PF3D7_0516700

Description : SSF54001: Papain-like cysteine peptidase superfamily. Pfam domain(s): PF00443: Ubiquitin carboxyl-terminal hydrolase.

Gene families : OG_01_0002979 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002979_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0516700
Cluster	P. falciparum: Cluster_20

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	ISS	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016579	protein deubiquitination	ISS	PlasmoDB
BP	GO:0016579	protein deubiquitination	IEA	Interproscan predictions
BP	GO:0016579	protein deubiquitination	IEA	PlasmoDB
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019783	ubiquitin-like protein-specific protease activity	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEA	Interproscan predictions
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEA	PlasmoDB
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0070646	protein modification by small protein removal	None	Extended
BP	GO:0070647	protein modification by small protein conjugation or removal	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0101005	ubiquitinyl hydrolase activity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004143	diacylglycerol kinase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004438	phosphatidylinositol-3-phosphatase activity	IEP	Predicted GO
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
CC	GO:0005662	DNA replication factor A complex	IEP	Predicted GO
CC	GO:0005792	obsolete microsome	IEP	Predicted GO
CC	GO:0005905	clathrin-coated pit	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006650	glycerophospholipid metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006814	sodium ion transport	IEP	Predicted GO
BP	GO:0006892	post-Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006895	Golgi to endosome transport	IEP	Predicted GO
BP	GO:0006915	apoptotic process	IEP	Predicted GO
BP	GO:0007186	G protein-coupled receptor signaling pathway	IEP	Predicted GO
BP	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	IEP	Predicted GO
BP	GO:0008219	cell death	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008964	phosphoenolpyruvate carboxylase activity	IEP	Predicted GO
BP	GO:0012501	programmed cell death	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015298	solute:cation antiporter activity	IEP	Predicted GO
MF	GO:0015299	solute:proton antiporter activity	IEP	Predicted GO
BP	GO:0015672	monovalent inorganic cation transport	IEP	Predicted GO
BP	GO:0015977	carbon fixation	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
BP	GO:0016311	dephosphorylation	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
CC	GO:0030015	CCR4-NOT core complex	IEP	Predicted GO
CC	GO:0030119	AP-type membrane coat adaptor complex	IEP	Predicted GO
CC	GO:0030131	clathrin adaptor complex	IEP	Predicted GO
BP	GO:0030258	lipid modification	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
CC	GO:0031225	anchored component of membrane	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
MF	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	IEP	Predicted GO
MF	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	IEP	Predicted GO
MF	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
MF	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity	IEP	Predicted GO
MF	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	IEP	Predicted GO
CC	GO:0044164	host cell cytosol	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
BP	GO:0046486	glycerolipid metabolic process	IEP	Predicted GO
BP	GO:0046488	phosphatidylinositol metabolic process	IEP	Predicted GO
CC	GO:0046658	anchored component of plasma membrane	IEP	Predicted GO
BP	GO:0046839	phospholipid dephosphorylation	IEP	Predicted GO
BP	GO:0046856	phosphatidylinositol dephosphorylation	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO
MF	GO:0052744	phosphatidylinositol monophosphate phosphatase activity	IEP	Predicted GO
MF	GO:0052866	phosphatidylinositol phosphate phosphatase activity	IEP	Predicted GO
MF	GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1990225	rhoptry neck	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001394	Peptidase_C19_UCH	312	799
IPR001394	Peptidase_C19_UCH	867	1298

External Links

PlasmoDB	812982
PlasmoDB	MAL5P1.167
PlasmoDB	PFE0835w

PF3D7_0516700

Expression Profile

Co-expression Networks

Functional Annotation