PF3D7_0207600 (SERA5)

Aliases : SERA5

Description : SSF54001: Papain-like cysteine peptidase superfamily. Pfam domain(s): PF00112: Papain family cysteine protease.

Gene families : OG_01_0000019 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000019_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0207600
Cluster	P. falciparum: Cluster_37

Target	Alias	Description	ECC score	Gene Family Method
PBANKA_0304800	SERA4	SSF54001: Papain-like cysteine peptidase superfamily....	0.04	Orthofinderv1.1.8
PBANKA_0305000	SERA2	SSF54001: Papain-like cysteine peptidase superfamily....	0.04	Orthofinderv1.1.8
PBANKA_0305100	SERA1	SSF54001: Papain-like cysteine peptidase superfamily....	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
BP	GO:0002376	immune system process	None	Extended
BP	GO:0002377	immunoglobulin production	IDA	PlasmoDB
BP	GO:0002440	production of molecular mediator of immune response	None	Extended
BP	GO:0002682	regulation of immune system process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006508	proteolysis	IDA	PlasmoDB
BP	GO:0006508	proteolysis	IEA	Interproscan predictions
BP	GO:0006508	proteolysis	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	IDA	PlasmoDB
MF	GO:0008234	cysteine-type peptidase activity	IEA	Interproscan predictions
MF	GO:0008234	cysteine-type peptidase activity	IEA	PlasmoDB
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0020003	symbiont-containing vacuole	IDA	PlasmoDB
CC	GO:0031982	vesicle	None	Extended
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033655	host cell cytoplasm part	None	Extended
BP	GO:0035890	exit from host	None	Extended
BP	GO:0035891	exit from host cell	IMP	PlasmoDB
BP	GO:0040011	locomotion	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043230	extracellular organelle	None	Extended
CC	GO:0044217	other organism part	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044421	extracellular region part	None	Extended
BP	GO:0048583	regulation of response to stimulus	None	Extended
BP	GO:0050776	regulation of immune response	TAS	PlasmoDB
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0051701	interaction with host	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0052126	movement in host environment	None	Extended
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	None	Extended
BP	GO:0065007	biological regulation	None	Extended
CC	GO:0065010	extracellular membrane-bounded organelle	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
CC	GO:1903561	extracellular vesicle	RCA	PlasmoDB

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Predicted GO
CC	GO:0000502	proteasome complex	IEP	Predicted GO
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0004103	choline kinase activity	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005326	neurotransmitter transporter activity	IEP	Predicted GO
MF	GO:0005328	neurotransmitter:sodium symporter activity	IEP	Predicted GO
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005971	ribonucleoside-diphosphate reductase complex	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006471	protein ADP-ribosylation	IEP	Predicted GO
BP	GO:0006656	phosphatidylcholine biosynthetic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006836	neurotransmitter transport	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0007029	endoplasmic reticulum organization	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008521	acetyl-CoA transmembrane transporter activity	IEP	Predicted GO
BP	GO:0009060	aerobic respiration	IEP	Predicted GO
CC	GO:0009376	HslUV protease complex	IEP	Predicted GO
BP	GO:0009894	regulation of catabolic process	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015095	magnesium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015370	solute:sodium symporter activity	IEP	Predicted GO
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015693	magnesium ion transport	IEP	Predicted GO
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016757	transferase activity, transferring glycosyl groups	IEP	Predicted GO
MF	GO:0016758	transferase activity, transferring hexosyl groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	IEP	Predicted GO
BP	GO:0018103	protein C-linked glycosylation	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0030036	actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0030837	negative regulation of actin filament polymerization	IEP	Predicted GO
BP	GO:0031333	negative regulation of protein complex assembly	IEP	Predicted GO
CC	GO:0031597	cytosolic proteasome complex	IEP	Predicted GO
BP	GO:0032272	negative regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032507	maintenance of protein location in cell	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0033265	choline binding	IEP	Predicted GO
CC	GO:0034399	nuclear periphery	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0042165	neurotransmitter binding	IEP	Predicted GO
BP	GO:0042176	regulation of protein catabolic process	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
BP	GO:0042989	sequestering of actin monomers	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
CC	GO:0043264	extracellular non-membrane-bounded organelle	IEP	Predicted GO
MF	GO:0043495	protein membrane anchor	IEP	Predicted GO
MF	GO:0043565	sequence-specific DNA binding	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044454	nuclear chromosome part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0045185	maintenance of protein location	IEP	Predicted GO
BP	GO:0045333	cellular respiration	IEP	Predicted GO
BP	GO:0046470	phosphatidylcholine metabolic process	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0051184	cofactor transmembrane transporter activity	IEP	Predicted GO
MF	GO:0051185	coenzyme transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051262	protein tetramerization	IEP	Predicted GO
BP	GO:0051494	negative regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0051651	maintenance of location in cell	IEP	Predicted GO
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Predicted GO
MF	GO:0070064	proline-rich region binding	IEP	Predicted GO
MF	GO:0070405	ammonium ion binding	IEP	Predicted GO
MF	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0071344	diphosphate metabolic process	IEP	Predicted GO
CC	GO:0085026	tubovesicular membrane network	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
MF	GO:1901682	sulfur compound transmembrane transporter activity	IEP	Predicted GO
BP	GO:1902904	negative regulation of supramolecular fiber organization	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000668	Peptidase_C1A_C	585	810

External Links

PlasmoDB	812668
PlasmoDB	PF02_0072
PlasmoDB	PFB0340c

PF3D7_0207600 (SERA5)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation