PF3D7_0729900

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF12780: P-loop containing dynein motor region D4, PF17852: Dynein heavy chain AAA lid domain, PF18199: Dynein heavy chain C-terminal domain, PF03028: Dynein heavy chain region D6 P-loop domain, PF12781: ATP-binding dynein motor region, PF12775: P-loop containing dynein motor region, PF08393: "Dynein heavy chain, N-terminal region 2", PF12777: Microtubule-binding stalk of dynein motor, PF08385: "Dynein heavy chain, N-terminal region 1", PF17857: AAA+ lid domain, PF18198: Dynein heavy chain AAA lid domain, PF12774: Hydrolytic ATP binding site of dynein motor region.

Gene families : OG_01_0000020 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000020_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0729900
Cluster	P. falciparum: Cluster_33

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003774	motor activity	None	Extended
MF	GO:0003777	microtubule motor activity	ISS	PlasmoDB
MF	GO:0003777	microtubule motor activity	IEA	Interproscan predictions
MF	GO:0003777	microtubule motor activity	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005875	microtubule associated complex	None	Extended
BP	GO:0006928	movement of cell or subcellular component	None	Extended
BP	GO:0007017	microtubule-based process	None	Extended
BP	GO:0007018	microtubule-based movement	ISS	PlasmoDB
BP	GO:0007018	microtubule-based movement	IEA	Interproscan predictions
BP	GO:0007018	microtubule-based movement	IEA	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	PlasmoDB
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
CC	GO:0030286	dynein complex	IEA	Interproscan predictions
CC	GO:0030286	dynein complex	IEA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044430	cytoskeletal part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1902494	catalytic complex	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0005886	plasma membrane	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0007165	signal transduction	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009187	cyclic nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEP	Predicted GO
MF	GO:0016829	lyase activity	IEP	Predicted GO
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0035556	intracellular signal transduction	IEP	Predicted GO
BP	GO:0040011	locomotion	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0048870	cell motility	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0071976	cell gliding	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR024317	Dynein_heavy_chain_D4_dom	3106	3384
IPR013602	Dynein_heavy_dom-2	1406	1804
IPR004273	Dynein_heavy_D6_P-loop	4323	4438
IPR024743	Dynein_HC_stalk	3399	3733
IPR035706	AAA_9	3762	3978
IPR035699	AAA_6	2228	2326
IPR035699	AAA_6	1958	2196
IPR013594	Dynein_heavy_dom-1	284	854

External Links

PlasmoDB	2654986
PlasmoDB	MAL7P1.162

PF3D7_0729900

Expression Profile

Co-expression Networks

Functional Annotation