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  5. PF3D7_0520600

PF3D7_0520600 (Ap4AH)


Aliases : Ap4AH

Description : SSF55811: NUDIX hydrolase-like domain superfamily. Pfam domain(s): PF00293: NUDIX domain.


Gene families : OG_01_0001703 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001703_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0520600
Cluster P. falciparum: Cluster_35


Type GO Term Name Evidence Source
MF GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity IDA PlasmoDB
MF GO:0016787 hydrolase activity IEA Interproscan predictions
MF GO:0016787 hydrolase activity IEA PlasmoDB
CC GO:0033644 host cell membrane IDA PlasmoDB
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Type GO Term Name Evidence Source
CC GO:0000323 lytic vacuole IEP Predicted GO
MF GO:0000339 RNA cap binding IEP Predicted GO
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predicted GO
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predicted GO
BP GO:0000380 alternative mRNA splicing, via spliceosome IEP Predicted GO
BP GO:0000398 mRNA splicing, via spliceosome IEP Predicted GO
CC GO:0000408 EKC/KEOPS complex IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003727 single-stranded RNA binding IEP Predicted GO
MF GO:0003729 mRNA binding IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0003921 GMP synthase activity IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0003938 IMP dehydrogenase activity IEP Predicted GO
MF GO:0004190 aspartic-type endopeptidase activity IEP Predicted GO
MF GO:0004356 glutamate-ammonia ligase activity IEP Predicted GO
MF GO:0004427 inorganic diphosphatase activity IEP Predicted GO
MF GO:0005381 iron ion transmembrane transporter activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
CC GO:0005732 small nucleolar ribonucleoprotein complex IEP Predicted GO
CC GO:0005764 lysosome IEP Predicted GO
CC GO:0005767 secondary lysosome IEP Predicted GO
CC GO:0005773 vacuole IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005850 eukaryotic translation initiation factor 2 complex IEP Predicted GO
BP GO:0006002 fructose 6-phosphate metabolic process IEP Predicted GO
BP GO:0006109 regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006351 transcription, DNA-templated IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006397 mRNA processing IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006541 glutamine metabolic process IEP Predicted GO
BP GO:0006542 glutamine biosynthetic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006857 oligopeptide transport IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008187 poly-pyrimidine tract binding IEP Predicted GO
BP GO:0008380 RNA splicing IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
MF GO:0008452 RNA ligase activity IEP Predicted GO
BP GO:0008593 regulation of Notch signaling pathway IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009084 glutamine family amino acid biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Predicted GO
MF GO:0009678 hydrogen-translocating pyrophosphatase activity IEP Predicted GO
BP GO:0009966 regulation of signal transduction IEP Predicted GO
BP GO:0009967 positive regulation of signal transduction IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010322 regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010323 negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010563 negative regulation of phosphorus metabolic process IEP Predicted GO
BP GO:0010565 regulation of cellular ketone metabolic process IEP Predicted GO
BP GO:0010646 regulation of cell communication IEP Predicted GO
BP GO:0010647 positive regulation of cell communication IEP Predicted GO
BP GO:0010675 regulation of cellular carbohydrate metabolic process IEP Predicted GO
BP GO:0010677 negative regulation of cellular carbohydrate metabolic process IEP Predicted GO
MF GO:0015091 ferric iron transmembrane transporter activity IEP Predicted GO
MF GO:0015093 ferrous iron transmembrane transporter activity IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016071 mRNA metabolic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016211 ammonia ligase activity IEP Predicted GO
CC GO:0016281 eukaryotic translation initiation factor 4F complex IEP Predicted GO
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Predicted GO
MF GO:0016880 acid-ammonia (or amide) ligase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
MF GO:0019203 carbohydrate phosphatase activity IEP Predicted GO
BP GO:0019216 regulation of lipid metabolic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019747 regulation of isoprenoid metabolic process IEP Predicted GO
CC GO:0020020 food vacuole IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
BP GO:0023051 regulation of signaling IEP Predicted GO
BP GO:0023056 positive regulation of signaling IEP Predicted GO
CC GO:0030139 endocytic vesicle IEP Predicted GO
MF GO:0030145 manganese ion binding IEP Predicted GO
MF GO:0030621 U4 snRNA binding IEP Predicted GO
CC GO:0030684 preribosome IEP Predicted GO
CC GO:0030687 preribosome, large subunit precursor IEP Predicted GO
CC GO:0031410 cytoplasmic vesicle IEP Predicted GO
CC GO:0031428 box C/D snoRNP complex IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
CC GO:0032010 phagolysosome IEP Predicted GO
CC GO:0032040 small-subunit processome IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
MF GO:0033677 DNA/RNA helicase activity IEP Predicted GO
MF GO:0033679 3'-5' DNA/RNA helicase activity IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
CC GO:0034457 Mpp10 complex IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
MF GO:0034511 U3 snoRNA binding IEP Predicted GO
BP GO:0034635 glutathione transport IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
BP GO:0042273 ribosomal large subunit biogenesis IEP Predicted GO
BP GO:0042939 tripeptide transport IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043484 regulation of RNA splicing IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
CC GO:0044164 host cell cytosol IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044452 nucleolar part IEP Predicted GO
CC GO:0045335 phagocytic vesicle IEP Predicted GO
BP GO:0045747 positive regulation of Notch signaling pathway IEP Predicted GO
BP GO:0045827 negative regulation of isoprenoid metabolic process IEP Predicted GO
BP GO:0045833 negative regulation of lipid metabolic process IEP Predicted GO
BP GO:0045912 negative regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0045936 negative regulation of phosphate metabolic process IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046890 regulation of lipid biosynthetic process IEP Predicted GO
MF GO:0047334 diphosphate-fructose-6-phosphate 1-phosphotransferase activity IEP Predicted GO
BP GO:0048584 positive regulation of response to stimulus IEP Predicted GO
MF GO:0050308 sugar-phosphatase activity IEP Predicted GO
BP GO:0051055 negative regulation of lipid biosynthetic process IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051181 cofactor transport IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0062012 regulation of small molecule metabolic process IEP Predicted GO
BP GO:0062014 negative regulation of small molecule metabolic process IEP Predicted GO
MF GO:0070001 aspartic-type peptidase activity IEP Predicted GO
BP GO:0071071 regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0071072 negative regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0072337 modified amino acid transport IEP Predicted GO
BP GO:0072348 sulfur compound transport IEP Predicted GO
MF GO:0072509 divalent inorganic cation transmembrane transporter activity IEP Predicted GO
MF GO:0072510 trivalent inorganic cation transmembrane transporter activity IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
BP GO:0097659 nucleic acid-templated transcription IEP Predicted GO
CC GO:0097708 intracellular vesicle IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
CC GO:1903561 extracellular vesicle IEP Predicted GO
BP GO:1903725 regulation of phospholipid metabolic process IEP Predicted GO
BP GO:1903726 negative regulation of phospholipid metabolic process IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR000086 NUDIX_hydrolase_dom 31 127
PlasmoDB 813022
PlasmoDB MAL5P1.207
PlasmoDB PFE1035c