PF3D7_0706700 (MSH2-2)

Aliases : MSH2-2

Description : SSF48334: "DNA mismatch repair protein MutS, core domain superfamily", SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF05192: MutS domain III, PF00488: MutS domain V.

Gene families : OG_01_0000121 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000121_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0706700
Cluster	P. falciparum: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0804300	MSH2-2	SSF48334: DNA mismatch repair protein MutS, core domain...	0.01	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan predictions
BP	GO:0006298	mismatch repair	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan predictions
MF	GO:0030983	mismatched DNA binding	IEA	PlasmoDB
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity	IEP	Predicted GO
MF	GO:0051748	UTP-monosaccharide-1-phosphate uridylyltransferase activity	IEP	Predicted GO
MF	GO:0070569	uridylyltransferase activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR007696	DNA_mismatch_repair_MutS_core	169	561
IPR000432	DNA_mismatch_repair_MutS_C	620	808

External Links

PlasmoDB	9221883
PlasmoDB	MAL7P1.206
PlasmoDB	PF00_0002

PF3D7_0706700 (MSH2-2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation