PF3D7_0506900 (ROM4)

Aliases : ROM4

Description : SSF144091: No description available. Pfam domain(s): PF01694: Rhomboid family.

Gene families : OG_01_0000330 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000330_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0506900
Cluster	P. falciparum: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1106500	ROM4	SSF144091: 20-02-2019. Pfam domain(s): PF01694: Rhomboid family.	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004252	serine-type endopeptidase activity	IEA	Interproscan predictions
MF	GO:0004252	serine-type endopeptidase activity	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005886	plasma membrane	IDA	PlasmoDB
BP	GO:0006465	signal peptide processing	IDA	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006518	peptide metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008233	peptidase activity	IDA	PlasmoDB
MF	GO:0008236	serine-type peptidase activity	None	Extended
CC	GO:0009986	cell surface	RCA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
CC	GO:0016020	membrane	None	Extended
CC	GO:0016021	integral component of membrane	IEA	Interproscan predictions
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
BP	GO:0016485	protein processing	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0017171	serine hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051604	protein maturation	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0004103	choline kinase activity	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0005096	GTPase activator activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
CC	GO:0005884	actin filament	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006656	phosphatidylcholine biosynthetic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0007264	small GTPase mediated signal transduction	IEP	Predicted GO
BP	GO:0007265	Ras protein signal transduction	IEP	Predicted GO
BP	GO:0007266	Rho protein signal transduction	IEP	Predicted GO
MF	GO:0008047	enzyme activator activity	IEP	Predicted GO
BP	GO:0008064	regulation of actin polymerization or depolymerization	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0009931	calcium-dependent protein serine/threonine kinase activity	IEP	Predicted GO
BP	GO:0010639	negative regulation of organelle organization	IEP	Predicted GO
MF	GO:0010857	calcium-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
BP	GO:0030029	actin filament-based process	IEP	Predicted GO
BP	GO:0030036	actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
MF	GO:0030695	GTPase regulator activity	IEP	Predicted GO
BP	GO:0030832	regulation of actin filament length	IEP	Predicted GO
BP	GO:0030833	regulation of actin filament polymerization	IEP	Predicted GO
BP	GO:0030837	negative regulation of actin filament polymerization	IEP	Predicted GO
BP	GO:0031333	negative regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0032271	regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032272	negative regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032507	maintenance of protein location in cell	IEP	Predicted GO
BP	GO:0032535	regulation of cellular component size	IEP	Predicted GO
BP	GO:0032956	regulation of actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0032970	regulation of actin filament-based process	IEP	Predicted GO
MF	GO:0033265	choline binding	IEP	Predicted GO
BP	GO:0040011	locomotion	IEP	Predicted GO
MF	GO:0042165	neurotransmitter binding	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
CC	GO:0042643	actomyosin, actin portion	IEP	Predicted GO
BP	GO:0042989	sequestering of actin monomers	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
BP	GO:0043254	regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0044087	regulation of cellular component biogenesis	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
BP	GO:0045185	maintenance of protein location	IEP	Predicted GO
BP	GO:0046470	phosphatidylcholine metabolic process	IEP	Predicted GO
BP	GO:0051129	negative regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051235	maintenance of location	IEP	Predicted GO
BP	GO:0051493	regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0051494	negative regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0051651	maintenance of location in cell	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
MF	GO:0070064	proline-rich region binding	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
MF	GO:0070405	ammonium ion binding	IEP	Predicted GO
BP	GO:0090066	regulation of anatomical structure size	IEP	Predicted GO
BP	GO:0097164	ammonium ion metabolic process	IEP	Predicted GO
BP	GO:0110053	regulation of actin filament organization	IEP	Predicted GO
BP	GO:1902903	regulation of supramolecular fiber organization	IEP	Predicted GO
BP	GO:1902904	negative regulation of supramolecular fiber organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR022764	Peptidase_S54_rhomboid_dom	455	591

External Links

PlasmoDB	812885
PlasmoDB	MAL5P1.70
PlasmoDB	PFE0340c

PF3D7_0506900 (ROM4)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation