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  5. PF3D7_0306300

PF3D7_0306300 (GRX1)


Aliases : GRX1

Description : SSF52833: Thioredoxin-like superfamily. Pfam domain(s): PF00462: Glutaredoxin.


Gene families : OG_01_0000253 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000253_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0306300
Cluster P. falciparum: Cluster_48

Target Alias Description ECC score Gene Family Method Actions
PBANKA_0404700 GRX1 SSF52833: Thioredoxin-like superfamily. Pfam domain(s):... 0.04 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0009055 electron transfer activity IEA Interproscan predictions
MF GO:0009055 electron transfer activity IEA PlasmoDB
MF GO:0015035 protein disulfide oxidoreductase activity IEA Interproscan predictions
MF GO:0015035 protein disulfide oxidoreductase activity IEA PlasmoDB
MF GO:0016209 antioxidant activity IDA PlasmoDB
MF GO:0019153 protein-disulfide reductase (glutathione) activity IDA PlasmoDB
BP GO:0045454 cell redox homeostasis IEA Interproscan predictions
BP GO:0045454 cell redox homeostasis IEA PlasmoDB
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Type GO Term Name Evidence Source
MF GO:0000036 acyl carrier activity IEP Predicted GO
MF GO:0000062 fatty-acyl-CoA binding IEP Predicted GO
CC GO:0000151 ubiquitin ligase complex IEP Predicted GO
CC GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) IEP Predicted GO
MF GO:0000287 magnesium ion binding IEP Predicted GO
BP GO:0000380 alternative mRNA splicing, via spliceosome IEP Predicted GO
BP GO:0001678 cellular glucose homeostasis IEP Predicted GO
BP GO:0003006 developmental process involved in reproduction IEP Predicted GO
MF GO:0003725 double-stranded RNA binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003998 acylphosphatase activity IEP Predicted GO
MF GO:0004170 dUTP diphosphatase activity IEP Predicted GO
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity IEP Predicted GO
MF GO:0004396 hexokinase activity IEP Predicted GO
MF GO:0004550 nucleoside diphosphate kinase activity IEP Predicted GO
MF GO:0004601 peroxidase activity IEP Predicted GO
MF GO:0004693 cyclin-dependent protein serine/threonine kinase activity IEP Predicted GO
MF GO:0004731 purine-nucleoside phosphorylase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0004784 superoxide dismutase activity IEP Predicted GO
MF GO:0004807 triose-phosphate isomerase activity IEP Predicted GO
MF GO:0005102 signaling receptor binding IEP Predicted GO
MF GO:0005125 cytokine activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005253 anion channel activity IEP Predicted GO
MF GO:0005254 chloride channel activity IEP Predicted GO
MF GO:0005381 iron ion transmembrane transporter activity IEP Predicted GO
MF GO:0005536 glucose binding IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006006 glucose metabolic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006091 generation of precursor metabolites and energy IEP Predicted GO
BP GO:0006094 gluconeogenesis IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006148 inosine catabolic process IEP Predicted GO
BP GO:0006152 purine nucleoside catabolic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006183 GTP biosynthetic process IEP Predicted GO
BP GO:0006228 UTP biosynthetic process IEP Predicted GO
BP GO:0006241 CTP biosynthetic process IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006631 fatty acid metabolic process IEP Predicted GO
BP GO:0006633 fatty acid biosynthetic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006754 ATP biosynthetic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006801 superoxide metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006875 cellular metal ion homeostasis IEP Predicted GO
BP GO:0006879 cellular iron ion homeostasis IEP Predicted GO
BP GO:0006979 response to oxidative stress IEP Predicted GO
BP GO:0007154 cell communication IEP Predicted GO
BP GO:0007530 sex determination IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008379 thioredoxin peroxidase activity IEP Predicted GO
BP GO:0008380 RNA splicing IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009057 macromolecule catabolic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009119 ribonucleoside metabolic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009147 pyrimidine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009218 pyrimidine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009220 pyrimidine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015093 ferrous iron transmembrane transporter activity IEP Predicted GO
MF GO:0015103 inorganic anion transmembrane transporter activity IEP Predicted GO
MF GO:0015108 chloride transmembrane transporter activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
BP GO:0016051 carbohydrate biosynthetic process IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016684 oxidoreductase activity, acting on peroxide as acceptor IEP Predicted GO
MF GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor IEP Predicted GO
MF GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
CC GO:0019005 SCF ubiquitin ligase complex IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
