PF3D7_0719200 (NEK4)

Aliases : NEK4

Description : SSF56112: Protein kinase-like domain superfamily. Pfam domain(s): PF00069: Protein kinase domain.

Gene families : OG_01_0000194 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000194_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0719200
Cluster	P. falciparum: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0616700	NEK4	SSF56112: Protein kinase-like domain superfamily. Pfam...	0.09	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0004674	protein serine/threonine kinase activity	IDA	PlasmoDB
MF	GO:0004674	protein serine/threonine kinase activity	ISS	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	ISS	PlasmoDB
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0007165	signal transduction	ISS	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000150	recombinase activity	IEP	Predicted GO
BP	GO:0000270	peptidoglycan metabolic process	IEP	Predicted GO
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
BP	GO:0000902	cell morphogenesis	IEP	Predicted GO
CC	GO:0002178	palmitoyltransferase complex	IEP	Predicted GO
CC	GO:0002179	homodimeric serine palmitoyltransferase complex	IEP	Predicted GO
MF	GO:0003872	6-phosphofructokinase activity	IEP	Predicted GO
MF	GO:0003977	UDP-N-acetylglucosamine diphosphorylase activity	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004758	serine C-palmitoyltransferase activity	IEP	Predicted GO
MF	GO:0005044	scavenger receptor activity	IEP	Predicted GO
CC	GO:0005576	extracellular region	IEP	Predicted GO
CC	GO:0005868	cytoplasmic dynein complex	IEP	Predicted GO
CC	GO:0005869	dynactin complex	IEP	Predicted GO
CC	GO:0005875	microtubule associated complex	IEP	Predicted GO
CC	GO:0005892	acetylcholine-gated channel complex	IEP	Predicted GO
BP	GO:0005975	carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0006004	fucose metabolic process	IEP	Predicted GO
BP	GO:0006022	aminoglycan metabolic process	IEP	Predicted GO
BP	GO:0006023	aminoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0006024	glycosaminoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0006166	purine ribonucleoside salvage	IEP	Predicted GO
BP	GO:0006190	inosine salvage	IEP	Predicted GO
BP	GO:0006665	sphingolipid metabolic process	IEP	Predicted GO
BP	GO:0006817	phosphate ion transport	IEP	Predicted GO
BP	GO:0006820	anion transport	IEP	Predicted GO
BP	GO:0006928	movement of cell or subcellular component	IEP	Predicted GO
MF	GO:0008239	dipeptidyl-peptidase activity	IEP	Predicted GO
MF	GO:0008252	nucleotidase activity	IEP	Predicted GO
MF	GO:0008253	5'-nucleotidase activity	IEP	Predicted GO
BP	GO:0008360	regulation of cell shape	IEP	Predicted GO
MF	GO:0008443	phosphofructokinase activity	IEP	Predicted GO
MF	GO:0008446	GDP-mannose 4,6-dehydratase activity	IEP	Predicted GO
BP	GO:0008653	lipopolysaccharide metabolic process	IEP	Predicted GO
BP	GO:0009103	lipopolysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0009252	peptidoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0009653	anatomical structure morphogenesis	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
BP	GO:0015698	inorganic anion transport	IEP	Predicted GO
MF	GO:0016408	C-acyltransferase activity	IEP	Predicted GO
MF	GO:0016409	palmitoyltransferase activity	IEP	Predicted GO
MF	GO:0016454	C-palmitoyltransferase activity	IEP	Predicted GO
MF	GO:0016746	transferase activity, transferring acyl groups	IEP	Predicted GO
MF	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	IEP	Predicted GO
CC	GO:0017059	serine C-palmitoyltransferase complex	IEP	Predicted GO
MF	GO:0019134	glucosamine-1-phosphate N-acetyltransferase activity	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
BP	GO:0019236	response to pheromone	IEP	Predicted GO
BP	GO:0019673	GDP-mannose metabolic process	IEP	Predicted GO
CC	GO:0020025	subpellicular microtubule	IEP	Predicted GO
CC	GO:0020039	pellicle	IEP	Predicted GO
BP	GO:0022603	regulation of anatomical structure morphogenesis	IEP	Predicted GO
BP	GO:0022604	regulation of cell morphogenesis	IEP	Predicted GO
BP	GO:0030148	sphingolipid biosynthetic process	IEP	Predicted GO
BP	GO:0030203	glycosaminoglycan metabolic process	IEP	Predicted GO
CC	GO:0030286	dynein complex	IEP	Predicted GO
CC	GO:0031211	endoplasmic reticulum palmitoyltransferase complex	IEP	Predicted GO
BP	GO:0031297	replication fork processing	IEP	Predicted GO
BP	GO:0032989	cellular component morphogenesis	IEP	Predicted GO
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
CC	GO:0034702	ion channel complex	IEP	Predicted GO
MF	GO:0038024	cargo receptor activity	IEP	Predicted GO
BP	GO:0043101	purine-containing compound salvage	IEP	Predicted GO
BP	GO:0043174	nucleoside salvage	IEP	Predicted GO
CC	GO:0043235	receptor complex	IEP	Predicted GO
BP	GO:0044036	cell wall macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044038	cell wall macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
CC	GO:0044310	osmiophilic body	IEP	Predicted GO
CC	GO:0044312	crystalloid	IEP	Predicted GO
CC	GO:0044459	plasma membrane part	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
BP	GO:0046102	inosine metabolic process	IEP	Predicted GO
BP	GO:0046103	inosine biosynthetic process	IEP	Predicted GO
MF	GO:0050483	IMP 5'-nucleotidase activity	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
MF	GO:0070569	uridylyltransferase activity	IEP	Predicted GO
BP	GO:0070589	cellular component macromolecule biosynthetic process	IEP	Predicted GO
CC	GO:0071944	cell periphery	IEP	Predicted GO
CC	GO:0098797	plasma membrane protein complex	IEP	Predicted GO
CC	GO:0098802	plasma membrane receptor complex	IEP	Predicted GO
BP	GO:0120009	intermembrane lipid transfer	IEP	Predicted GO
MF	GO:0120013	intermembrane lipid transfer activity	IEP	Predicted GO
BP	GO:1902298	cell cycle DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:1902495	transmembrane transporter complex	IEP	Predicted GO
CC	GO:1905961	protein-cysteine S-palmitoyltransferase complex	IEP	Predicted GO
CC	GO:1990351	transporter complex	IEP	Predicted GO
BP	GO:1990426	mitotic recombination-dependent replication fork processing	IEP	Predicted GO
BP	GO:1990505	mitotic DNA replication maintenance of fidelity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000719	Prot_kinase_dom	4	257

External Links

PlasmoDB	2654953
PlasmoDB	MAL7P1.100

PF3D7_0719200 (NEK4)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation