PF3D7_0622800

Description : SSF47323: "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding", SSF50677: "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain", SSF52374: No description available. Pfam domain(s): PF08264: Anticodon-binding domain of tRNA, PF00133: "tRNA synthetases class I (I, L, M and V)".

Gene families : OG_01_0001441 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001441_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0622800
Cluster	P. falciparum: Cluster_4

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan predictions
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan predictions
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0004823	leucine-tRNA ligase activity	ISS	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	ISS	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan predictions
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	PlasmoDB
BP	GO:0006429	leucyl-tRNA aminoacylation	ISS	PlasmoDB
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000027	ribosomal large subunit assembly	IEP	Predicted GO
MF	GO:0000049	tRNA binding	IEP	Predicted GO
BP	GO:0000245	spliceosomal complex assembly	IEP	Predicted GO
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003688	DNA replication origin binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003872	6-phosphofructokinase activity	IEP	Predicted GO
MF	GO:0004197	cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Predicted GO
MF	GO:0004482	mRNA (guanine-N7-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004818	glutamate-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004821	histidine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005665	RNA polymerase II, core complex	IEP	Predicted GO
CC	GO:0005686	U2 snRNP	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005773	vacuole	IEP	Predicted GO
CC	GO:0005832	chaperonin-containing T-complex	IEP	Predicted GO
CC	GO:0005851	eukaryotic translation initiation factor 2B complex	IEP	Predicted GO
BP	GO:0006002	fructose 6-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006370	7-methylguanosine mRNA capping	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006424	glutamyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006427	histidyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006541	glutamine metabolic process	IEP	Predicted GO
BP	GO:0006542	glutamine biosynthetic process	IEP	Predicted GO
MF	GO:0008174	mRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008443	phosphofructokinase activity	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009064	glutamine family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009452	7-methylguanosine RNA capping	IEP	Predicted GO
BP	GO:0016053	organic acid biosynthetic process	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
MF	GO:0016211	ammonia ligase activity	IEP	Predicted GO
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Predicted GO
MF	GO:0017069	snRNA binding	IEP	Predicted GO
MF	GO:0017070	U6 snRNA binding	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
CC	GO:0030430	host cell cytoplasm	IEP	Predicted GO
MF	GO:0030623	U5 snRNA binding	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0036260	RNA capping	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
CC	GO:0043190	ATP-binding cassette (ABC) transporter complex	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Predicted GO
MF	GO:0047334	diphosphate-fructose-6-phosphate 1-phosphotransferase activity	IEP	Predicted GO
BP	GO:0051052	regulation of DNA metabolic process	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Predicted GO
CC	GO:0098533	ATPase dependent transmembrane transport complex	IEP	Predicted GO
CC	GO:0101031	chaperone complex	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Predicted GO
CC	GO:1902495	transmembrane transporter complex	IEP	Predicted GO
CC	GO:1904949	ATPase complex	IEP	Predicted GO
CC	GO:1990351	transporter complex	IEP	Predicted GO
MF	GO:1990837	sequence-specific double-stranded DNA binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	1064	1186
IPR002300	aa-tRNA-synth_Ia	524	808
IPR002300	aa-tRNA-synth_Ia	14	114

External Links

PlasmoDB	2270.t00116
PlasmoDB	3885858
PlasmoDB	MAL6P1.201
PlasmoDB	PFF1095w

PF3D7_0622800

Expression Profile

Co-expression Networks

Functional Annotation