PF3D7_0809700 (RUVB1)

Aliases : RUVB1

Description : SSF50249: "Nucleic acid-binding, OB-fold", SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF17856: TIP49 AAA-lid domain, PF06068: TIP49 P-loop domain.

Gene families : OG_01_0000104 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000104_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0809700
Cluster	P. falciparum: Cluster_18

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003678	DNA helicase activity	IDA	PlasmoDB
MF	GO:0003678	DNA helicase activity	IEA	Interproscan predictions
MF	GO:0003678	DNA helicase activity	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004003	ATP-dependent DNA helicase activity	None	Extended
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
MF	GO:0008026	ATP-dependent helicase activity	None	Extended
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IDA	PlasmoDB
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043139	5'-3' DNA helicase activity	None	Extended
MF	GO:0043141	ATP-dependent 5'-3' DNA helicase activity	IDA	PlasmoDB
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0070035	purine NTP-dependent helicase activity	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000775	chromosome, centromeric region	IEP	Predicted GO
BP	GO:0001505	regulation of neurotransmitter levels	IEP	Predicted GO
BP	GO:0003352	regulation of cilium movement	IEP	Predicted GO
MF	GO:0004047	aminomethyltransferase activity	IEP	Predicted GO
MF	GO:0004112	cyclic-nucleotide phosphodiesterase activity	IEP	Predicted GO
MF	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	IEP	Predicted GO
MF	GO:0004523	RNA-DNA hybrid ribonuclease activity	IEP	Predicted GO
MF	GO:0004721	phosphoprotein phosphatase activity	IEP	Predicted GO
MF	GO:0004788	thiamine diphosphokinase activity	IEP	Predicted GO
MF	GO:0005371	tricarboxylate secondary active transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
CC	GO:0005669	transcription factor TFIID complex	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005762	mitochondrial large ribosomal subunit	IEP	Predicted GO
CC	GO:0005802	trans-Golgi network	IEP	Predicted GO
CC	GO:0005885	Arp2/3 protein complex	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006366	transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006470	protein dephosphorylation	IEP	Predicted GO
BP	GO:0006544	glycine metabolic process	IEP	Predicted GO
BP	GO:0006546	glycine catabolic process	IEP	Predicted GO
BP	GO:0006772	thiamine metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006842	tricarboxylic acid transport	IEP	Predicted GO
BP	GO:0006843	mitochondrial citrate transmembrane transport	IEP	Predicted GO
BP	GO:0006855	drug transmembrane transport	IEP	Predicted GO
BP	GO:0007015	actin filament organization	IEP	Predicted GO
BP	GO:0007021	tubulin complex assembly	IEP	Predicted GO
BP	GO:0007023	post-chaperonin tubulin folding pathway	IEP	Predicted GO
BP	GO:0007165	signal transduction	IEP	Predicted GO
BP	GO:0008064	regulation of actin polymerization or depolymerization	IEP	Predicted GO
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
BP	GO:0009063	cellular amino acid catabolic process	IEP	Predicted GO
BP	GO:0009069	serine family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009071	serine family amino acid catabolic process	IEP	Predicted GO
BP	GO:0009187	cyclic nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009229	thiamine diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009742	brassinosteroid mediated signaling pathway	IEP	Predicted GO
BP	GO:0009755	hormone-mediated signaling pathway	IEP	Predicted GO
BP	GO:0010638	positive regulation of organelle organization	IEP	Predicted GO
MF	GO:0015142	tricarboxylic acid transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015746	citrate transport	IEP	Predicted GO
BP	GO:0016054	organic acid catabolic process	IEP	Predicted GO
BP	GO:0016311	dephosphorylation	IEP	Predicted GO
MF	GO:0016778	diphosphotransferase activity	IEP	Predicted GO
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
MF	GO:0030551	cyclic nucleotide binding	IEP	Predicted GO
MF	GO:0030552	cAMP binding	IEP	Predicted GO
BP	GO:0030832	regulation of actin filament length	IEP	Predicted GO
BP	GO:0030833	regulation of actin filament polymerization	IEP	Predicted GO
BP	GO:0030838	positive regulation of actin filament polymerization	IEP	Predicted GO
MF	GO:0030975	thiamine binding	IEP	Predicted GO
CC	GO:0031262	Ndc80 complex	IEP	Predicted GO
BP	GO:0031334	positive regulation of protein complex assembly	IEP	Predicted GO
CC	GO:0031984	organelle subcompartment	IEP	Predicted GO
BP	GO:0032271	regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032273	positive regulation of protein polymerization	IEP	Predicted GO
CC	GO:0032299	ribonuclease H2 complex	IEP	Predicted GO
BP	GO:0032535	regulation of cellular component size	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
BP	GO:0032886	regulation of microtubule-based process	IEP	Predicted GO
BP	GO:0032956	regulation of actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0032970	regulation of actin filament-based process	IEP	Predicted GO
MF	GO:0035650	AP-1 adaptor complex binding	IEP	Predicted GO
BP	GO:0035674	tricarboxylic acid transmembrane transport	IEP	Predicted GO
BP	GO:0042133	neurotransmitter metabolic process	IEP	Predicted GO
BP	GO:0042135	neurotransmitter catabolic process	IEP	Predicted GO
BP	GO:0042357	thiamine diphosphate metabolic process	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
BP	GO:0042723	thiamine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042737	drug catabolic process	IEP	Predicted GO
BP	GO:0042891	antibiotic transport	IEP	Predicted GO
BP	GO:0043254	regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0043401	steroid hormone mediated signaling pathway	IEP	Predicted GO
BP	GO:0044087	regulation of cellular component biogenesis	IEP	Predicted GO
BP	GO:0044089	positive regulation of cellular component biogenesis	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0044282	small molecule catabolic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044451	nucleoplasm part	IEP	Predicted GO
CC	GO:0044798	nuclear transcription factor complex	IEP	Predicted GO
BP	GO:0045010	actin nucleation	IEP	Predicted GO
BP	GO:0046395	carboxylic acid catabolic process	IEP	Predicted GO
MF	GO:0048487	beta-tubulin binding	IEP	Predicted GO
BP	GO:0051130	positive regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051270	regulation of cellular component movement	IEP	Predicted GO
BP	GO:0051493	regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0051495	positive regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0060632	regulation of microtubule-based movement	IEP	Predicted GO
BP	GO:0090066	regulation of anatomical structure size	IEP	Predicted GO
BP	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	IEP	Predicted GO
CC	GO:0090575	RNA polymerase II transcription factor complex	IEP	Predicted GO
BP	GO:0097435	supramolecular fiber organization	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:0098656	anion transmembrane transport	IEP	Predicted GO
CC	GO:0098791	Golgi subcompartment	IEP	Predicted GO
BP	GO:0110053	regulation of actin filament organization	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Predicted GO
BP	GO:1902903	regulation of supramolecular fiber organization	IEP	Predicted GO
BP	GO:1902905	positive regulation of supramolecular fiber organization	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO
BP	GO:1903825	organic acid transmembrane transport	IEP	Predicted GO
BP	GO:1905039	carboxylic acid transmembrane transport	IEP	Predicted GO
BP	GO:1990546	mitochondrial tricarboxylic acid transmembrane transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR010339	TIP49_P-loop	12	433

External Links

PlasmoDB	2655299
PlasmoDB	PF08_0100

PF3D7_0809700 (RUVB1)

Expression Profile

Co-expression Networks

Functional Annotation