PF3D7_0717500 (CDPK4)

Aliases : CDPK4

Description : SSF47473: EF-hand domain pair, SSF56112: Protein kinase-like domain superfamily. Pfam domain(s): PF13499: EF-hand domain pair, PF00069: Protein kinase domain.

Gene families : OG_01_0000029 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000029_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0717500
Cluster	P. falciparum: Cluster_34

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0615200	CDPK4	SSF56112: Protein kinase-like domain superfamily,...	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
BP	GO:0000226	microtubule cytoskeleton organization	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003824	catalytic activity	IDA	PlasmoDB
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0004721	phosphoprotein phosphatase activity	None	Extended
MF	GO:0004722	protein serine/threonine phosphatase activity	None	Extended
MF	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	IDA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005509	calcium ion binding	IDA	PlasmoDB
MF	GO:0005509	calcium ion binding	IEA	Interproscan predictions
MF	GO:0005509	calcium ion binding	IEA	PlasmoDB
MF	GO:0005524	ATP binding	ISS	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	ISO	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	IDA	PlasmoDB
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0007010	cytoskeleton organization	None	Extended
BP	GO:0007017	microtubule-based process	None	Extended
BP	GO:0007051	spindle organization	None	Extended
BP	GO:0007052	mitotic spindle organization	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016791	phosphatase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0022607	cellular component assembly	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034622	cellular protein-containing complex assembly	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0036388	pre-replicative complex assembly	ISO	PlasmoDB
CC	GO:0042555	MCM complex	ISO	PlasmoDB
MF	GO:0042578	phosphoric ester hydrolase activity	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043933	protein-containing complex subunit organization	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0051225	spindle assembly	None	Extended
BP	GO:0065003	protein-containing complex assembly	None	Extended
BP	GO:0065004	protein-DNA complex assembly	None	Extended
BP	GO:0070925	organelle assembly	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071824	protein-DNA complex subunit organization	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:0090307	mitotic spindle assembly	ISO	PlasmoDB
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	None	Extended
BP	GO:1903047	mitotic cell cycle process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005813	centrosome	IEP	Predicted GO
CC	GO:0005815	microtubule organizing center	IEP	Predicted GO
CC	GO:0005819	spindle	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005871	kinesin complex	IEP	Predicted GO
CC	GO:0005955	calcineurin complex	IEP	Predicted GO
BP	GO:0006470	protein dephosphorylation	IEP	Predicted GO
MF	GO:0008017	microtubule binding	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0016311	dephosphorylation	IEP	Predicted GO
MF	GO:0016409	palmitoyltransferase activity	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
BP	GO:0018345	protein palmitoylation	IEP	Predicted GO
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0031399	regulation of protein modification process	IEP	Predicted GO
BP	GO:0031400	negative regulation of protein modification process	IEP	Predicted GO
BP	GO:0032269	negative regulation of cellular protein metabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0050746	regulation of lipoprotein metabolic process	IEP	Predicted GO
BP	GO:0050748	negative regulation of lipoprotein metabolic process	IEP	Predicted GO
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051248	negative regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051301	cell division	IEP	Predicted GO
BP	GO:1903059	regulation of protein lipidation	IEP	Predicted GO
BP	GO:1903060	negative regulation of protein lipidation	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002048	EF_hand_dom	462	521
IPR002048	EF_hand_dom	380	450
IPR000719	Prot_kinase_dom	70	328

External Links

PlasmoDB	2655116
PlasmoDB	PF07_0072

PF3D7_0717500 (CDPK4)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation