PF3D7_0209300 (IspF)

Aliases : IspF

Description : SSF69765: "2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily". Pfam domain(s): PF02542: YgbB family.

Gene families : OG_01_0000559 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000559_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0209300
Cluster	P. falciparum: Cluster_43

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006720	isoprenoid metabolic process	None	Extended
BP	GO:0006721	terpenoid metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008299	isoprenoid biosynthetic process	None	Extended
BP	GO:0008610	lipid biosynthetic process	None	Extended
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEA	Interproscan predictions
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEA	PlasmoDB
BP	GO:0009058	biosynthetic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016114	terpenoid biosynthetic process	IEA	Interproscan predictions
BP	GO:0016114	terpenoid biosynthetic process	IEA	PlasmoDB
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016849	phosphorus-oxygen lyase activity	None	Extended
CC	GO:0020011	apicoplast	RCA	PlasmoDB
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000036	acyl carrier activity	IEP	Predicted GO
MF	GO:0000062	fatty-acyl-CoA binding	IEP	Predicted GO
MF	GO:0003714	transcription corepressor activity	IEP	Predicted GO
MF	GO:0003896	DNA primase activity	IEP	Predicted GO
MF	GO:0004000	adenosine deaminase activity	IEP	Predicted GO
MF	GO:0004045	aminoacyl-tRNA hydrolase activity	IEP	Predicted GO
MF	GO:0004144	diacylglycerol O-acyltransferase activity	IEP	Predicted GO
MF	GO:0004601	peroxidase activity	IEP	Predicted GO
MF	GO:0004602	glutathione peroxidase activity	IEP	Predicted GO
MF	GO:0005310	dicarboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005342	organic acid transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005787	signal peptidase complex	IEP	Predicted GO
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Predicted GO
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006449	regulation of translational termination	IEP	Predicted GO
BP	GO:0006452	translational frameshifting	IEP	Predicted GO
BP	GO:0006638	neutral lipid metabolic process	IEP	Predicted GO
BP	GO:0006639	acylglycerol metabolic process	IEP	Predicted GO
BP	GO:0006641	triglyceride metabolic process	IEP	Predicted GO
BP	GO:0006729	tetrahydrobiopterin biosynthetic process	IEP	Predicted GO
BP	GO:0006835	dicarboxylic acid transport	IEP	Predicted GO
MF	GO:0008081	phosphoric diester hydrolase activity	IEP	Predicted GO
MF	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008374	O-acyltransferase activity	IEP	Predicted GO
MF	GO:0008379	thioredoxin peroxidase activity	IEP	Predicted GO
MF	GO:0008509	anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008889	glycerophosphodiester phosphodiesterase activity	IEP	Predicted GO
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009891	positive regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0010557	positive regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010628	positive regulation of gene expression	IEP	Predicted GO
MF	GO:0015140	malate transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015367	oxoglutarate:malate antiporter activity	IEP	Predicted GO
MF	GO:0015556	C4-dicarboxylate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015740	C4-dicarboxylate transport	IEP	Predicted GO
BP	GO:0015742	alpha-ketoglutarate transport	IEP	Predicted GO
BP	GO:0015743	malate transport	IEP	Predicted GO
BP	GO:0015849	organic acid transport	IEP	Predicted GO
MF	GO:0016411	acylglycerol O-acyltransferase activity	IEP	Predicted GO
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Predicted GO
BP	GO:0017062	respiratory chain complex III assembly	IEP	Predicted GO
MF	GO:0019239	deaminase activity	IEP	Predicted GO
BP	GO:0019432	triglyceride biosynthetic process	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
BP	GO:0031325	positive regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031328	positive regulation of cellular biosynthetic process	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
BP	GO:0032259	methylation	IEP	Predicted GO
BP	GO:0032270	positive regulation of cellular protein metabolic process	IEP	Predicted GO
BP	GO:0033108	mitochondrial respiratory chain complex assembly	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0034250	positive regulation of cellular amide metabolic process	IEP	Predicted GO
BP	GO:0034311	diol metabolic process	IEP	Predicted GO
BP	GO:0034312	diol biosynthetic process	IEP	Predicted GO
BP	GO:0034551	mitochondrial respiratory chain complex III assembly	IEP	Predicted GO
MF	GO:0043021	ribonucleoprotein complex binding	IEP	Predicted GO
MF	GO:0043022	ribosome binding	IEP	Predicted GO
BP	GO:0043243	positive regulation of protein complex disassembly	IEP	Predicted GO
BP	GO:0043244	regulation of protein complex disassembly	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
MF	GO:0044620	ACP phosphopantetheine attachment site binding	IEP	Predicted GO
MF	GO:0044877	protein-containing complex binding	IEP	Predicted GO
BP	GO:0045727	positive regulation of translation	IEP	Predicted GO
BP	GO:0045901	positive regulation of translational elongation	IEP	Predicted GO
BP	GO:0045905	positive regulation of translational termination	IEP	Predicted GO
BP	GO:0046146	tetrahydrobiopterin metabolic process	IEP	Predicted GO
BP	GO:0046460	neutral lipid biosynthetic process	IEP	Predicted GO
BP	GO:0046463	acylglycerol biosynthetic process	IEP	Predicted GO
BP	GO:0046942	carboxylic acid transport	IEP	Predicted GO
MF	GO:0046943	carboxylic acid transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051131	chaperone-mediated protein complex assembly	IEP	Predicted GO
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051181	cofactor transport	IEP	Predicted GO
MF	GO:0051192	prosthetic group binding	IEP	Predicted GO
BP	GO:0051247	positive regulation of protein metabolic process	IEP	Predicted GO
MF	GO:0051920	peroxiredoxin activity	IEP	Predicted GO
MF	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity	IEP	Predicted GO
MF	GO:1901567	fatty acid derivative binding	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003526	MECDP_synthase	64	235

External Links

PlasmoDB	812685
PlasmoDB	PF02_0089
PlasmoDB	PFB0420w

PF3D7_0209300 (IspF)

Expression Profile

Co-expression Networks

Functional Annotation