PF3D7_0528500 (CPalpha)

Aliases : CPalpha

Description : SSF90096: F-actin-capping protein subunit alpha/beta. Pfam domain(s): PF01267: F-actin capping protein alpha subunit.

Gene families : OG_01_0003009 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0003009_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0528500
Cluster	P. falciparum: Cluster_42

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1243100	CPalpha	SSF90096: F-actin-capping protein subunit alpha/beta....	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003779	actin binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0008064	regulation of actin polymerization or depolymerization	None	Extended
MF	GO:0008092	cytoskeletal protein binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
CC	GO:0008290	F-actin capping protein complex	IEA	Interproscan predictions
CC	GO:0008290	F-actin capping protein complex	IEA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010639	negative regulation of organelle organization	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0030832	regulation of actin filament length	None	Extended
BP	GO:0030833	regulation of actin filament polymerization	None	Extended
BP	GO:0030834	regulation of actin filament depolymerization	None	Extended
BP	GO:0030835	negative regulation of actin filament depolymerization	None	Extended
BP	GO:0030837	negative regulation of actin filament polymerization	None	Extended
BP	GO:0031333	negative regulation of protein complex assembly	None	Extended
BP	GO:0032271	regulation of protein polymerization	None	Extended
BP	GO:0032272	negative regulation of protein polymerization	None	Extended
BP	GO:0032535	regulation of cellular component size	None	Extended
BP	GO:0032956	regulation of actin cytoskeleton organization	None	Extended
BP	GO:0032970	regulation of actin filament-based process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033043	regulation of organelle organization	None	Extended
BP	GO:0043242	negative regulation of protein complex disassembly	None	Extended
BP	GO:0043244	regulation of protein complex disassembly	None	Extended
BP	GO:0043254	regulation of protein complex assembly	None	Extended
BP	GO:0044087	regulation of cellular component biogenesis	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044430	cytoskeletal part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0044877	protein-containing complex binding	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
MF	GO:0051015	actin filament binding	ISO	PlasmoDB
BP	GO:0051016	barbed-end actin filament capping	IEA	Interproscan predictions
BP	GO:0051016	barbed-end actin filament capping	IEA	PlasmoDB
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051129	negative regulation of cellular component organization	None	Extended
BP	GO:0051493	regulation of cytoskeleton organization	None	Extended
BP	GO:0051494	negative regulation of cytoskeleton organization	None	Extended
BP	GO:0051693	actin filament capping	None	Extended
BP	GO:0051693	actin filament capping	ISO	PlasmoDB
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090066	regulation of anatomical structure size	None	Extended
BP	GO:0110053	regulation of actin filament organization	None	Extended
BP	GO:1901879	regulation of protein depolymerization	None	Extended
BP	GO:1901880	negative regulation of protein depolymerization	None	Extended
BP	GO:1902903	regulation of supramolecular fiber organization	None	Extended
BP	GO:1902904	negative regulation of supramolecular fiber organization	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0004721	phosphoprotein phosphatase activity	IEP	Predicted GO
MF	GO:0004725	protein tyrosine phosphatase activity	IEP	Predicted GO
MF	GO:0004798	thymidylate kinase activity	IEP	Predicted GO
MF	GO:0005200	structural constituent of cytoskeleton	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005869	dynactin complex	IEP	Predicted GO
CC	GO:0005875	microtubule associated complex	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006227	dUDP biosynthetic process	IEP	Predicted GO
BP	GO:0006233	dTDP biosynthetic process	IEP	Predicted GO
BP	GO:0006235	dTTP biosynthetic process	IEP	Predicted GO
BP	GO:0006470	protein dephosphorylation	IEP	Predicted GO
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	IEP	Predicted GO
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009133	nucleoside diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009138	pyrimidine nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009139	pyrimidine nucleoside diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009186	deoxyribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009196	pyrimidine deoxyribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009197	pyrimidine deoxyribonucleoside diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009212	pyrimidine deoxyribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0016311	dephosphorylation	IEP	Predicted GO
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Predicted GO
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
BP	GO:0046072	dTDP metabolic process	IEP	Predicted GO
BP	GO:0046075	dTTP metabolic process	IEP	Predicted GO
BP	GO:0046077	dUDP metabolic process	IEP	Predicted GO
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Predicted GO
MF	GO:0050145	nucleoside monophosphate kinase activity	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002189	CapZ_alpha	13	294

External Links

PlasmoDB	813098
PlasmoDB	MAL5P1.282
PlasmoDB	PFE1420w

PF3D7_0528500 (CPalpha)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation