PF3D7_0624600 (ISWI)

Aliases : ISWI

Description : SSF57903: "Zinc finger, FYVE/PHD-type", SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00271: Helicase conserved C-terminal domain, PF00628: PHD-finger, PF00176: SNF2 family N-terminal domain.

Gene families : OG_01_0001449 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001449_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0624600
Cluster	P. falciparum: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1123500	ISWI	SSF57903: Zinc finger, FYVE/PHD-type, SSF52540: P-loop...	0.12	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	ISS	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IDA	PlasmoDB
BP	GO:0006325	chromatin organization	None	Extended
BP	GO:0006338	chromatin remodeling	ISS	PlasmoDB
MF	GO:0008026	ATP-dependent helicase activity	ISS	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0070035	purine NTP-dependent helicase activity	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003700	DNA-binding transcription factor activity	IEP	Predicted GO
MF	GO:0004430	1-phosphatidylinositol 4-kinase activity	IEP	Predicted GO
MF	GO:0004683	calmodulin-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0004686	elongation factor-2 kinase activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005871	kinesin complex	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006644	phospholipid metabolic process	IEP	Predicted GO
BP	GO:0006650	glycerophospholipid metabolic process	IEP	Predicted GO
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0009889	regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0010468	regulation of gene expression	IEP	Predicted GO
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0016311	dephosphorylation	IEP	Predicted GO
CC	GO:0016469	proton-transporting two-sector ATPase complex	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0019222	regulation of metabolic process	IEP	Predicted GO
MF	GO:0019904	protein domain specific binding	IEP	Predicted GO
CC	GO:0030015	CCR4-NOT core complex	IEP	Predicted GO
CC	GO:0030126	COPI vesicle coat	IEP	Predicted GO
BP	GO:0030258	lipid modification	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Predicted GO
CC	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEP	Predicted GO
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
MF	GO:0035091	phosphatidylinositol binding	IEP	Predicted GO
BP	GO:0035690	cellular response to drug	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
MF	GO:0043565	sequence-specific DNA binding	IEP	Predicted GO
BP	GO:0046486	glycerolipid metabolic process	IEP	Predicted GO
BP	GO:0046488	phosphatidylinositol metabolic process	IEP	Predicted GO
BP	GO:0046839	phospholipid dephosphorylation	IEP	Predicted GO
BP	GO:0046856	phosphatidylinositol dephosphorylation	IEP	Predicted GO
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
MF	GO:0052742	phosphatidylinositol kinase activity	IEP	Predicted GO
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0070887	cellular response to chemical stimulus	IEP	Predicted GO
BP	GO:0080090	regulation of primary metabolic process	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR019787	Znf_PHD-finger	71	117
IPR001650	Helicase_C	1091	1191
IPR000330	SNF2_N	357	644

External Links

PlasmoDB	2270.t00132
PlasmoDB	3885918
PlasmoDB	MAL6P1.183
PlasmoDB	PFF1185w

PF3D7_0624600 (ISWI)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation