1. Home
  2. Species
  3. Plasmodium falciparum 3D7
  4. Sequence
  5. PF3D7_0510500

PF3D7_0510500 (TopoI)


Aliases : TopoI

Description : SSF56349: "DNA breaking-rejoining enzyme, catalytic core", SSF56741: "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily". Pfam domain(s): PF02919: "Eukaryotic DNA topoisomerase I, DNA binding fragment", PF01028: "Eukaryotic DNA topoisomerase I, catalytic core", PF14370: C-terminal topoisomerase domain.


Gene families : OG_01_0001401 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001401_tree

Sequence : coding (download), protein (download)


Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0510500
Cluster P. falciparum: Cluster_22

Target Alias Description ECC score Gene Family Method Actions
PBANKA_1110100 No alias SSF56741: DNA topoisomerase I, DNA binding,... 0.03 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA Interproscan predictions
MF GO:0003677 DNA binding IEA PlasmoDB
MF GO:0003917 DNA topoisomerase type I activity ISS PlasmoDB
MF GO:0003917 DNA topoisomerase type I activity IEA Interproscan predictions
MF GO:0003917 DNA topoisomerase type I activity IEA PlasmoDB
CC GO:0005634 nucleus RCA PlasmoDB
CC GO:0005694 chromosome IEA Interproscan predictions
CC GO:0005694 chromosome IEA PlasmoDB
BP GO:0006265 DNA topological change ISS PlasmoDB
BP GO:0006265 DNA topological change IEA Interproscan predictions
BP GO:0006265 DNA topological change IEA PlasmoDB
BP GO:0042493 response to drug IDA PlasmoDB
Toggle parental
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0000413 protein peptidyl-prolyl isomerization IEP Predicted GO
MF GO:0003689 DNA clamp loader activity IEP Predicted GO
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEP Predicted GO
MF GO:0004467 long-chain fatty acid-CoA ligase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005663 DNA replication factor C complex IEP Predicted GO
BP GO:0007155 cell adhesion IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0015645 fatty acid ligase activity IEP Predicted GO
MF GO:0016208 AMP binding IEP Predicted GO
MF GO:0016405 CoA-ligase activity IEP Predicted GO
MF GO:0016859 cis-trans isomerase activity IEP Predicted GO
MF GO:0016878 acid-thiol ligase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0018208 peptidyl-proline modification IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0033170 protein-DNA loading ATPase activity IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0042393 histone binding IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
InterPro domains Description Start Stop
IPR025834 TopoI_C_dom 771 839
IPR008336 TopoI_DNA-bd_euk 154 380
IPR013500 TopoI_cat_euk 383 724
PlasmoDB 812833
PlasmoDB MAL5P1.106
PlasmoDB PFE0520c