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  5. PF3D7_0501800

PF3D7_0501800 (CAF1)


Aliases : CAF1

Description : SSF50978: WD40-repeat-containing domain superfamily. Pfam domain(s): PF00400: "WD domain, G-beta repeat".


Gene families : OG_01_0001366 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001366_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0501800
Cluster P. falciparum: Cluster_31

Target Alias Description ECC score Gene Family Method Actions
PBANKA_1101600 CAF1 SSF50978: WD40-repeat-containing domain superfamily.... 0.13 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IPI PlasmoDB
MF GO:0005515 protein binding IEA Interproscan predictions
MF GO:0005515 protein binding IEA PlasmoDB
CC GO:0005634 nucleus IDA PlasmoDB
MF GO:0042393 histone binding IDA PlasmoDB
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Type GO Term Name Evidence Source
BP GO:0000041 transition metal ion transport IEP Predicted GO
BP GO:0000075 cell cycle checkpoint IEP Predicted GO
BP GO:0000076 DNA replication checkpoint IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0002376 immune system process IEP Predicted GO
BP GO:0002377 immunoglobulin production IEP Predicted GO
BP GO:0002440 production of molecular mediator of immune response IEP Predicted GO
BP GO:0002682 regulation of immune system process IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0003689 DNA clamp loader activity IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0003916 DNA topoisomerase activity IEP Predicted GO
MF GO:0003917 DNA topoisomerase type I activity IEP Predicted GO
MF GO:0004176 ATP-dependent peptidase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0004529 exodeoxyribonuclease activity IEP Predicted GO
MF GO:0004536 deoxyribonuclease activity IEP Predicted GO
MF GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEP Predicted GO
MF GO:0004844 uracil DNA N-glycosylase activity IEP Predicted GO
MF GO:0005385 zinc ion transmembrane transporter activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005657 replication fork IEP Predicted GO
CC GO:0005663 DNA replication factor C complex IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
CC GO:0005971 ribonucleoside-diphosphate reductase complex IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006260 DNA replication IEP Predicted GO
BP GO:0006265 DNA topological change IEP Predicted GO
BP GO:0006268 DNA unwinding involved in DNA replication IEP Predicted GO
BP GO:0006270 DNA replication initiation IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006284 base-excision repair IEP Predicted GO
BP GO:0006497 protein lipidation IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006829 zinc ion transport IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
MF GO:0008094 DNA-dependent ATPase activity IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008296 3'-5'-exodeoxyribonuclease activity IEP Predicted GO
MF GO:0008297 single-stranded DNA exodeoxyribonuclease activity IEP Predicted GO
MF GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009262 deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009263 deoxyribonucleotide biosynthetic process IEP Predicted GO
CC GO:0009536 plastid IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010639 negative regulation of organelle organization IEP Predicted GO
BP GO:0015074 DNA integration IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
MF GO:0016208 AMP binding IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Predicted GO
MF GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
MF GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0019104 DNA N-glycosylase activity IEP Predicted GO
CC GO:0020011 apicoplast IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
BP GO:0031570 DNA integrity checkpoint IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033044 regulation of chromosome organization IEP Predicted GO
MF GO:0033170 protein-DNA loading ATPase activity IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
CC GO:0042555 MCM complex IEP Predicted GO
CC GO:0042575 DNA polymerase complex IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
BP GO:0043086 negative regulation of catalytic activity IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043625 delta DNA polymerase complex IEP Predicted GO
BP GO:0044092 negative regulation of molecular function IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
CC GO:0044427 chromosomal part IEP Predicted GO
BP GO:0045786 negative regulation of cell cycle IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
MF GO:0046915 transition metal ion transmembrane transporter activity IEP Predicted GO
MF GO:0048256 flap endonuclease activity IEP Predicted GO
BP GO:0048519 negative regulation of biological process IEP Predicted GO
BP GO:0048523 negative regulation of cellular process IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
BP GO:0050776 regulation of immune response IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051095 regulation of helicase activity IEP Predicted GO
BP GO:0051097 negative regulation of helicase activity IEP Predicted GO
BP GO:0051129 negative regulation of cellular component organization IEP Predicted GO
BP GO:0051276 chromosome organization IEP Predicted GO
BP GO:0051346 negative regulation of hydrolase activity IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
BP GO:0051726 regulation of cell cycle IEP Predicted GO
MF GO:0061731 ribonucleoside-diphosphate reductase activity IEP Predicted GO
BP GO:0070838 divalent metal ion transport IEP Predicted GO
BP GO:0071103 DNA conformation change IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
MF GO:0072509 divalent inorganic cation transmembrane transporter activity IEP Predicted GO
BP GO:0072511 divalent inorganic cation transport IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0097506 deaminated base DNA N-glycosylase activity IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1905462 regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905463 negative regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905774 regulation of DNA helicase activity IEP Predicted GO
BP GO:1905775 negative regulation of DNA helicase activity IEP Predicted GO
BP GO:2001251 negative regulation of chromosome organization IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 221 257
IPR001680 WD40_repeat 325 361
PlasmoDB 812866
PlasmoDB MAL5P1.19
PlasmoDB PFE0090w