PF3D7_0106300 (ATP6)

Aliases : ATP6

Description : SSF81660: "P-type ATPase, cytoplasmic domain N", SSF81665: "P-type ATPase, transmembrane domain superfamily", SSF81653: "P-type ATPase, A domain superfamily", SSF56784: HAD-like superfamily. Pfam domain(s): PF00689: "Cation transporting ATPase, C-terminus", PF00690: "Cation transporter/ATPase, N-terminus", PF00122: E1-E2 ATPase, PF13246: Cation transport ATPase (P-type).

Gene families : OG_01_0000510 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000510_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0106300
Cluster	P. falciparum: Cluster_17

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0207000	SERCA	SSF56784: HAD-like superfamily, SSF81653: P-type ATPase,...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005388	calcium-transporting ATPase activity	TAS	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	None	Extended
BP	GO:0006812	cation transport	None	Extended
BP	GO:0006816	calcium ion transport	TAS	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008324	cation transmembrane transporter activity	None	Extended
MF	GO:0015075	ion transmembrane transporter activity	None	Extended
MF	GO:0015085	calcium ion transmembrane transporter activity	None	Extended
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
MF	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	None	Extended
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019829	cation-transporting ATPase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022853	active ion transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0022890	inorganic cation transmembrane transporter activity	None	Extended
BP	GO:0030001	metal ion transport	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IDA	PlasmoDB
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042625	ATPase coupled ion transmembrane transporter activity	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
MF	GO:0046873	metal ion transmembrane transporter activity	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0070838	divalent metal ion transport	None	Extended
BP	GO:0072511	divalent inorganic cation transport	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	Predicted GO
CC	GO:0000502	proteasome complex	IEP	Predicted GO
BP	GO:0002376	immune system process	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Predicted GO
MF	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0004825	methionine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004839	ubiquitin activating enzyme activity	IEP	Predicted GO
MF	GO:0005092	GDP-dissociation inhibitor activity	IEP	Predicted GO
MF	GO:0005093	Rab GDP-dissociation inhibitor activity	IEP	Predicted GO
MF	GO:0005096	GTPase activator activity	IEP	Predicted GO
CC	GO:0005581	collagen trimer	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005798	Golgi-associated vesicle	IEP	Predicted GO
CC	GO:0005802	trans-Golgi network	IEP	Predicted GO
CC	GO:0005838	proteasome regulatory particle	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006103	2-oxoglutarate metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006431	methionyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0006891	intra-Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0007029	endoplasmic reticulum organization	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009894	regulation of catabolic process	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
MF	GO:0016208	AMP binding	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030126	COPI vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	IEP	Predicted GO
CC	GO:0030135	coated vesicle	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0030695	GTPase regulator activity	IEP	Predicted GO
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0031984	organelle subcompartment	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
BP	GO:0042176	regulation of protein catabolic process	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044053	translocation of peptides or proteins into host cell cytoplasm	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044431	Golgi apparatus part	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
BP	GO:0050789	regulation of biological process	IEP	Predicted GO
BP	GO:0051246	regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
CC	GO:0070971	endoplasmic reticulum exit site	IEP	Predicted GO
BP	GO:0071344	diphosphate metabolic process	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
CC	GO:0071782	endoplasmic reticulum tubular network	IEP	Predicted GO
BP	GO:0071786	endoplasmic reticulum tubular network organization	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
CC	GO:0098791	Golgi subcompartment	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
CC	GO:0098827	endoplasmic reticulum subcompartment	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004014	ATPase_P-typ_cation-transptr_N	9	76
IPR006068	ATPase_P-typ_cation-transptr_C	998	1210

External Links

PlasmoDB	MAL1P1.54
PlasmoDB	PFA0310c

PF3D7_0106300 (ATP6)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation