PF3D7_0509800 (PI4K)

Aliases : PI4K

Description : SSF48371: Armadillo-type fold, SSF56112: Protein kinase-like domain superfamily. Pfam domain(s): PF00454: Phosphatidylinositol 3- and 4-kinase.

Gene families : OG_01_0000167 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000167_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0509800
Cluster	P. falciparum: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1109400	PI4K	SSF56112: Protein kinase-like domain superfamily,...	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004430	1-phosphatidylinositol 4-kinase activity	IGI	PlasmoDB
MF	GO:0005488	binding	IEA	PlasmoDB
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006644	phospholipid metabolic process	None	Extended
BP	GO:0006650	glycerophospholipid metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016301	kinase activity	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IDA	PlasmoDB
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0046486	glycerolipid metabolic process	None	Extended
BP	GO:0046488	phosphatidylinositol metabolic process	ISM	PlasmoDB
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0052742	phosphatidylinositol kinase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004683	calmodulin-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0004686	elongation factor-2 kinase activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
BP	GO:0006338	chromatin remodeling	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0007015	actin filament organization	IEP	Predicted GO
BP	GO:0008064	regulation of actin polymerization or depolymerization	IEP	Predicted GO
BP	GO:0010638	positive regulation of organelle organization	IEP	Predicted GO
MF	GO:0016307	phosphatidylinositol phosphate kinase activity	IEP	Predicted GO
MF	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	IEP	Predicted GO
CC	GO:0030126	COPI vesicle coat	IEP	Predicted GO
BP	GO:0030258	lipid modification	IEP	Predicted GO
MF	GO:0030306	ADP-ribosylation factor binding	IEP	Predicted GO
BP	GO:0030832	regulation of actin filament length	IEP	Predicted GO
BP	GO:0030833	regulation of actin filament polymerization	IEP	Predicted GO
BP	GO:0030838	positive regulation of actin filament polymerization	IEP	Predicted GO
MF	GO:0031267	small GTPase binding	IEP	Predicted GO
BP	GO:0031334	positive regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0032271	regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032273	positive regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032535	regulation of cellular component size	IEP	Predicted GO
BP	GO:0032956	regulation of actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0032970	regulation of actin filament-based process	IEP	Predicted GO
MF	GO:0035091	phosphatidylinositol binding	IEP	Predicted GO
BP	GO:0035690	cellular response to drug	IEP	Predicted GO
BP	GO:0043254	regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0044087	regulation of cellular component biogenesis	IEP	Predicted GO
BP	GO:0044089	positive regulation of cellular component biogenesis	IEP	Predicted GO
BP	GO:0045010	actin nucleation	IEP	Predicted GO
BP	GO:0046834	lipid phosphorylation	IEP	Predicted GO
BP	GO:0046839	phospholipid dephosphorylation	IEP	Predicted GO
BP	GO:0046854	phosphatidylinositol phosphorylation	IEP	Predicted GO
BP	GO:0046856	phosphatidylinositol dephosphorylation	IEP	Predicted GO
BP	GO:0048518	positive regulation of biological process	IEP	Predicted GO
BP	GO:0048522	positive regulation of cellular process	IEP	Predicted GO
BP	GO:0051130	positive regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051493	regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0051495	positive regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0070887	cellular response to chemical stimulus	IEP	Predicted GO
BP	GO:0090066	regulation of anatomical structure size	IEP	Predicted GO
BP	GO:0097435	supramolecular fiber organization	IEP	Predicted GO
BP	GO:0110053	regulation of actin filament organization	IEP	Predicted GO
BP	GO:1902903	regulation of supramolecular fiber organization	IEP	Predicted GO
BP	GO:1902905	positive regulation of supramolecular fiber organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000403	PI3/4_kinase_cat_dom	1305	1371
IPR000403	PI3/4_kinase_cat_dom	1385	1496

External Links

PlasmoDB	812838
PlasmoDB	MAL5P1.99
PlasmoDB	PFE0485w

PF3D7_0509800 (PI4K)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation