PF3D7_0211700 (TKL1)

Aliases : TKL1

Description : SSF56112: Protein kinase-like domain superfamily, SSF47769: Sterile alpha motif/pointed domain superfamily. Pfam domain(s): PF00069: Protein kinase domain.

Gene families : OG_01_0002347 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002347_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0211700
Cluster	P. falciparum: Cluster_45

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	ISS	PlasmoDB
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	ISS	PlasmoDB
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000164	protein phosphatase type 1 complex	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003923	GPI-anchor transamidase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004823	leucine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004831	tyrosine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004839	ubiquitin activating enzyme activity	IEP	Predicted GO
MF	GO:0004857	enzyme inhibitor activity	IEP	Predicted GO
MF	GO:0004864	protein phosphatase inhibitor activity	IEP	Predicted GO
MF	GO:0004865	protein serine/threonine phosphatase inhibitor activity	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005658	alpha DNA polymerase:primase complex	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006427	histidyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006429	leucyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006437	tyrosyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0007154	cell communication	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
MF	GO:0009378	four-way junction helicase activity	IEP	Predicted GO
BP	GO:0009432	SOS response	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0010033	response to organic substance	IEP	Predicted GO
BP	GO:0010243	response to organonitrogen compound	IEP	Predicted GO
BP	GO:0010498	proteasomal protein catabolic process	IEP	Predicted GO
CC	GO:0016234	inclusion body	IEP	Predicted GO
BP	GO:0016255	attachment of GPI anchor to protein	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
BP	GO:0016925	protein sumoylation	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
MF	GO:0019212	phosphatase inhibitor activity	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
BP	GO:0019915	lipid storage	IEP	Predicted GO
MF	GO:0019948	SUMO activating enzyme activity	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
MF	GO:0030145	manganese ion binding	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
BP	GO:0030433	ubiquitin-dependent ERAD pathway	IEP	Predicted GO
CC	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	IEP	Predicted GO
BP	GO:0031668	cellular response to extracellular stimulus	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0034976	response to endoplasmic reticulum stress	IEP	Predicted GO
BP	GO:0036503	ERAD pathway	IEP	Predicted GO
BP	GO:0042391	regulation of membrane potential	IEP	Predicted GO
CC	GO:0042765	GPI-anchor transamidase complex	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0050515	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	IEP	Predicted GO
MF	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	IEP	Predicted GO
BP	GO:0051235	maintenance of location	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0051881	regulation of mitochondrial membrane potential	IEP	Predicted GO
BP	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	IEP	Predicted GO
BP	GO:0071496	cellular response to external stimulus	IEP	Predicted GO
BP	GO:0071897	DNA biosynthetic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901698	response to nitrogen compound	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000719	Prot_kinase_dom	952	1207

External Links

PlasmoDB	812705
PlasmoDB	PF02_0109
PlasmoDB	PFB0520w

PF3D7_0211700 (TKL1)

Expression Profile

Co-expression Networks

Functional Annotation