PF3D7_0108000

Description : SSF56235: "Nucleophile aminohydrolases, N-terminal". Pfam domain(s): PF00227: Proteasome subunit.

Gene families : OG_01_0000507 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000507_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0108000
Cluster	P. falciparum: Cluster_31

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0205400	No alias	SSF56235: Nucleophile aminohydrolases, N-terminal. Pfam...	0.07	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004175	endopeptidase activity	ISS	PlasmoDB
MF	GO:0004298	threonine-type endopeptidase activity	IEA	Interproscan predictions
MF	GO:0004298	threonine-type endopeptidase activity	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005839	proteasome core complex	IEA	Interproscan predictions
CC	GO:0005839	proteasome core complex	IEA	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0019774	proteasome core complex, beta-subunit complex	ISS	PlasmoDB
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEA	Interproscan predictions
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEA	PlasmoDB
MF	GO:0070003	threonine-type peptidase activity	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000234	phosphoethanolamine N-methyltransferase activity	IEP	Predicted GO
BP	GO:0001678	cellular glucose homeostasis	IEP	Predicted GO
BP	GO:0003006	developmental process involved in reproduction	IEP	Predicted GO
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0004013	adenosylhomocysteinase activity	IEP	Predicted GO
MF	GO:0004326	tetrahydrofolylpolyglutamate synthase activity	IEP	Predicted GO
MF	GO:0004372	glycine hydroxymethyltransferase activity	IEP	Predicted GO
MF	GO:0004396	hexokinase activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004775	succinate-CoA ligase (ADP-forming) activity	IEP	Predicted GO
MF	GO:0004791	thioredoxin-disulfide reductase activity	IEP	Predicted GO
MF	GO:0004825	methionine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005375	copper ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005483	soluble NSF attachment protein activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005536	glucose binding	IEP	Predicted GO
CC	GO:0005672	transcription factor TFIIA complex	IEP	Predicted GO
CC	GO:0005740	mitochondrial envelope	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005784	Sec61 translocon complex	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005868	cytoplasmic dynein complex	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006090	pyruvate metabolic process	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006096	glycolytic process	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006337	nucleosome disassembly	IEP	Predicted GO
BP	GO:0006431	methionyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006545	glycine biosynthetic process	IEP	Predicted GO
BP	GO:0006563	L-serine metabolic process	IEP	Predicted GO
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Predicted GO
BP	GO:0006627	protein processing involved in protein targeting to mitochondrion	IEP	Predicted GO
BP	GO:0006662	glycerol ether metabolic process	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006733	oxidoreduction coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006757	ATP generation from ADP	IEP	Predicted GO
BP	GO:0006760	folic acid-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0007530	sex determination	IEP	Predicted GO
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	IEP	Predicted GO
CC	GO:0008250	oligosaccharyltransferase complex	IEP	Predicted GO
BP	GO:0008535	respiratory chain complex IV assembly	IEP	Predicted GO
MF	GO:0008841	dihydrofolate synthase activity	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009070	serine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009108	coenzyme biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009166	nucleotide catabolic process	IEP	Predicted GO
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015037	peptide disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015038	glutathione disulfide oxidoreductase activity	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
BP	GO:0016052	carbohydrate catabolic process	IEP	Predicted GO
BP	GO:0016053	organic acid biosynthetic process	IEP	Predicted GO
CC	GO:0016272	prefoldin complex	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	IEP	Predicted GO
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Predicted GO
MF	GO:0016801	hydrolase activity, acting on ether bonds	IEP	Predicted GO
MF	GO:0016802	trialkylsulfonium hydrolase activity	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
CC	GO:0017087	mitochondrial processing peptidase complex	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0018904	ether metabolic process	IEP	Predicted GO
CC	GO:0019005	SCF ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
BP	GO:0019264	glycine biosynthetic process from serine	IEP	Predicted GO
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
CC	GO:0030904	retromer complex	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
BP	GO:0032392	DNA geometric change	IEP	Predicted GO
BP	GO:0032446	protein modification by small protein conjugation	IEP	Predicted GO
BP	GO:0032508	DNA duplex unwinding	IEP	Predicted GO
BP	GO:0032879	regulation of localization	IEP	Predicted GO
BP	GO:0032986	protein-DNA complex disassembly	IEP	Predicted GO
BP	GO:0033500	carbohydrate homeostasis	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034982	mitochondrial protein processing	IEP	Predicted GO
CC	GO:0035145	exon-exon junction complex	IEP	Predicted GO
BP	GO:0035434	copper ion transmembrane transport	IEP	Predicted GO
BP	GO:0035999	tetrahydrofolate interconversion	IEP	Predicted GO
BP	GO:0042136	neurotransmitter biosynthetic process	IEP	Predicted GO
MF	GO:0042393	histone binding	IEP	Predicted GO
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0042593	glucose homeostasis	IEP	Predicted GO
BP	GO:0042866	pyruvate biosynthetic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0043248	proteasome assembly	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
BP	GO:0045116	protein neddylation	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046031	ADP metabolic process	IEP	Predicted GO
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Predicted GO
BP	GO:0046416	D-amino acid metabolic process	IEP	Predicted GO
BP	GO:0046434	organophosphate catabolic process	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
BP	GO:0046653	tetrahydrofolate metabolic process	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0046939	nucleotide phosphorylation	IEP	Predicted GO
MF	GO:0048029	monosaccharide binding	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0048306	calcium-dependent protein binding	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0050794	regulation of cellular process	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
BP	GO:0051049	regulation of transport	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051188	cofactor biosynthetic process	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
BP	GO:0055065	metal ion homeostasis	IEP	Predicted GO
BP	GO:0055074	calcium ion homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0060627	regulation of vesicle-mediated transport	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
BP	GO:0070178	D-serine metabolic process	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
CC	GO:0071256	translocon complex	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
BP	GO:0072507	divalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
BP	GO:1901292	nucleoside phosphate catabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001353	Proteasome_sua/b	8	202

External Links

PlasmoDB	MAL1P2.08
PlasmoDB	PFA0400c

PF3D7_0108000

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation