PF3D7_0409400 (DnaJ)

Aliases : DnaJ

Description : SSF49493: HSP40/DnaJ peptide-binding, SSF57938: "Heat shock protein DnaJ, cysteine-rich domain superfamily", SSF46565: Chaperone J-domain superfamily. Pfam domain(s): PF00684: DnaJ central domain, PF01556: DnaJ C terminal domain, PF00226: DnaJ domain.

Gene families : OG_01_0001224 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001224_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0409400
Cluster	P. falciparum: Cluster_38

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1007000	No alias	SSF46565: Chaperone J-domain superfamily, SSF57938: Heat...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IDA	PlasmoDB
MF	GO:0003688	DNA replication origin binding	IDA	PlasmoDB
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006457	protein folding	IEA	PlasmoDB
BP	GO:0006950	response to stress	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009266	response to temperature stimulus	None	Extended
BP	GO:0009408	response to heat	TAS	PlasmoDB
CC	GO:0009536	plastid	None	Extended
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
MF	GO:0031072	heat shock protein binding	IEA	Interproscan predictions
MF	GO:0031072	heat shock protein binding	IEA	PlasmoDB
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
MF	GO:0043565	sequence-specific DNA binding	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0051082	unfolded protein binding	TAS	PlasmoDB
MF	GO:0051082	unfolded protein binding	IEA	Interproscan predictions
MF	GO:0051082	unfolded protein binding	IEA	PlasmoDB
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
MF	GO:1990837	sequence-specific double-stranded DNA binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000054	ribosomal subunit export from nucleus	IEP	Predicted GO
BP	GO:0000055	ribosomal large subunit export from nucleus	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEP	Predicted GO
BP	GO:0001510	RNA methylation	IEP	Predicted GO
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0003883	CTP synthase activity	IEP	Predicted GO
MF	GO:0004019	adenylosuccinate synthase activity	IEP	Predicted GO
MF	GO:0004152	dihydroorotate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004164	diphthine synthase activity	IEP	Predicted GO
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004364	glutathione transferase activity	IEP	Predicted GO
MF	GO:0004588	orotate phosphoribosyltransferase activity	IEP	Predicted GO
MF	GO:0004651	polynucleotide 5'-phosphatase activity	IEP	Predicted GO
MF	GO:0004735	pyrroline-5-carboxylate reductase activity	IEP	Predicted GO
MF	GO:0004743	pyruvate kinase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004815	aspartate-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004822	isoleucine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004832	valine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005666	RNA polymerase III complex	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005832	chaperonin-containing T-complex	IEP	Predicted GO
CC	GO:0005854	nascent polypeptide-associated complex	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006096	glycolytic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006167	AMP biosynthetic process	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006422	aspartyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006428	isoleucyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006560	proline metabolic process	IEP	Predicted GO
BP	GO:0006561	proline biosynthetic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006757	ATP generation from ADP	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006839	mitochondrial transport	IEP	Predicted GO
BP	GO:0006863	purine nucleobase transport	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008175	tRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0008649	rRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009304	tRNA transcription	IEP	Predicted GO
MF	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
BP	GO:0015851	nucleobase transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
CC	GO:0015935	small ribosomal subunit	IEP	Predicted GO
BP	GO:0016052	carbohydrate catabolic process	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016426	tRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0016434	rRNA (cytosine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016763	transferase activity, transferring pentosyl groups	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predicted GO
BP	GO:0030488	tRNA methylation	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0030687	preribosome, large subunit precursor	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
BP	GO:0032238	adenosine transport	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
MF	GO:0033678	5'-3' DNA/RNA helicase activity	IEP	Predicted GO
BP	GO:0033750	ribosome localization	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
CC	GO:0034708	methyltransferase complex	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042273	ribosomal large subunit biogenesis	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
BP	GO:0042797	tRNA transcription by RNA polymerase III	IEP	Predicted GO
MF	GO:0042802	identical protein binding	IEP	Predicted GO
MF	GO:0042803	protein homodimerization activity	IEP	Predicted GO
BP	GO:0042866	pyruvate biosynthetic process	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043414	macromolecule methylation	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
CC	GO:0043527	tRNA methyltransferase complex	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
BP	GO:0046031	ADP metabolic process	IEP	Predicted GO
BP	GO:0046033	AMP metabolic process	IEP	Predicted GO
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Predicted GO
MF	GO:0046403	polynucleotide 3'-phosphatase activity	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
BP	GO:0051656	establishment of organelle localization	IEP	Predicted GO
MF	GO:0051879	Hsp90 protein binding	IEP	Predicted GO
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
MF	GO:0070037	rRNA (pseudouridine) methyltransferase activity	IEP	Predicted GO
CC	GO:0070545	PeBoW complex	IEP	Predicted GO
BP	GO:0070585	protein localization to mitochondrion	IEP	Predicted GO
BP	GO:0071426	ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072655	establishment of protein localization to mitochondrion	IEP	Predicted GO
MF	GO:0098518	polynucleotide phosphatase activity	IEP	Predicted GO
BP	GO:0098781	ncRNA transcription	IEP	Predicted GO
CC	GO:0101031	chaperone complex	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001623	DnaJ_domain	61	122
IPR001305	HSP_DnaJ_Cys-rich_dom	204	264
IPR002939	DnaJ_C	177	390

External Links

PlasmoDB	812401
PlasmoDB	MAL4P2.30
PlasmoDB	PFD0462w
PlasmoDB	PFD0465w

PF3D7_0409400 (DnaJ)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation