PF3D7_0205500

Description : SSF47819: HRDC-like superfamily. Pfam domain(s): PF03874: RNA polymerase Rpb4.

Gene families : OG_01_0000549 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000549_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0205500
Cluster	P. falciparum: Cluster_35

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0303200	No alias	SSF47819: HRDC-like superfamily. Pfam domain(s):...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	PlasmoDB
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	ISS	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006351	transcription, DNA-templated	None	Extended
BP	GO:0006352	DNA-templated transcription, initiation	IEA	Interproscan predictions
BP	GO:0006352	DNA-templated transcription, initiation	IEA	PlasmoDB
BP	GO:0006366	transcription by RNA polymerase II	ISS	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
CC	GO:0030880	RNA polymerase complex	IEA	Interproscan predictions
CC	GO:0030880	RNA polymerase complex	IEA	PlasmoDB
BP	GO:0032774	RNA biosynthetic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0034062	5'-3' RNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	IEA	PlasmoDB
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:0097659	nucleic acid-templated transcription	None	Extended
MF	GO:0097747	RNA polymerase activity	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000123	histone acetyltransferase complex	IEP	Predicted GO
CC	GO:0000178	exosome (RNase complex)	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000380	alternative mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
CC	GO:0000408	EKC/KEOPS complex	IEP	Predicted GO
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
BP	GO:0001678	cellular glucose homeostasis	IEP	Predicted GO
BP	GO:0002143	tRNA wobble position uridine thiolation	IEP	Predicted GO
CC	GO:0002189	ribose phosphate diphosphokinase complex	IEP	Predicted GO
BP	GO:0003006	developmental process involved in reproduction	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IEP	Predicted GO
MF	GO:0004396	hexokinase activity	IEP	Predicted GO
MF	GO:0004523	RNA-DNA hybrid ribonuclease activity	IEP	Predicted GO
MF	GO:0004540	ribonuclease activity	IEP	Predicted GO
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0005102	signaling receptor binding	IEP	Predicted GO
MF	GO:0005125	cytokine activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005253	anion channel activity	IEP	Predicted GO
MF	GO:0005254	chloride channel activity	IEP	Predicted GO
MF	GO:0005536	glucose binding	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005732	small nucleolar ribonucleoprotein complex	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005956	protein kinase CK2 complex	IEP	Predicted GO
BP	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0006090	pyruvate metabolic process	IEP	Predicted GO
BP	GO:0006096	glycolytic process	IEP	Predicted GO
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	IEP	Predicted GO
BP	GO:0006757	ATP generation from ADP	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006879	cellular iron ion homeostasis	IEP	Predicted GO
BP	GO:0007530	sex determination	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
MF	GO:0008452	RNA ligase activity	IEP	Predicted GO
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009166	nucleotide catabolic process	IEP	Predicted GO
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0015074	DNA integration	IEP	Predicted GO
MF	GO:0015108	chloride transmembrane transporter activity	IEP	Predicted GO
CC	GO:0015935	small ribosomal subunit	IEP	Predicted GO
MF	GO:0016018	cyclosporin A binding	IEP	Predicted GO
BP	GO:0016052	carbohydrate catabolic process	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
BP	GO:0016226	iron-sulfur cluster assembly	IEP	Predicted GO
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
MF	GO:0019153	protein-disulfide reductase (glutathione) activity	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
CC	GO:0022627	cytosolic small ribosomal subunit	IEP	Predicted GO
CC	GO:0030532	small nuclear ribonucleoprotein complex	IEP	Predicted GO
MF	GO:0030545	receptor regulator activity	IEP	Predicted GO
BP	GO:0031163	metallo-sulfur cluster assembly	IEP	Predicted GO
CC	GO:0031248	protein acetyltransferase complex	IEP	Predicted GO
MF	GO:0031404	chloride ion binding	IEP	Predicted GO
BP	GO:0032196	transposition	IEP	Predicted GO
BP	GO:0032447	protein urmylation	IEP	Predicted GO
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0033500	carbohydrate homeostasis	IEP	Predicted GO
BP	GO:0034227	tRNA thio-modification	IEP	Predicted GO
CC	GO:0035145	exon-exon junction complex	IEP	Predicted GO
MF	GO:0042277	peptide binding	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0042593	glucose homeostasis	IEP	Predicted GO
BP	GO:0042866	pyruvate biosynthetic process	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
MF	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044451	nucleoplasm part	IEP	Predicted GO
BP	GO:0046031	ADP metabolic process	IEP	Predicted GO
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046391	5-phosphoribose 1-diphosphate metabolic process	IEP	Predicted GO
BP	GO:0046434	organophosphate catabolic process	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
CC	GO:0046540	U4/U6 x U5 tri-snRNP complex	IEP	Predicted GO
BP	GO:0046916	cellular transition metal ion homeostasis	IEP	Predicted GO
BP	GO:0046939	nucleotide phosphorylation	IEP	Predicted GO
MF	GO:0048018	receptor ligand activity	IEP	Predicted GO
MF	GO:0048029	monosaccharide binding	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
MF	GO:0051536	iron-sulfur cluster binding	IEP	Predicted GO
MF	GO:0051540	metal cluster binding	IEP	Predicted GO
BP	GO:0055072	iron ion homeostasis	IEP	Predicted GO
BP	GO:0055076	transition metal ion homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
CC	GO:0097525	spliceosomal snRNP complex	IEP	Predicted GO
CC	GO:0097526	spliceosomal tri-snRNP complex	IEP	Predicted GO
CC	GO:0120114	Sm-like protein family complex	IEP	Predicted GO
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Predicted GO
BP	GO:1901292	nucleoside phosphate catabolic process	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:1902493	acetyltransferase complex	IEP	Predicted GO
CC	GO:1905354	exoribonuclease complex	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR005574	RPB4/RPC9	39	125

External Links

PlasmoDB	812647
PlasmoDB	PF02_0051
PlasmoDB	PFB0245c

PF3D7_0205500

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation