PF3D7_0208000 (SERA1)

Aliases : SERA1

Description : SSF54001: Papain-like cysteine peptidase superfamily. Pfam domain(s): PF00112: Papain family cysteine protease.

Gene families : OG_01_0000019 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000019_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0208000
Cluster	P. falciparum: Cluster_17

Target	Alias	Description	ECC score	Gene Family Method
PBANKA_0304800	SERA4	SSF54001: Papain-like cysteine peptidase superfamily....	0.03	Orthofinderv1.1.8
PBANKA_0305000	SERA2	SSF54001: Papain-like cysteine peptidase superfamily....	0.05	Orthofinderv1.1.8
PBANKA_0305100	SERA1	SSF54001: Papain-like cysteine peptidase superfamily....	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
BP	GO:0002376	immune system process	None	Extended
BP	GO:0002377	immunoglobulin production	IDA	PlasmoDB
BP	GO:0002440	production of molecular mediator of immune response	None	Extended
BP	GO:0002682	regulation of immune system process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006508	proteolysis	ISS	PlasmoDB
BP	GO:0006508	proteolysis	IEA	Interproscan predictions
BP	GO:0006508	proteolysis	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	ISS	PlasmoDB
MF	GO:0008234	cysteine-type peptidase activity	IEA	Interproscan predictions
MF	GO:0008234	cysteine-type peptidase activity	IEA	PlasmoDB
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0048583	regulation of response to stimulus	None	Extended
BP	GO:0050776	regulation of immune response	TAS	PlasmoDB
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
MF	GO:0000287	magnesium ion binding	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004656	procollagen-proline 4-dioxygenase activity	IEP	Predicted GO
MF	GO:0004722	protein serine/threonine phosphatase activity	IEP	Predicted GO
MF	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	IEP	Predicted GO
MF	GO:0005326	neurotransmitter transporter activity	IEP	Predicted GO
MF	GO:0005328	neurotransmitter:sodium symporter activity	IEP	Predicted GO
MF	GO:0005506	iron ion binding	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005886	plasma membrane	IEP	Predicted GO
CC	GO:0005955	calcineurin complex	IEP	Predicted GO
BP	GO:0006486	protein glycosylation	IEP	Predicted GO
BP	GO:0006836	neurotransmitter transport	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015293	symporter activity	IEP	Predicted GO
MF	GO:0015294	solute:cation symporter activity	IEP	Predicted GO
MF	GO:0015370	solute:sodium symporter activity	IEP	Predicted GO
MF	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	IEP	Predicted GO
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Predicted GO
MF	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	IEP	Predicted GO
BP	GO:0018103	protein C-linked glycosylation	IEP	Predicted GO
MF	GO:0019798	procollagen-proline dioxygenase activity	IEP	Predicted GO
MF	GO:0019842	vitamin binding	IEP	Predicted GO
CC	GO:0020003	symbiont-containing vacuole	IEP	Predicted GO
CC	GO:0020004	symbiont-containing vacuolar space	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0030246	carbohydrate binding	IEP	Predicted GO
CC	GO:0030430	host cell cytoplasm	IEP	Predicted GO
MF	GO:0031406	carboxylic acid binding	IEP	Predicted GO
MF	GO:0031418	L-ascorbic acid binding	IEP	Predicted GO
MF	GO:0031543	peptidyl-proline dioxygenase activity	IEP	Predicted GO
MF	GO:0031545	peptidyl-proline 4-dioxygenase activity	IEP	Predicted GO
CC	GO:0031965	nuclear membrane	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0033643	host cell part	IEP	Predicted GO
CC	GO:0033646	host intracellular part	IEP	Predicted GO
CC	GO:0033655	host cell cytoplasm part	IEP	Predicted GO
BP	GO:0035890	exit from host	IEP	Predicted GO
BP	GO:0035891	exit from host cell	IEP	Predicted GO
BP	GO:0040011	locomotion	IEP	Predicted GO
MF	GO:0043177	organic acid binding	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
BP	GO:0043413	macromolecule glycosylation	IEP	Predicted GO
MF	GO:0043495	protein membrane anchor	IEP	Predicted GO
CC	GO:0044217	other organism part	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
MF	GO:0048029	monosaccharide binding	IEP	Predicted GO
MF	GO:0051213	dioxygenase activity	IEP	Predicted GO
BP	GO:0052126	movement in host environment	IEP	Predicted GO
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	IEP	Predicted GO
CC	GO:0065010	extracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0070085	glycosylation	IEP	Predicted GO
BP	GO:0071344	diphosphate metabolic process	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000668	Peptidase_C1A_C	535	760

External Links

PlasmoDB	812672
PlasmoDB	PF02_0076
PlasmoDB	PFB0360c

PF3D7_0208000 (SERA1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation