PF3D7_0709500

Description : SSF50249: "Nucleic acid-binding, OB-fold". Pfam domain(s): PF08661: Replication factor A protein 3.

Gene families : OG_01_0004097 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0004097_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0709500
Cluster	P. falciparum: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1220000	No alias	SSF50249: Nucleic acid-binding, OB-fold. Pfam domain(s):...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan predictions
CC	GO:0005634	nucleus	IEA	PlasmoDB
CC	GO:0005737	cytoplasm	IEA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan predictions
BP	GO:0006260	DNA replication	IEA	PlasmoDB
BP	GO:0006281	DNA repair	IEA	Interproscan predictions
BP	GO:0006281	DNA repair	IEA	PlasmoDB
BP	GO:0006310	DNA recombination	IEA	Interproscan predictions
BP	GO:0006310	DNA recombination	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000225	N-acetylglucosaminylphosphatidylinositol deacetylase activity	IEP	Predicted GO
CC	GO:0000311	plastid large ribosomal subunit	IEP	Predicted GO
CC	GO:0000313	organellar ribosome	IEP	Predicted GO
CC	GO:0000315	organellar large ribosomal subunit	IEP	Predicted GO
CC	GO:0000775	chromosome, centromeric region	IEP	Predicted GO
CC	GO:0000776	kinetochore	IEP	Predicted GO
BP	GO:0001505	regulation of neurotransmitter levels	IEP	Predicted GO
MF	GO:0003714	transcription corepressor activity	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Predicted GO
MF	GO:0004146	dihydrofolate reductase activity	IEP	Predicted GO
MF	GO:0004311	farnesyltranstransferase activity	IEP	Predicted GO
MF	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	IEP	Predicted GO
MF	GO:0004462	lactoylglutathione lyase activity	IEP	Predicted GO
MF	GO:0004576	oligosaccharyl transferase activity	IEP	Predicted GO
MF	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004775	succinate-CoA ligase (ADP-forming) activity	IEP	Predicted GO
MF	GO:0004799	thymidylate synthase activity	IEP	Predicted GO
MF	GO:0005385	zinc ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005658	alpha DNA polymerase:primase complex	IEP	Predicted GO
CC	GO:0005672	transcription factor TFIIA complex	IEP	Predicted GO
CC	GO:0005761	mitochondrial ribosome	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005868	cytoplasmic dynein complex	IEP	Predicted GO
CC	GO:0005887	integral component of plasma membrane	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006231	dTMP biosynthetic process	IEP	Predicted GO
BP	GO:0006272	leading strand elongation	IEP	Predicted GO
BP	GO:0006337	nucleosome disassembly	IEP	Predicted GO
BP	GO:0006487	protein N-linked glycosylation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006544	glycine metabolic process	IEP	Predicted GO
BP	GO:0006545	glycine biosynthetic process	IEP	Predicted GO
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006633	fatty acid biosynthetic process	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006749	glutathione metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006829	zinc ion transport	IEP	Predicted GO
CC	GO:0008250	oligosaccharyltransferase complex	IEP	Predicted GO
MF	GO:0008495	protoheme IX farnesyltransferase activity	IEP	Predicted GO
BP	GO:0008535	respiratory chain complex IV assembly	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
MF	GO:0008897	holo-[acyl-carrier-protein] synthase activity	IEP	Predicted GO
BP	GO:0009070	serine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
BP	GO:0016053	organic acid biosynthetic process	IEP	Predicted GO
BP	GO:0016458	gene silencing	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
BP	GO:0016573	histone acetylation	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Predicted GO
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016846	carbon-sulfur lyase activity	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
CC	GO:0030121	AP-1 adaptor complex	IEP	Predicted GO
MF	GO:0030604	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	IEP	Predicted GO
CC	GO:0031262	Ndc80 complex	IEP	Predicted GO
BP	GO:0031497	chromatin assembly	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0032986	protein-DNA complex disassembly	IEP	Predicted GO
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0042133	neurotransmitter metabolic process	IEP	Predicted GO
BP	GO:0042136	neurotransmitter biosynthetic process	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0044435	plastid part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
BP	GO:0046073	dTMP metabolic process	IEP	Predicted GO
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
BP	GO:0046653	tetrahydrofolate metabolic process	IEP	Predicted GO
BP	GO:0046654	tetrahydrofolate biosynthetic process	IEP	Predicted GO
BP	GO:0048033	heme o metabolic process	IEP	Predicted GO
BP	GO:0048034	heme O biosynthetic process	IEP	Predicted GO
MF	GO:0050661	NADP binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051188	cofactor biosynthetic process	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
MF	GO:0070402	NADPH binding	IEP	Predicted GO
BP	GO:0071897	DNA biosynthetic process	IEP	Predicted GO
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Predicted GO
MF	GO:0072509	divalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013970	Rfa2	32	123

External Links

PlasmoDB	2655075
PlasmoDB	PF07_0039

PF3D7_0709500

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation