PF3D7_0316300 (PPase)

Aliases : PPase

Description : SSF50324: Inorganic pyrophosphatase superfamily. Pfam domain(s): PF00719: Inorganic pyrophosphatase.

Gene families : OG_01_0000645 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000645_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0316300
Cluster	P. falciparum: Cluster_17

Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEA	Interproscan predictions
MF	GO:0000287	magnesium ion binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004427	inorganic diphosphatase activity	IEA	Interproscan predictions
MF	GO:0004427	inorganic diphosphatase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	Interproscan predictions
CC	GO:0005737	cytoplasm	IEA	PlasmoDB
CC	GO:0005829	cytosol	IDA	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	IEA	Interproscan predictions
BP	GO:0006796	phosphate-containing compound metabolic process	IEA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0071344	diphosphate metabolic process	IDA	PlasmoDB
BP	GO:0071704	organic substance metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000502	proteasome complex	IEP	Predicted GO
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
BP	GO:0002376	immune system process	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
MF	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	IEP	Predicted GO
MF	GO:0005388	calcium-transporting ATPase activity	IEP	Predicted GO
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005838	proteasome regulatory particle	IEP	Predicted GO
BP	GO:0006103	2-oxoglutarate metabolic process	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006410	obsolete transcription, RNA-dependent	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006816	calcium ion transport	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0007029	endoplasmic reticulum organization	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
MF	GO:0008375	acetylglucosaminyltransferase activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
CC	GO:0009368	endopeptidase Clp complex	IEP	Predicted GO
BP	GO:0009894	regulation of catabolic process	IEP	Predicted GO
BP	GO:0015074	DNA integration	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	IEP	Predicted GO
MF	GO:0016018	cyclosporin A binding	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	IEP	Predicted GO
BP	GO:0018143	nucleic acid-protein covalent cross-linking	IEP	Predicted GO
BP	GO:0018144	RNA-protein covalent cross-linking	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0020003	symbiont-containing vacuole	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Predicted GO
MF	GO:0031079	obsolete picornain 3C activity	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0034212	peptide N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0035890	exit from host	IEP	Predicted GO
BP	GO:0035891	exit from host cell	IEP	Predicted GO
BP	GO:0040011	locomotion	IEP	Predicted GO
BP	GO:0042176	regulation of protein catabolic process	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
MF	GO:0043495	protein membrane anchor	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
MF	GO:0048256	flap endonuclease activity	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
BP	GO:0050789	regulation of biological process	IEP	Predicted GO
BP	GO:0051246	regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0052126	movement in host environment	IEP	Predicted GO
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	IEP	Predicted GO
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
CC	GO:0065010	extracellular membrane-bounded organelle	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
CC	GO:0071782	endoplasmic reticulum tubular network	IEP	Predicted GO
BP	GO:0071786	endoplasmic reticulum tubular network organization	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
CC	GO:0098827	endoplasmic reticulum subcompartment	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR008162	Pyrophosphatase	125	307
IPR008162	Pyrophosphatase	556	738

External Links

PlasmoDB	MAL3P6.3
PlasmoDB	PFC0710w

PF3D7_0316300 (PPase)

Expression Profile

Co-expression Networks

Functional Annotation