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Heatmap: Cluster_28 (P. berghei)

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Gene
Asexual: SRP099925
Asexual, PbSR-MG KO: SRP109709
10 hpi, ab libitum: SRP059210
10 hpi, diet restriction: SRP059210
10 hpi, ab libitum, kin KO: SRP059210
10 hpi, diet restriction, kin KO: SRP059210
16 hpi, WT: ERP004868
16 hpi, CL: ERP004868
Trophozoite, 16 hpi: SRP027529
Schizont, predicted: ERP021229
Schizont, WT: SRP073801
Schizont, 22 hpi: SRP027529
Schizont: ERP004598
Schizont, ap2-g KO: SRP073801
Schizont, ap2-g2 KO: SRP073801
Schizont, ap2-l KO: SRP073801
Schizont, ap2-o KO: SRP073801
Schizont, ap2-o2 KO: SRP073801
Schizont, ap2-o3 KO: SRP073801
Schizont, ap2-o4 KO: SRP073801
Schizont, ap2-sp KO: SRP073801
Schizont, ap2-sp2 KO: SRP073801
Schizont, ap2-sp3 KO: SRP073801
Schizont, PBANKA_131970 KO: SRP073801
Schizont, ppm2 KO: ERP004598
Schizont, ppm5 KO: ERP004598
Gametocyte, WT: SRP073801
Gametocyte: SRP027529
Gametocyte: ERP004598
Gametocyte (male): SRP099925
Gametocyte (female): SRP099925
Gametocyte ap2-o KO: SRP073801
Gametocyte ap2-o2 KO: SRP073801
Gametocyte ap2-o3 KO: SRP073801
Gametocyte, ppm5 KO: ERP004598
Gametocyte (male), PbSR-MG KO: SRP109709
Gametocyte (female), PbSR-MG KO: SRP109709
Ookinete, WT: SRP073801
Ookinete, WT: ERP004740
Ookinete ap2-o KO: SRP073801
Ookinete ap2-o2 KO: SRP073801
Ookinete ap2-o3 KO: SRP073801
Ookinete, mutant: ERP004740
5.1 2.73 28.58 18.55 23.8 9.74 30.13 22.18 22.95 0.0 113.01 84.6 4.73 33.8 52.29 121.74 95.93 81.37 69.3 130.24 306.83 115.57 141.03 119.58 4.49 7.38 413.81 136.86 7.34 1.74 5.69 230.72 277.26 259.56 12.6 1.29 9.05 185.33 17.7 97.31 207.74 260.24 10.3
17.38 21.2 19.47 7.37 33.69 11.48 367.85 465.12 37.55 0.0 189.51 65.31 315.43 12.21 65.99 238.33 180.43 111.98 179.73 182.25 837.37 212.93 333.08 198.43 207.19 376.23 1621.1 2375.48 900.5 134.83 1069.84 1217.79 1089.39 1344.27 1047.16 139.51 1911.89 782.1 465.84 269.96 657.98 1221.13 344.31
8.55 8.61 8.81 4.75 6.33 4.0 19.95 17.74 12.6 0.0 23.53 12.09 5.19 8.36 22.28 32.62 15.69 15.44 14.68 21.94 45.67 34.93 31.86 28.5 1.97 6.85 90.59 49.91 5.67 11.11 11.38 72.09 57.78 69.6 14.85 15.58 17.9 37.18 11.38 45.19 38.5 71.3 7.68
15.48 14.27 54.65 38.05 28.88 23.36 32.42 49.31 39.45 6.09 74.44 55.4 20.16 32.2 58.07 60.35 51.94 85.07 67.4 51.97 69.21 71.17 66.63 68.23 16.16 24.39 85.09 40.91 29.07 13.66 17.28 91.74 52.66 81.97 30.48 13.45 20.29 58.25 22.69 71.86 79.97 71.03 14.52
94.38 97.21 97.6 103.13 38.89 60.08 119.83 148.95 213.38 0.0 229.43 285.18 106.72 95.5 135.16 216.9 119.5 198.88 227.62 220.01 302.33 202.54 226.17 230.02 94.91 121.66 457.7 427.82 252.35 107.94 159.98 258.42 414.69 358.61 196.59 104.02 186.58 292.65 48.28 457.34 330.69 361.89 28.5
35.69 34.23 68.36 47.32 43.0 34.8 69.69 49.28 48.91 0.0 58.3 33.13 29.32 10.52 36.64 81.19 42.75 61.11 51.3 69.94 127.54 86.64 109.32 97.73 20.12 40.91 136.49 67.27 17.92 23.04 42.26 136.47 121.09 114.24 52.22 19.77 55.15 97.7 35.04 197.66 100.99 68.92 17.11
23.07 21.18 64.09 50.91 52.28 35.14 36.02 86.77 38.23 0.0 45.39 13.28 37.08 5.53 10.04 61.18 33.63 43.15 26.26 39.16 164.3 49.99 62.17 45.77 21.92 48.77 271.06 192.84 64.58 20.33 154.57 196.01 205.34 106.97 111.35 28.86 213.68 126.1 33.9 54.35 101.88 155.98 15.69
19.92 16.5 22.01 29.34 19.83 19.05 46.83 44.68 40.98 0.0 25.53 13.7 11.43 3.19 9.14 32.13 8.82 25.32 16.88 20.37 29.34 25.6 28.11 30.66 9.05 13.52 87.03 52.12 25.04 23.91 17.51 70.52 81.83 36.73 30.6 27.13 15.59 64.49 18.69 63.03 70.02 38.2 11.65
41.79 41.81 51.9 38.9 30.27 22.55 30.34 44.62 52.18 0.0 51.16 26.43 53.07 8.38 17.8 74.17 23.19 46.22 37.62 52.14 130.59 62.25 73.44 56.6 32.96 67.79 192.6 157.33 114.41 35.84 108.92 130.22 164.5 159.14 131.48 27.86 122.39 53.08 26.01 65.31 45.98 101.36 22.76
255.94 301.55 372.08 268.79 279.48 236.82 56.21 98.59 864.68 0.0 477.6 999.17 384.05 104.46 200.7 404.97 257.77 413.0 422.53 329.96 517.35 442.35 455.84 469.62 357.09 423.74 713.68 1071.52 544.45 205.06 455.55 754.79 689.53 687.52 477.76 132.97 545.2 199.6 52.64 347.35 286.94 259.34 18.66
48.95 24.38 71.91 93.22 78.4 57.66 150.48 232.34 218.89 0.0 377.84 84.78 245.53 31.63 145.32 245.73 252.97 366.58 344.78 176.38 686.21 199.42 286.52 199.2 97.23 402.33 1339.47 3444.93 302.48 100.51 887.66 1082.71 796.19 797.96 871.41 56.69 514.41 390.05 182.72 423.61 484.07 938.74 158.4
9.75 15.96 10.62 19.57 31.47 15.98 351.82 572.46 4.95 0.0 236.32 246.17 237.66 29.07 157.85 446.28 221.5 133.08 264.85 378.82 1378.35 395.03 481.53 396.26 98.83 606.75 2124.2 2053.93 81.24 91.08 1430.61 1559.86 1126.27 1588.5 1342.47 32.3 1869.38 1655.68 479.69 1856.03 935.98 2494.07 365.72
26.83 27.0 36.25 25.12 27.28 20.63 23.34 27.88 43.39 0.0 37.53 25.38 9.79 12.42 13.25 45.46 19.12 32.06 25.05 38.7 60.44 43.93 52.66 47.31 7.76 13.06 114.19 57.72 10.81 23.12 21.03 118.99 113.2 72.87 25.87 26.92 23.57 42.6 13.58 86.8 67.46 59.45 11.37
10.69 9.75 20.88 15.91 12.92 5.92 3.25 10.45 16.85 0.0 30.74 29.08 11.91 7.41 16.88 34.69 25.81 35.47 21.28 33.15 50.27 49.4 51.21 51.34 11.39 14.82 34.24 17.89 9.94 6.48 11.53 49.36 60.03 41.83 15.23 5.52 14.97 10.28 3.04 28.76 55.47 13.46 1.2
5.23 4.23 9.49 6.48 13.83 5.49 70.35 80.94 8.5 0.0 64.35 32.53 27.68 18.1 30.96 57.62 57.94 68.26 56.99 55.37 147.05 67.73 88.87 70.26 12.17 41.77 298.1 263.03 43.89 29.98 228.36 195.93 200.79 235.92 135.75 27.68 305.25 153.25 91.32 164.0 192.02 241.76 103.01
44.48 54.77 59.84 62.51 56.65 56.35 337.88 178.33 48.49 0.0 212.35 47.47 213.8 36.24 87.53 315.32 107.82 155.25 196.46 205.41 749.1 250.86 303.02 231.31 93.15 274.15 1348.09 815.6 581.62 36.62 571.14 854.53 719.04 1171.33 740.28 34.2 850.91 495.56 234.24 264.33 605.64 1189.76 198.25
77.65 75.6 401.89 402.94 225.87 230.01 277.42 266.14 328.84 166.65 448.45 506.01 222.34 168.36 299.19 476.35 238.08 389.63 388.98 383.58 650.38 473.0 536.41 467.12 183.25 256.58 1165.54 1265.16 462.07 84.09 267.95 776.02 1165.79 683.79 385.18 53.54 285.45 663.68 218.57 712.51 684.08 604.92 195.26
27.51 26.26 22.24 15.36 17.7 14.06 47.89 84.83 26.58 0.0 92.99 169.71 119.8 46.77 72.84 116.75 55.38 49.03 58.16 123.95 165.52 117.97 136.85 120.76 111.02 122.57 259.1 263.75 259.04 48.69 144.91 180.36 140.11 310.59 194.68 29.09 202.36 113.26 34.46 127.61 120.84 180.54 22.23
21.2 18.6 59.63 34.55 28.99 15.14 8.67 10.95 67.09 0.0 136.52 45.14 24.81 15.8 27.23 159.17 40.28 136.49 69.66 105.62 180.06 151.47 142.83 135.13 17.71 23.37 187.88 138.94 43.51 24.7 42.98 156.76 440.14 100.91 39.45 28.61 72.04 28.25 7.79 60.57 111.45 31.17 5.32
16.62 9.88 9.98 3.07 12.94 5.27 211.58 314.6 4.01 0.0 46.19 11.86 83.97 4.39 20.19 62.34 43.5 29.82 45.13 51.11 197.07 56.67 79.55 56.25 60.31 95.94 542.24 216.12 233.0 271.88 308.04 449.7 465.47 474.93 297.12 279.38 329.36 259.51 233.32 205.02 266.51 387.22 141.94
24.45 19.89 181.72 147.45 114.9 63.45 41.24 21.63 41.25 0.0 88.6 19.16 27.81 20.27 32.8 94.74 66.16 101.98 68.88 59.61 127.9 75.95 82.23 74.39 17.32 38.57 284.71 148.34 47.46 45.73 94.78 221.28 221.6 120.96 86.69 60.95 106.29 77.65 22.01 74.19 103.36 48.89 20.35
26.65 21.21 80.87 70.17 58.67 29.8 25.01 42.1 57.14 3.11 172.14 130.99 11.58 65.44 119.73 163.65 148.08 169.66 125.57 183.37 216.33 197.56 194.57 188.86 6.01 18.73 204.42 82.59 3.87 24.09 19.79 228.04 218.2 267.2 23.23 30.49 25.64 86.45 26.25 227.23 144.79 106.45 20.5
29.37 32.94 65.82 47.12 46.6 30.75 47.15 59.08 76.78 0.0 130.09 28.56 39.44 60.51 70.64 96.14 80.69 138.53 149.46 71.85 151.67 99.79 104.88 90.19 29.33 46.38 92.44 80.56 38.25 13.69 33.97 90.31 81.72 113.97 42.49 21.66 46.98 115.13 82.61 86.22 113.07 90.95 30.35
3.07 4.63 23.45 19.1 24.19 16.87 17.16 9.45 15.73 0.0 47.82 8.45 20.1 5.59 8.8 56.36 26.32 30.31 50.8 48.56 191.73 52.19 70.66 52.62 6.01 32.96 302.88 220.4 32.94 5.38 82.99 176.13 175.5 394.47 74.38 5.34 133.01 49.03 16.33 32.25 38.99 161.91 13.85
23.84 23.4 26.28 31.58 23.18 22.05 17.21 64.24 74.81 0.0 69.3 29.33 26.46 10.69 20.37 90.13 34.4 81.49 38.69 55.57 123.73 90.89 92.48 69.79 18.72 36.88 189.01 84.29 47.32 12.21 58.45 171.33 202.72 55.5 80.79 9.33 87.58 35.18 13.65 52.54 66.23 56.83 12.59
28.82 29.61 28.64 11.81 13.51 11.77 1.08 4.86 28.31 0.0 40.82 42.17 31.49 6.48 13.79 33.58 15.95 43.14 32.18 28.98 34.58 36.73 39.45 37.21 26.65 36.62 39.4 27.07 21.98 22.8 21.59 35.99 55.37 18.97 24.24 18.0 21.84 9.91 1.15 12.85 14.84 12.21 0.39
17.47 15.18 44.72 45.06 23.27 18.4 19.11 45.63 49.5 0.0 45.1 26.45 14.46 17.56 27.32 52.54 31.14 48.3 34.96 44.77 103.12 56.87 69.79 59.8 11.01 19.56 110.96 88.14 21.68 5.99 16.38 107.22 121.72 69.9 23.23 4.5 19.2 63.83 16.65 90.01 80.94 44.33 13.36
17.52 11.28 44.26 34.18 38.96 36.56 93.75 199.41 21.49 0.0 115.72 40.47 64.63 41.98 75.37 101.18 105.38 142.01 117.8 94.13 241.77 99.75 134.48 110.99 60.11 65.31 374.45 329.23 182.68 95.47 146.5 311.95 444.33 407.52 162.84 120.87 143.0 146.46 90.47 194.01 224.83 371.6 47.69
77.39 68.36 102.87 80.72 53.89 38.48 31.4 42.82 82.3 0.0 162.96 143.79 102.89 96.21 125.28 160.16 150.93 162.92 134.61 152.15 163.61 179.41 179.62 176.48 95.76 114.81 220.23 101.31 99.48 33.16 101.21 171.74 165.8 157.68 114.74 22.82 136.25 49.67 23.84 78.81 55.71 64.68 19.81
186.87 186.25 230.83 244.13 142.93 138.31 17.67 20.64 167.13 0.0 207.04 148.5 163.73 75.23 114.52 194.46 107.34 208.98 178.81 145.48 208.82 194.79 197.74 194.62 156.14 205.44 388.11 211.38 225.04 165.91 177.6 372.98 402.49 278.55 210.75 162.91 190.48 56.26 8.29 106.86 116.0 78.34 3.75
41.56 43.37 35.41 22.68 23.66 17.07 101.43 177.44 66.22 0.0 51.28 21.46 55.03 5.8 16.03 86.87 22.15 42.12 40.31 51.22 155.91 67.15 81.59 62.32 41.86 61.6 201.76 149.74 118.91 127.07 119.76 132.63 141.88 196.96 135.97 106.15 123.99 102.38 70.8 119.35 84.15 172.41 42.95
7.21 6.5 29.12 16.67 26.87 14.03 22.34 16.04 27.85 0.0 40.75 26.1 5.33 18.08 27.21 37.79 35.89 38.56 30.34 41.66 44.58 38.35 40.03 41.06 2.97 6.57 42.14 25.67 5.44 6.47 6.38 44.35 42.17 38.8 8.44 8.02 8.23 52.04 19.01 66.3 48.35 61.7 18.13
295.17 338.63 178.12 129.56 230.2 161.06 241.42 180.43 206.84 0.0 151.49 94.55 202.34 28.4 68.83 212.3 85.02 163.72 117.3 95.32 294.9 174.78 197.09 143.32 134.64 249.36 606.7 187.63 324.04 179.57 391.72 420.56 244.48 467.62 464.15 143.01 508.56 348.17 211.07 242.26 277.86 633.14 367.12
15.09 16.45 13.4 6.96 16.28 8.42 236.74 176.91 25.59 0.0 123.1 25.34 309.32 6.11 21.44 187.18 88.84 84.61 128.61 138.24 619.18 145.2 215.41 144.78 164.15 421.69 1386.69 1589.24 750.21 41.73 992.05 834.57 885.44 1090.9 992.17 34.43 1292.36 328.25 209.93 337.73 392.49 1024.03 133.19
13.94 15.56 19.48 7.79 28.12 15.11 182.51 294.51 45.86 0.0 116.39 33.39 196.5 12.29 31.84 152.24 74.86 88.19 82.62 96.94 403.71 112.92 187.33 92.9 92.68 215.47 896.74 1309.65 627.83 23.96 400.68 560.18 394.84 579.73 633.19 27.8 517.5 194.39 139.78 236.95 182.82 692.4 92.59
88.06 65.18 87.67 79.47 95.59 64.78 128.77 114.25 115.71 0.0 118.73 114.74 60.43 48.49 94.82 150.38 65.1 84.11 69.19 125.33 196.52 179.13 189.57 172.28 49.07 60.61 221.38 122.08 93.54 39.91 82.31 235.93 160.72 181.15 115.5 31.42 139.47 194.09 121.36 216.72 154.05 190.14 160.63
13.44 12.82 34.06 20.88 23.51 16.41 12.16 12.66 36.56 0.0 60.92 75.75 15.55 32.51 49.92 52.43 42.34 58.77 47.12 58.2 49.28 54.52 54.84 55.15 13.85 19.89 44.41 61.71 9.02 22.07 17.12 41.68 53.26 62.27 16.86 33.7 16.06 25.93 9.2 48.25 30.91 28.1 7.23
31.31 24.14 13.94 6.48 9.73 5.61 59.91 173.22 52.4 0.0 57.68 27.0 90.84 13.03 27.37 49.4 54.45 48.31 63.35 41.96 179.41 53.02 67.54 47.35 98.85 95.53 212.46 321.94 300.26 177.54 191.84 148.59 164.69 359.16 207.89 168.01 205.87 95.1 67.93 105.96 87.39 335.02 40.78
PBANKA_1139500 (CCR4-2)
 39.04 38.04 85.67 74.68 43.98 34.16 5.41 10.15 54.27 0.0 50.38 25.96 19.49 7.63 22.23 51.84 35.44 59.77 38.38 41.42 86.54 55.61 61.13 53.71 17.72 24.25 95.94 43.68 32.89 32.52 38.56 120.76 94.49 35.55 34.84 34.24 40.57 20.69 4.79 35.01 28.94 21.04 2.8
27.21 28.57 29.92 25.88 44.28 25.16 26.17 72.86 53.25 0.0 28.2 17.09 44.35 8.18 21.04 31.8 15.06 34.43 19.76 22.15 42.75 28.62 30.78 27.38 22.9 54.22 95.84 88.39 129.29 13.3 113.09 77.88 12.07 9.92 106.81 5.24 100.2 29.57 38.44 28.72 19.31 37.93 17.32
45.99 26.69 230.12 148.66 169.98 109.58 42.63 97.15 96.49 0.0 378.34 258.44 27.28 226.4 316.53 413.52 303.69 352.66 337.89 392.68 455.89 479.31 454.95 462.93 35.88 32.64 386.76 215.48 18.51 42.43 47.95 396.17 386.18 512.93 39.9 71.2 74.58 284.48 45.48 359.1 591.74 369.39 23.79
126.67 126.1 161.6 153.68 92.7 69.93 29.51 39.76 168.31 0.0 111.54 112.25 86.79 16.74 37.96 152.38 41.72 84.63 71.09 124.28 172.39 155.9 178.63 169.17 81.43 94.37 167.03 171.59 88.7 78.64 85.89 213.54 259.14 118.46 80.39 82.34 84.18 77.06 43.1 103.47 132.11 59.99 15.8
43.41 45.55 68.73 48.56 42.79 32.59 72.18 180.55 116.81 0.0 171.17 85.76 59.09 55.82 102.77 137.94 64.82 161.26 122.71 99.89 113.37 120.12 109.95 109.14 50.62 78.7 63.5 46.9 25.67 39.82 27.65 69.62 62.01 54.52 33.22 47.8 20.24 151.19 55.97 127.01 94.63 162.97 28.81
4.31 3.98 74.12 38.55 48.17 20.67 17.07 17.22 51.44 0.0 112.37 61.89 1.23 41.49 69.33 153.3 94.81 79.5 66.01 119.7 151.43 124.3 110.79 112.7 1.34 2.43 104.17 63.65 2.05 12.14 7.53 116.36 129.65 153.09 3.86 24.54 2.94 71.99 19.54 134.66 83.98 141.96 10.97
22.97 14.48 76.13 62.59 54.38 28.28 41.43 55.06 26.99 0.0 93.57 53.72 7.74 32.72 55.85 91.82 59.95 102.83 82.56 86.03 109.06 92.76 93.51 88.93 8.86 10.44 109.64 39.38 5.87 17.56 15.87 106.34 114.75 106.4 13.72 29.2 15.9 92.69 27.72 125.91 98.27 112.68 25.63
34.15 34.6 61.47 35.8 35.62 30.41 28.03 39.98 52.49 0.0 54.23 28.22 34.84 7.9 17.79 61.35 28.0 45.25 27.63 33.28 105.09 53.91 66.84 55.02 18.64 45.13 160.28 168.49 62.38 22.1 64.71 124.72 73.68 44.7 76.12 19.09 80.69 53.3 23.74 71.65 46.48 49.86 15.22
16.9 12.8 21.54 14.43 11.61 5.84 4.41 9.06 10.4 0.0 100.38 92.6 50.18 30.33 53.16 93.14 54.2 118.54 68.15 79.2 109.35 121.5 116.82 113.02 57.72 53.26 89.01 69.03 73.42 40.42 67.44 80.68 263.89 68.24 63.51 45.81 71.63 18.65 3.8 49.61 75.05 33.99 2.4
145.51 140.22 148.94 127.44 87.05 97.63 138.74 264.17 153.1 0.0 149.7 56.08 140.73 20.64 39.72 200.3 78.62 138.87 112.42 117.01 265.14 149.23 185.49 157.76 94.34 161.72 457.44 270.22 260.33 217.22 291.33 442.99 386.08 368.36 277.62 276.17 281.0 186.46 106.51 267.4 188.13 214.89 55.59
4.38 9.47 16.4 3.09 25.53 7.09 404.98 685.15 7.15 0.0 323.64 49.74 356.04 5.88 35.37 289.01 238.98 163.88 231.59 298.76 1024.46 233.52 361.63 221.17 146.49 530.97 2217.29 3263.72 834.87 33.37 1113.66 1339.75 957.62 1323.01 1288.77 30.45 1601.03 543.57 334.19 259.28 353.48 1102.62 290.0
PBANKA_1403700 (ApiAP2)
 54.42 49.46 54.02 42.31 48.51 52.78 14.06 21.4 96.79 0.0 71.79 33.64 60.98 10.22 19.5 64.36 29.77 71.57 42.82 38.76 90.5 60.21 64.78 52.88 33.3 65.23 168.55 207.85 182.02 25.41 113.03 125.06 91.26 41.9 128.63 14.43 150.28 27.17 15.99 38.16 26.9 29.59 8.76
113.07 98.35 203.48 186.93 125.0 97.4 98.53 165.68 145.1 0.0 54.26 13.42 48.1 20.61 33.18 52.27 41.83 56.66 58.45 41.07 82.38 44.08 51.18 55.24 46.12 57.52 175.85 71.63 88.39 64.95 73.51 186.38 231.79 99.85 83.86 71.04 91.43 120.63 82.95 182.61 137.86 75.84 35.04
5.13 5.85 19.93 13.54 16.63 11.38 14.14 26.76 24.42 0.0 53.51 34.77 6.33 28.36 30.03 54.41 49.32 46.56 33.04 54.31 60.79 45.24 47.92 57.58 4.04 7.49 59.66 37.98 8.87 2.36 6.63 59.38 43.57 46.98 10.62 4.29 11.85 47.63 16.78 81.98 47.45 52.12 10.93
4.24 4.73 6.58 1.94 9.99 2.58 51.77 87.44 5.1 0.0 44.64 16.85 84.35 3.72 9.47 62.88 29.52 40.65 40.86 42.18 188.41 57.0 66.34 45.66 52.02 114.67 410.76 422.75 258.04 21.64 320.89 271.98 415.73 448.54 332.92 16.22 458.41 71.06 54.3 61.62 110.87 441.26 32.55
4.71 15.74 31.09 6.61 44.71 18.68 147.12 117.74 30.66 0.0 901.68 126.59 275.06 93.9 190.36 483.42 567.66 654.35 761.11 612.89 2418.05 506.09 809.84 634.43 117.13 376.24 3897.69 6027.25 813.73 61.64 863.34 833.54 2555.05 2865.39 811.22 54.89 1208.56 694.18 52.31 376.16 580.1 1611.27 49.06

Details

Raw expression values (TPM normalized), Green cells indicate low expression and red high. (Dark gray cells indicate missing values)