114.51 32.74 10.48
14.29 10.31 11.74 14.36 6.47 6.6 29.22 43.84 14.31 0.0 134.06 278.61 129.9 73.4 109.28 165.5 109.34 55.21 73.94 252.41 222.68 222.95 216.63 220.31 178.88 113.26 107.3 117.13 77.79 77.55 74.86 98.46 79.22 106.62 81.66 59.64 84.86 53.12 31.62 58.76 42.94 57.65 16.43
126.79 112.7 198.19 224.6 116.0 129.09 60.46 92.28 94.56 2.59 262.47 195.69 110.22 190.44 217.07 223.75 241.29 249.69 271.38 283.67 243.2 217.98 219.37 233.32 136.46 127.58 266.55 171.69 76.54 414.18 170.55 284.99 406.92 401.91 132.23 420.74 76.48 177.13 49.79 220.21 251.49 187.82 48.25
51.14 36.91 106.1 65.89 53.37 27.07 50.9 56.32 57.69 0.0 245.95 496.81 100.79 109.59 158.25 297.48 175.44 133.4 120.22 374.75 321.23 417.97 385.45 382.3 131.61 113.58 96.7 83.92 31.44 155.27 77.15 104.52 132.85 142.06 63.75 213.95 33.84 99.37 39.77 99.52 144.0 129.87 24.4
7.15 9.12 14.23 13.16 7.67 4.04 1.91 3.71 10.58 0.0 111.25 77.68 83.52 93.33 109.22 95.98 109.29 57.49 67.98 206.06 71.09 113.98 107.72 126.0 109.61 61.04 7.62 9.43 10.06 8.18 2.5 10.38 12.91 12.78 10.44 6.24 3.08 12.63 1.81 22.12 43.39 15.75 1.4
9.97 5.44 11.08 47.85 2.81 5.81 33.75 51.84 20.62 0.0 309.37 608.67 223.15 371.89 364.36 277.17 419.05 227.09 346.49 623.75 230.78 384.13 386.82 491.66 384.85 170.47 27.16 43.1 31.58 55.98 16.85 27.86 38.38 36.92 26.41 52.13 5.85 51.86 30.32 83.23 84.84 36.2 10.2
2.38 2.22 8.85 38.48 5.11 4.69 2.25 3.08 8.46 0.0 308.68 248.39 133.28 544.49 315.76 195.09 493.6 221.44 416.33 472.0 197.97 262.05 285.74 343.81 157.8 75.17 19.23 22.61 11.97 14.66 7.48 25.34 58.9 19.9 9.59 11.72 7.28 13.56 1.85 32.77 72.14 7.22 0.62
PBANKA_1101400 (RAP2/3)
48.74 15.95 35.9 146.19 21.56 30.24 47.85 62.9 6.82 0.0 993.33 2528.73 1076.7 643.2 859.74 1331.1 1226.58 439.45 539.66 2354.19 1160.45 1969.74 1858.57 1849.95 1466.0 991.09 238.59 213.29 206.57 228.81 212.86 180.39 146.6 201.71 221.76 158.06 229.29 54.44 25.33 42.45 84.41 84.61 23.88
25.1 21.83 20.5 10.03 14.65 7.93 35.37 82.57 29.37 0.0 71.11 154.52 52.51 29.95 112.02 81.2 75.39 55.0 49.89 89.31 183.17 107.15 116.32 97.01 54.3 57.83 115.0 162.41 78.15 69.85 97.76 125.45 112.48 119.46 102.75 104.33 120.39 71.87 48.81 104.19 78.21 99.52 15.39
59.59 53.87 87.87 78.34 55.9 45.67 37.69 63.06 72.67 0.0 259.49 343.06 138.16 165.02 237.45 234.17 182.55 212.55 208.48 227.91 178.5 293.04 252.44 279.81 168.04 159.53 81.22 56.45 48.19 33.5 42.01 67.32 56.1 54.33 62.15 27.62 48.72 47.23 24.86 108.94 80.86 66.66 13.21
16.37 7.02 15.45 61.42 6.27 8.08 44.27 57.76 15.72 0.0 453.19 930.42 374.98 456.75 494.66 502.96 699.6 292.5 486.72 885.34 421.31 633.31 633.83 722.44 497.92 323.2 133.36 79.76 84.01 34.71 54.58 111.89 39.62 73.89 59.71 21.42 72.8 60.77 40.78 103.68 63.54 71.08 22.07
20.39 20.2 40.44 33.33 24.26 14.62 17.93 12.09 29.38 0.0 105.69 58.81 56.84 106.39 100.94 107.42 159.68 79.71 83.63 204.57 82.27 130.28 125.72 155.74 69.11 43.02 5.22 6.42 5.54 10.17 2.8 5.89 22.52 8.31 8.6 6.63 2.44 44.1 29.78 41.02 91.91 28.3 7.91
12.74 6.21 9.51 15.4 5.07 2.02 19.04 50.07 2.93 0.0 179.34 383.0 175.7 160.19 216.54 246.49 179.46 101.37 173.07 310.65 195.93 277.52 260.54 259.08 203.72 187.88 38.8 25.65 24.08 189.38 56.46 69.86 66.17 185.25 38.79 172.75 9.27 44.21 14.1 38.46 43.88 102.02 7.84
12.28 12.89 18.16 9.19 14.51 9.53 18.72 16.87 15.21 0.0 33.49 43.6 27.35 9.54 27.19 49.35 19.99 26.25 17.14 47.63 86.54 58.09 63.83 53.63 24.26 29.11 79.52 88.45 48.39 9.96 46.19 74.79 43.55 33.23 55.24 10.3 71.98 30.21 19.56 45.5 51.48 32.22 10.74
13.32 14.26 19.87 13.89 10.33 4.14 2.21 4.4 31.78 0.0 85.86 181.56 48.27 47.98 105.16 87.96 55.8 49.48 66.09 113.46 83.92 119.19 118.0 116.36 73.44 42.8 12.42 33.87 10.74 25.96 12.72 18.49 30.86 24.34 13.6 24.76 8.38 10.62 1.97 20.31 48.19 10.07 0.73
17.76 11.31 9.08 8.1 6.33 5.48 194.77 174.93 9.13 0.0 47.57 158.55 92.2 20.83 38.33 72.82 41.22 25.26 28.8 107.34 142.17 105.05 112.29 103.95 97.38 85.87 113.03 165.15 119.38 61.75 119.05 126.31 148.48 80.35 98.26 79.28 134.21 110.17 165.02 168.07 91.16 73.33 91.63
16.73 10.52 15.04 45.09 9.67 6.08 3.96 1.24 24.29 0.27 362.02 713.74 334.78 326.41 368.35 324.82 354.81 188.48 204.05 622.55 339.14 512.62 518.65 573.21 449.85 210.11 21.89 40.23 29.01 73.45 26.53 34.17 53.13 47.14 27.21 103.25 9.49 17.55 3.12 27.72 55.83 14.81 1.06
6.8 5.42 12.51 13.04 5.74 3.25 1.14 1.5 3.52 0.0 70.66 108.94 29.56 39.46 68.74 55.67 38.86 44.74 48.98 59.56 46.66 76.02 79.52 88.88 38.95 26.42 4.73 9.63 5.23 6.46 3.15 8.98 11.28 8.68 6.05 8.45 2.86 5.1 0.91 20.76 16.14 3.9 0.37
3.29 3.2 3.18 3.93 1.2 0.54 11.95 17.01 4.15 0.0 37.41 79.21 25.65 17.17 24.46 58.13 30.14 13.9 18.93 86.61 56.17 80.46 70.46 67.37 29.87 26.27 30.56 27.04 7.76 18.84 17.78 20.62 30.33 13.92 13.82 23.25 17.16 17.04 9.7 27.49 29.28 20.79 8.99
82.51 75.5 62.26 50.66 34.53 27.46 119.84 163.92 49.56 0.0 204.31 457.89 241.41 68.42 93.06 269.69 108.86 89.45 88.58 259.33 370.98 352.81 345.44 334.31 287.51 252.97 271.91 241.04 222.46 59.97 205.5 220.32 239.89 236.48 219.74 44.49 249.56 110.45 101.12 97.49 96.61 165.11 47.09
58.0 45.89 47.31 52.2 31.55 12.76 41.48 43.63 30.31 0.0 254.36 541.94 292.69 222.74 209.78 321.56 319.23 137.22 133.96 549.52 370.34 468.84 475.3 461.34 427.8 262.42 229.98 272.7 172.06 36.65 128.73 166.35 65.43 10.5 148.12 27.45 150.93 39.14 34.56 80.03 65.32 25.74 15.68
79.06 76.29 77.66 55.89 42.4 21.01 14.65 17.79 58.69 0.0 189.77 255.05 122.22 74.13 136.99 173.47 145.26 166.84 172.99 211.96 201.71 239.15 240.93 245.1 139.26 128.68 168.46 98.55 89.31 278.11 134.06 238.29 272.06 304.68 114.65 387.91 48.1 58.03 15.72 122.92 122.41 70.08 5.07
9.66 8.28 13.66 21.92 10.06 3.54 21.99 30.17 10.46 0.0 91.63 177.28 67.42 78.37 92.98 94.03 104.09 41.31 61.13 189.1 89.44 118.8 134.66 148.54 81.74 44.08 20.35 43.64 15.08 22.28 18.95 30.9 33.61 36.7 15.39 37.05 14.28 25.0 36.9 74.29 39.88 12.89 10.09
16.24 12.93 33.93 29.14 16.17 11.14 19.83 32.65 24.26 43.38 91.37 192.78 88.28 110.87 144.77 84.74 152.71 73.7 97.13 178.15 80.62 134.96 145.05 151.95 114.35 66.24 11.07 13.62 11.65 9.78 4.51 11.19 9.37 9.07 10.6 5.75 5.38 22.14 14.43 35.58 33.66 23.75 4.83
6.81 3.28 17.15 20.92 9.26 5.79 21.56 32.52 3.62 0.0 136.33 160.84 49.05 106.69 99.02 144.79 161.14 76.73 122.19 305.93 150.5 156.94 165.6 189.28 76.46 45.79 122.82 57.14 13.71 123.08 48.3 148.0 193.01 197.39 25.36 155.52 10.64 55.22 19.78 76.71 82.87 60.41 11.15
2.52 1.35 5.47 8.16 2.68 1.44 1.89 3.1 1.3 0.0 65.44 146.11 21.97 54.66 71.73 64.33 79.4 45.41 42.68 104.95 68.65 113.74 118.63 136.04 36.17 20.02 4.77 4.87 2.4 5.99 1.74 7.17 7.82 10.23 2.87 5.63 0.55 7.27 1.64 12.07 20.58 8.57 1.23
14.62 11.34 16.17 35.31 10.45 7.22 3.42 5.35 6.98 0.0 235.35 560.06 141.03 233.47 328.04 247.29 351.82 161.48 146.11 466.05 221.8 352.1 353.48 392.31 216.37 112.58 46.59 33.98 27.16 94.4 33.78 59.57 108.74 86.45 30.89 117.32 5.98 16.72 2.79 25.03 83.71 14.14 1.02
8.83 10.97 12.36 19.27 7.75 5.49 18.43 25.28 14.08 0.0 133.39 179.16 86.85 72.97 92.08 216.54 118.62 66.34 75.76 254.99 154.74 243.23 236.99 254.22 106.0 84.55 74.47 30.19 16.8 22.21 14.65 110.92 108.33 74.48 19.65 20.82 14.62 37.71 10.21 61.94 41.67 18.32 13.21
148.21 125.53 182.36 104.32 88.54 50.99 140.56 176.03 84.92 0.0 520.59 995.95 409.01 209.69 380.63 467.53 311.6 374.59 430.8 509.36 487.25 659.32 634.61 629.57 536.36 426.7 345.94 215.0 229.63 492.41 248.73 504.25 484.89 600.64 279.09 580.4 106.69 232.12 114.98 452.43 317.32 220.7 44.21
3.64 4.32 2.99 1.43 3.29 1.34 32.29 65.74 4.25 0.0 39.25 30.09 38.89 9.69 32.17 55.93 11.0 15.5 14.55 38.6 59.79 62.18 50.15 45.79 29.61 40.29 50.72 39.21 50.68 18.1 34.28 42.42 32.9 39.63 49.61 40.27 46.94 29.72 23.87 42.5 23.17 37.6 9.0
54.25 44.98 79.85 80.09 42.97 33.89 108.83 110.6 62.96 0.0 113.88 207.25 79.15 49.84 92.76 161.69 81.0 63.85 64.73 175.62 155.47 237.21 224.13 219.76 110.02 85.59 55.03 50.78 28.32 59.62 38.33 64.07 69.41 74.83 39.04 68.76 32.91 106.57 94.99 129.4 108.81 68.18 68.81
10.88 7.28 8.21 16.96 4.42 1.88 33.53 51.04 11.63 0.0 108.78 200.88 115.3 78.3 86.02 129.49 102.12 44.11 64.87 191.16 115.6 157.92 153.07 163.62 127.19 97.33 31.64 35.56 28.84 17.59 25.28 28.37 24.21 24.22 35.2 16.02 28.64 42.89 23.55 65.8 54.92 49.64 11.44
4.89 3.35 10.9 16.76 5.28 3.04 10.71 12.13 2.27 0.0 119.78 259.85 63.69 103.25 197.22 124.38 117.26 60.36 73.41 240.5 121.36 181.98 200.29 222.55 90.76 52.91 23.2 41.2 13.21 7.32 15.47 28.47 43.43 7.51 17.56 7.09 22.73 26.79 23.23 73.3 47.71 10.06 6.1

Details

Raw expression values (TPM normalized), Green cells indicate low expression and red high. (Dark gray cells indicate missing values)