BP GO:0019318 hexose metabolic process IEP Predicted GO
BP GO:0019319 hexose biosynthetic process IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019439 aromatic compound catabolic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
CC GO:0019773 proteasome core complex, alpha-subunit complex IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
BP GO:0020012 evasion or tolerance of host immune response IEP Predicted GO
BP GO:0022414 reproductive process IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
MF GO:0022804 active transmembrane transporter activity IEP Predicted GO
MF GO:0030246 carbohydrate binding IEP Predicted GO
MF GO:0030545 receptor regulator activity IEP Predicted GO
BP GO:0030682 evasion or tolerance of host defense response IEP Predicted GO
MF GO:0030955 potassium ion binding IEP Predicted GO
MF GO:0031404 chloride ion binding IEP Predicted GO
MF GO:0031420 alkali metal ion binding IEP Predicted GO
CC GO:0031461 cullin-RING ubiquitin ligase complex IEP Predicted GO
BP GO:0031668 cellular response to extracellular stimulus IEP Predicted GO
MF GO:0032552 deoxyribonucleotide binding IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033500 carbohydrate homeostasis IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034655 nucleobase-containing compound catabolic process IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
CC GO:0035145 exon-exon junction complex IEP Predicted GO
BP GO:0042262 DNA protection IEP Predicted GO
BP GO:0042278 purine nucleoside metabolic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0042593 glucose homeostasis IEP Predicted GO
MF GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
MF GO:0043492 ATPase activity, coupled to movement of substances IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
MF GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044265 cellular macromolecule catabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0044270 cellular nitrogen compound catabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
BP GO:0044413 avoidance of host defenses IEP Predicted GO
BP GO:0044415 evasion or tolerance of host defenses IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
MF GO:0044620 ACP phosphopantetheine attachment site binding IEP Predicted GO
BP GO:0045116 protein neddylation IEP Predicted GO
CC GO:0045269 proton-transporting ATP synthase, central stalk IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046036 CTP metabolic process IEP Predicted GO
BP GO:0046039 GTP metabolic process IEP Predicted GO
BP GO:0046051 UTP metabolic process IEP Predicted GO
BP GO:0046102 inosine metabolic process IEP Predicted GO
BP GO:0046128 purine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046130 purine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046364 monosaccharide biosynthetic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046434 organophosphate catabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046700 heterocycle catabolic process IEP Predicted GO
BP GO:0046916 cellular transition metal ion homeostasis IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
MF GO:0047429 nucleoside-triphosphate diphosphatase activity IEP Predicted GO
MF GO:0048018 receptor ligand activity IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
BP GO:0048878 chemical homeostasis IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
MF GO:0051192 prosthetic group binding IEP Predicted GO
BP GO:0051260 protein homooligomerization IEP Predicted GO
BP GO:0051262 protein tetramerization IEP Predicted GO
BP GO:0051289 protein homotetramerization IEP Predicted GO
BP GO:0051382 kinetochore assembly IEP Predicted GO
BP GO:0051383 kinetochore organization IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
MF GO:0051920 peroxiredoxin activity IEP Predicted GO
BP GO:0052200 response to host defenses IEP Predicted GO
BP GO:0052572 response to host immune response IEP Predicted GO
BP GO:0055072 iron ion homeostasis IEP Predicted GO
BP GO:0055076 transition metal ion homeostasis IEP Predicted GO
BP GO:0055082 cellular chemical homeostasis IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0071496 cellular response to external stimulus IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
MF GO:0072509 divalent inorganic cation transmembrane transporter activity IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072523 purine-containing compound catabolic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072593 reactive oxygen species metabolic process IEP Predicted GO
BP GO:0075136 response to host IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
MF GO:0097472 cyclin-dependent protein kinase activity IEP Predicted GO
CC GO:0098798 mitochondrial protein complex IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:0140104 molecular carrier activity IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901361 organic cyclic compound catabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
MF GO:1901567 fatty acid derivative binding IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
CC GO:1990234 transferase complex IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR002109 Glutaredoxin 21 85
PlasmoDB 814381
PlasmoDB PFC0271c