PF3D7_0111800

Description : SSF55418: Translation Initiation factor eIF- 4e-like. Pfam domain(s): PF01652: Eukaryotic initiation factor 4E.

Gene families : OG_01_0002301 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002301_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0111800
Cluster	P. falciparum: Cluster_28

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0202000	No alias	SSF55418: Translation Initiation factor eIF- 4e-like....	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	Interproscan predictions
MF	GO:0003723	RNA binding	IEA	PlasmoDB
MF	GO:0003743	translation initiation factor activity	IEA	Interproscan predictions
MF	GO:0003743	translation initiation factor activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	Interproscan predictions
CC	GO:0005737	cytoplasm	IEA	PlasmoDB
BP	GO:0006412	translation	IEA	PlasmoDB
BP	GO:0006413	translational initiation	IEA	Interproscan predictions
BP	GO:0006413	translational initiation	IEA	PlasmoDB
BP	GO:0006417	regulation of translation	IEA	PlasmoDB
BP	GO:0006518	peptide metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010608	posttranscriptional regulation of gene expression	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0032268	regulation of cellular protein metabolic process	None	Extended
BP	GO:0034248	regulation of cellular amide metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043043	peptide biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0043604	amide biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000154	rRNA modification	IEP	Predicted GO
MF	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	IEP	Predicted GO
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Predicted GO
MF	GO:0003682	chromatin binding	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0004823	leucine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005087	Ran guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005201	extracellular matrix structural constituent	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005527	macrolide binding	IEP	Predicted GO
MF	GO:0005528	FK506 binding	IEP	Predicted GO
CC	GO:0005581	collagen trimer	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005759	mitochondrial matrix	IEP	Predicted GO
BP	GO:0006429	leucyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0007059	chromosome segregation	IEP	Predicted GO
MF	GO:0008536	Ran GTPase binding	IEP	Predicted GO
MF	GO:0008649	rRNA methyltransferase activity	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0010033	response to organic substance	IEP	Predicted GO
MF	GO:0016433	rRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0017016	Ras GTPase binding	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
BP	GO:0030150	protein import into mitochondrial matrix	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
MF	GO:0030544	Hsp70 protein binding	IEP	Predicted GO
MF	GO:0042802	identical protein binding	IEP	Predicted GO
MF	GO:0042803	protein homodimerization activity	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0044743	protein transmembrane import into intracellular organelle	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
MF	GO:0051879	Hsp90 protein binding	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Predicted GO
BP	GO:1990542	mitochondrial transmembrane transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001040	TIF_eIF_4E	255	408

External Links

PlasmoDB	MAL1P2.43
PlasmoDB	PFA0570w

PF3D7_0111800

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation