PF3D7_0319100 (RBX1)

Aliases : RBX1

Description : SSF57850: No description available. Pfam domain(s): PF12678: RING-H2 zinc finger domain.

Gene families : OG_01_0000955 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000955_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0319100
Cluster	P. falciparum: Cluster_46

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0806200	RBX1	SSF57850: 20-02-2019. Pfam domain(s): PF12678: RING-H2...	0.06	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	ISS	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004842	ubiquitin-protein transferase activity	ISS	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan predictions
MF	GO:0008270	zinc ion binding	IEA	PlasmoDB
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019787	ubiquitin-like protein transferase activity	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0000182	rDNA binding	IEP	Predicted GO
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
CC	GO:0000786	nucleosome	IEP	Predicted GO
CC	GO:0000791	euchromatin	IEP	Predicted GO
BP	GO:0003006	developmental process involved in reproduction	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0003998	acylphosphatase activity	IEP	Predicted GO
MF	GO:0004013	adenosylhomocysteinase activity	IEP	Predicted GO
MF	GO:0004170	dUTP diphosphatase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004392	heme oxygenase (decyclizing) activity	IEP	Predicted GO
MF	GO:0004550	nucleoside diphosphate kinase activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004776	succinate-CoA ligase (GDP-forming) activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005680	anaphase-promoting complex	IEP	Predicted GO
CC	GO:0005682	U5 snRNP	IEP	Predicted GO
CC	GO:0005685	U1 snRNP	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005740	mitochondrial envelope	IEP	Predicted GO
CC	GO:0005763	mitochondrial small ribosomal subunit	IEP	Predicted GO
CC	GO:0005784	Sec61 translocon complex	IEP	Predicted GO
CC	GO:0005813	centrosome	IEP	Predicted GO
CC	GO:0005815	microtubule organizing center	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
BP	GO:0006099	tricarboxylic acid cycle	IEP	Predicted GO
BP	GO:0006101	citrate metabolic process	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006108	malate metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Predicted GO
BP	GO:0006183	GTP biosynthetic process	IEP	Predicted GO
BP	GO:0006228	UTP biosynthetic process	IEP	Predicted GO
BP	GO:0006241	CTP biosynthetic process	IEP	Predicted GO
BP	GO:0006325	chromatin organization	IEP	Predicted GO
BP	GO:0006333	chromatin assembly or disassembly	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006458	'de novo' protein folding	IEP	Predicted GO
BP	GO:0006662	glycerol ether metabolic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006754	ATP biosynthetic process	IEP	Predicted GO
BP	GO:0006787	porphyrin-containing compound catabolic process	IEP	Predicted GO
BP	GO:0006848	pyruvate transport	IEP	Predicted GO
BP	GO:0006850	mitochondrial pyruvate transmembrane transport	IEP	Predicted GO
BP	GO:0007530	sex determination	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009891	positive regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009894	regulation of catabolic process	IEP	Predicted GO
BP	GO:0010557	positive regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010628	positive regulation of gene expression	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
BP	GO:0015074	DNA integration	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016615	malate dehydrogenase activity	IEP	Predicted GO
MF	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	IEP	Predicted GO
MF	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Predicted GO
MF	GO:0016801	hydrolase activity, acting on ether bonds	IEP	Predicted GO
MF	GO:0016802	trialkylsulfonium hydrolase activity	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
BP	GO:0016999	antibiotic metabolic process	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
BP	GO:0018904	ether metabolic process	IEP	Predicted GO
CC	GO:0019005	SCF ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0019153	protein-disulfide reductase (glutathione) activity	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0022414	reproductive process	IEP	Predicted GO
MF	GO:0030060	L-malate dehydrogenase activity	IEP	Predicted GO
CC	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
BP	GO:0031325	positive regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031328	positive regulation of cellular biosynthetic process	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0031965	nuclear membrane	IEP	Predicted GO
CC	GO:0031967	organelle envelope	IEP	Predicted GO
CC	GO:0031975	envelope	IEP	Predicted GO
MF	GO:0032552	deoxyribonucleotide binding	IEP	Predicted GO
BP	GO:0032784	regulation of DNA-templated transcription, elongation	IEP	Predicted GO
BP	GO:0032786	positive regulation of DNA-templated transcription, elongation	IEP	Predicted GO
CC	GO:0032993	protein-DNA complex	IEP	Predicted GO
BP	GO:0033015	tetrapyrrole catabolic process	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
CC	GO:0035145	exon-exon junction complex	IEP	Predicted GO
BP	GO:0042167	heme catabolic process	IEP	Predicted GO
BP	GO:0042176	regulation of protein catabolic process	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
CC	GO:0042709	succinate-CoA ligase complex	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044815	DNA packaging complex	IEP	Predicted GO
BP	GO:0045116	protein neddylation	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045244	succinate-CoA ligase complex (GDP-forming)	IEP	Predicted GO
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Predicted GO
BP	GO:0045893	positive regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0045935	positive regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0046036	CTP metabolic process	IEP	Predicted GO
BP	GO:0046039	GTP metabolic process	IEP	Predicted GO
BP	GO:0046051	UTP metabolic process	IEP	Predicted GO
BP	GO:0046149	pigment catabolic process	IEP	Predicted GO
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0046939	nucleotide phosphorylation	IEP	Predicted GO
MF	GO:0046982	protein heterodimerization activity	IEP	Predicted GO
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Predicted GO
MF	GO:0050833	pyruvate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051187	cofactor catabolic process	IEP	Predicted GO
BP	GO:0051254	positive regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0055074	calcium ion homeostasis	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
CC	GO:0070971	endoplasmic reticulum exit site	IEP	Predicted GO
CC	GO:0071256	translocon complex	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0072507	divalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901475	pyruvate transmembrane transport	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1902680	positive regulation of RNA biosynthetic process	IEP	Predicted GO
BP	GO:1903508	positive regulation of nucleic acid-templated transcription	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR024766	Znf_RING_H2	31	97

External Links

PlasmoDB	814505
PlasmoDB	MAL3P6.28
PlasmoDB	PFC0845c

PF3D7_0319100 (RBX1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation