PF3D7_0203300 (ERCC1)

Aliases : ERCC1

Description : SSF47781: RuvA domain 2-like, SSF52980: Restriction endonuclease type II-like. Pfam domain(s): PF03834: Binding domain of DNA repair protein Ercc1 (rad10/Swi10).

Gene families : OG_01_0000541 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000541_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0203300
Cluster	P. falciparum: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0301200	ERCC1	SSF47781: RuvA domain 2-like, SSF52980: Restriction...	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	ISS	PlasmoDB
MF	GO:0003684	damaged DNA binding	IEA	Interproscan predictions
MF	GO:0003684	damaged DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	IEA	Interproscan predictions
MF	GO:0004519	endonuclease activity	IEA	PlasmoDB
MF	GO:0004520	endodeoxyribonuclease activity	ISS	PlasmoDB
MF	GO:0004536	deoxyribonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan predictions
CC	GO:0005634	nucleus	IEA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IEA	Interproscan predictions
BP	GO:0006281	DNA repair	IEA	PlasmoDB
BP	GO:0006289	nucleotide-excision repair	ISS	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IEP	Predicted GO
BP	GO:0000338	protein deneddylation	IEP	Predicted GO
MF	GO:0001047	core promoter binding	IEP	Predicted GO
MF	GO:0001067	regulatory region nucleic acid binding	IEP	Predicted GO
BP	GO:0001505	regulation of neurotransmitter levels	IEP	Predicted GO
MF	GO:0004047	aminomethyltransferase activity	IEP	Predicted GO
MF	GO:0004112	cyclic-nucleotide phosphodiesterase activity	IEP	Predicted GO
MF	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	IEP	Predicted GO
MF	GO:0004484	mRNA guanylyltransferase activity	IEP	Predicted GO
MF	GO:0004730	pseudouridylate synthase activity	IEP	Predicted GO
MF	GO:0004738	pyruvate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity	IEP	Predicted GO
MF	GO:0004750	ribulose-phosphate 3-epimerase activity	IEP	Predicted GO
MF	GO:0004788	thiamine diphosphokinase activity	IEP	Predicted GO
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Predicted GO
CC	GO:0005751	mitochondrial respiratory chain complex IV	IEP	Predicted GO
CC	GO:0005882	intermediate filament	IEP	Predicted GO
BP	GO:0006085	acetyl-CoA biosynthetic process	IEP	Predicted GO
BP	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	IEP	Predicted GO
BP	GO:0006370	7-methylguanosine mRNA capping	IEP	Predicted GO
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006544	glycine metabolic process	IEP	Predicted GO
BP	GO:0006546	glycine catabolic process	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006772	thiamine metabolic process	IEP	Predicted GO
BP	GO:0006790	sulfur compound metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	IEP	Predicted GO
MF	GO:0008192	RNA guanylyltransferase activity	IEP	Predicted GO
BP	GO:0009063	cellular amino acid catabolic process	IEP	Predicted GO
BP	GO:0009071	serine family amino acid catabolic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009229	thiamine diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009452	7-methylguanosine RNA capping	IEP	Predicted GO
CC	GO:0010494	cytoplasmic stress granule	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
BP	GO:0016073	snRNA metabolic process	IEP	Predicted GO
BP	GO:0016180	snRNA processing	IEP	Predicted GO
MF	GO:0016778	diphosphotransferase activity	IEP	Predicted GO
MF	GO:0016854	racemase and epimerase activity	IEP	Predicted GO
MF	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0017148	negative regulation of translation	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
MF	GO:0019843	rRNA binding	IEP	Predicted GO
MF	GO:0030551	cyclic nucleotide binding	IEP	Predicted GO
MF	GO:0030552	cAMP binding	IEP	Predicted GO
MF	GO:0030975	thiamine binding	IEP	Predicted GO
BP	GO:0034249	negative regulation of cellular amide metabolic process	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034472	snRNA 3'-end processing	IEP	Predicted GO
BP	GO:0034477	U6 snRNA 3'-end processing	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0035384	thioester biosynthetic process	IEP	Predicted GO
BP	GO:0036260	RNA capping	IEP	Predicted GO
BP	GO:0042133	neurotransmitter metabolic process	IEP	Predicted GO
BP	GO:0042135	neurotransmitter catabolic process	IEP	Predicted GO
BP	GO:0042357	thiamine diphosphate metabolic process	IEP	Predicted GO
BP	GO:0042723	thiamine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0043549	regulation of kinase activity	IEP	Predicted GO
BP	GO:0043628	ncRNA 3'-end processing	IEP	Predicted GO
MF	GO:0044212	transcription regulatory region DNA binding	IEP	Predicted GO
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
CC	GO:0045254	pyruvate dehydrogenase complex	IEP	Predicted GO
CC	GO:0045277	respiratory chain complex IV	IEP	Predicted GO
BP	GO:0045859	regulation of protein kinase activity	IEP	Predicted GO
BP	GO:0051338	regulation of transferase activity	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
MF	GO:0070568	guanylyltransferase activity	IEP	Predicted GO
BP	GO:0071616	acyl-CoA biosynthetic process	IEP	Predicted GO
BP	GO:0071900	regulation of protein serine/threonine kinase activity	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Predicted GO
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004579	ERCC1/RAD10/SWI10	48	159

External Links

PlasmoDB	812627
PlasmoDB	PF02_0031
PlasmoDB	PFB0160w

PF3D7_0203300 (ERCC1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation