PF3D7_0507100 (RPL4)

Aliases : RPL4

Description : SSF52166: Ribosomal protein L4 domain superfamily. Pfam domain(s): PF00573: Ribosomal protein L4/L1 family, PF14374: 60S ribosomal protein L4 C-terminal domain.

Gene families : OG_01_0001388 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001388_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0507100
Cluster	P. falciparum: Cluster_11

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1106700	RPL4	SSF52166: Ribosomal protein L4 domain superfamily. Pfam...	0.15	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003735	structural constituent of ribosome	IDA	PlasmoDB
MF	GO:0003735	structural constituent of ribosome	IEA	Interproscan predictions
MF	GO:0003735	structural constituent of ribosome	IEA	PlasmoDB
MF	GO:0005198	structural molecule activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005840	ribosome	IEA	Interproscan predictions
CC	GO:0005840	ribosome	IEA	PlasmoDB
BP	GO:0006412	translation	ISS	PlasmoDB
BP	GO:0006412	translation	IEA	Interproscan predictions
BP	GO:0006412	translation	IEA	PlasmoDB
BP	GO:0006518	peptide metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0015934	large ribosomal subunit	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0022625	cytosolic large ribosomal subunit	IDA	PlasmoDB
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043043	peptide biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0043604	amide biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
CC	GO:0044391	ribosomal subunit	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044445	cytosolic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
CC	GO:1990904	ribonucleoprotein complex	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000302	response to reactive oxygen species	IEP	Predicted GO
BP	GO:0000304	response to singlet oxygen	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
BP	GO:0002181	cytoplasmic translation	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0003872	6-phosphofructokinase activity	IEP	Predicted GO
MF	GO:0003938	IMP dehydrogenase activity	IEP	Predicted GO
MF	GO:0004359	glutaminase activity	IEP	Predicted GO
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Predicted GO
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Predicted GO
MF	GO:0004827	proline-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005832	chaperonin-containing T-complex	IEP	Predicted GO
CC	GO:0005854	nascent polypeptide-associated complex	IEP	Predicted GO
BP	GO:0006002	fructose 6-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006090	pyruvate metabolic process	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006096	glycolytic process	IEP	Predicted GO
BP	GO:0006109	regulation of carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Predicted GO
BP	GO:0006166	purine ribonucleoside salvage	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006433	prolyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006458	'de novo' protein folding	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006733	oxidoreduction coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006754	ATP biosynthetic process	IEP	Predicted GO
BP	GO:0006757	ATP generation from ADP	IEP	Predicted GO
BP	GO:0007584	response to nutrient	IEP	Predicted GO
MF	GO:0008097	5S rRNA binding	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008419	RNA lariat debranching enzyme activity	IEP	Predicted GO
MF	GO:0008443	phosphofructokinase activity	IEP	Predicted GO
BP	GO:0008614	pyridoxine metabolic process	IEP	Predicted GO
BP	GO:0008615	pyridoxine biosynthetic process	IEP	Predicted GO
BP	GO:0009108	coenzyme biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009166	nucleotide catabolic process	IEP	Predicted GO
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0010035	response to inorganic substance	IEP	Predicted GO
BP	GO:0010322	regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0010323	negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0010563	negative regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0010565	regulation of cellular ketone metabolic process	IEP	Predicted GO
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0010677	negative regulation of cellular carbohydrate metabolic process	IEP	Predicted GO
CC	GO:0015935	small ribosomal subunit	IEP	Predicted GO
BP	GO:0016052	carbohydrate catabolic process	IEP	Predicted GO
MF	GO:0016778	diphosphotransferase activity	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
MF	GO:0019203	carbohydrate phosphatase activity	IEP	Predicted GO
BP	GO:0019216	regulation of lipid metabolic process	IEP	Predicted GO
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019747	regulation of isoprenoid metabolic process	IEP	Predicted GO
MF	GO:0019843	rRNA binding	IEP	Predicted GO
CC	GO:0022627	cytosolic small ribosomal subunit	IEP	Predicted GO
MF	GO:0030621	U4 snRNA binding	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Predicted GO
MF	GO:0034511	U3 snoRNA binding	IEP	Predicted GO
BP	GO:0042816	vitamin B6 metabolic process	IEP	Predicted GO
BP	GO:0042819	vitamin B6 biosynthetic process	IEP	Predicted GO
BP	GO:0042822	pyridoxal phosphate metabolic process	IEP	Predicted GO
BP	GO:0042823	pyridoxal phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0042866	pyruvate biosynthetic process	IEP	Predicted GO
BP	GO:0043094	cellular metabolic compound salvage	IEP	Predicted GO
BP	GO:0043101	purine-containing compound salvage	IEP	Predicted GO
BP	GO:0043174	nucleoside salvage	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
BP	GO:0045827	negative regulation of isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0045833	negative regulation of lipid metabolic process	IEP	Predicted GO
BP	GO:0045912	negative regulation of carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0045936	negative regulation of phosphate metabolic process	IEP	Predicted GO
BP	GO:0046031	ADP metabolic process	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
BP	GO:0046184	aldehyde biosynthetic process	IEP	Predicted GO
BP	GO:0046434	organophosphate catabolic process	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
BP	GO:0046890	regulation of lipid biosynthetic process	IEP	Predicted GO
BP	GO:0046939	nucleotide phosphorylation	IEP	Predicted GO
MF	GO:0047334	diphosphate-fructose-6-phosphate 1-phosphotransferase activity	IEP	Predicted GO
MF	GO:0050308	sugar-phosphatase activity	IEP	Predicted GO
BP	GO:0051055	negative regulation of lipid biosynthetic process	IEP	Predicted GO
BP	GO:0051083	'de novo' cotranslational protein folding	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051188	cofactor biosynthetic process	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0062012	regulation of small molecule metabolic process	IEP	Predicted GO
BP	GO:0062014	negative regulation of small molecule metabolic process	IEP	Predicted GO
BP	GO:0071071	regulation of phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0071072	negative regulation of phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
CC	GO:0101031	chaperone complex	IEP	Predicted GO
BP	GO:1901292	nucleoside phosphate catabolic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
BP	GO:1901700	response to oxygen-containing compound	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
BP	GO:1903725	regulation of phospholipid metabolic process	IEP	Predicted GO
BP	GO:1903726	negative regulation of phospholipid metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002136	Ribosomal_L4/L1e	23	261
IPR025755	Ribos_L4_C_dom	275	345

External Links

PlasmoDB	812881
PlasmoDB	MAL5P1.72
PlasmoDB	PFE0350c

PF3D7_0507100 (RPL4)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation