PF3D7_0517400 (FACT-L)

Aliases : FACT-L

Description : SSF55920: Creatinase/aminopeptidase-like. Pfam domain(s): PF00557: Metallopeptidase family M24, PF08644: FACT complex subunit (SPT16/CDC68), PF14826: FACT complex subunit SPT16 N-terminal lobe domain, PF08512: Histone chaperone Rttp106-like.

Gene families : OG_01_0001688 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001688_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0517400
Cluster	P. falciparum: Cluster_30

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1232200	FACT-L	SSF55920: Creatinase/aminopeptidase-like. Pfam...	0.08	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISO	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006351	transcription, DNA-templated	ISS	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0032774	RNA biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:0097659	nucleic acid-templated transcription	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Predicted GO
CC	GO:0000109	nucleotide-excision repair complex	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000226	microtubule cytoskeleton organization	IEP	Predicted GO
BP	GO:0000255	allantoin metabolic process	IEP	Predicted GO
BP	GO:0000256	allantoin catabolic process	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
MF	GO:0003674	molecular_function	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0004037	allantoicase activity	IEP	Predicted GO
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Predicted GO
MF	GO:0005201	extracellular matrix structural constituent	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005507	copper ion binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005581	collagen trimer	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
CC	GO:0005874	microtubule	IEP	Predicted GO
CC	GO:0005971	ribonucleoside-diphosphate reductase complex	IEP	Predicted GO
BP	GO:0006144	purine nucleobase metabolic process	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006825	copper ion transport	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
BP	GO:0009112	nucleobase metabolic process	IEP	Predicted GO
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Predicted GO
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
CC	GO:0030124	AP-4 adaptor complex	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
BP	GO:0042737	drug catabolic process	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043605	cellular amide catabolic process	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
BP	GO:0051028	mRNA transport	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
CC	GO:0099080	supramolecular complex	IEP	Predicted GO
CC	GO:0099081	supramolecular polymer	IEP	Predicted GO
CC	GO:0099512	supramolecular fiber	IEP	Predicted GO
CC	GO:0099513	polymeric cytoskeletal fiber	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
CC	GO:1990391	DNA repair complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000994	Pept_M24	222	415
IPR013953	FACT_Spt16	646	802
IPR029148	FACT-Spt16_Nlobe	5	159
IPR013719	DUF1747	928	1009

External Links

PlasmoDB	812989
PlasmoDB	MAL5P1.174
PlasmoDB	PFE0870w

PF3D7_0517400 (FACT-L)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation