PF3D7_0812600

Description : SSF54495: Ubiquitin-conjugating enzyme/RWD-like. Pfam domain(s): PF00179: Ubiquitin-conjugating enzyme.

Gene families : OG_01_0000099 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000099_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0812600
Cluster	P. falciparum: Cluster_46

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0806000	No alias	SSF54495: Ubiquitin-conjugating enzyme/RWD-like. Pfam...	0.03	Orthofinderv1.1.8
PBANKA_1424900	No alias	SSF54495: Ubiquitin-conjugating enzyme/RWD-like. Pfam...	0.05	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004842	ubiquitin-protein transferase activity	ISS	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019787	ubiquitin-like protein transferase activity	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000150	recombinase activity	IEP	Predicted GO
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
CC	GO:0000932	P-body	IEP	Predicted GO
BP	GO:0001817	regulation of cytokine production	IEP	Predicted GO
BP	GO:0001819	positive regulation of cytokine production	IEP	Predicted GO
BP	GO:0002684	positive regulation of immune system process	IEP	Predicted GO
BP	GO:0002697	regulation of immune effector process	IEP	Predicted GO
BP	GO:0002699	positive regulation of immune effector process	IEP	Predicted GO
BP	GO:0002700	regulation of production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002718	regulation of cytokine production involved in immune response	IEP	Predicted GO
BP	GO:0002720	positive regulation of cytokine production involved in immune response	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003998	acylphosphatase activity	IEP	Predicted GO
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Predicted GO
MF	GO:0004139	deoxyribose-phosphate aldolase activity	IEP	Predicted GO
MF	GO:0004392	heme oxygenase (decyclizing) activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0004751	ribose-5-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004776	succinate-CoA ligase (GDP-forming) activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005200	structural constituent of cytoskeleton	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005680	anaphase-promoting complex	IEP	Predicted GO
CC	GO:0005682	U5 snRNP	IEP	Predicted GO
CC	GO:0005685	U1 snRNP	IEP	Predicted GO
CC	GO:0005732	small nucleolar ribonucleoprotein complex	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005740	mitochondrial envelope	IEP	Predicted GO
CC	GO:0005742	mitochondrial outer membrane translocase complex	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005869	dynactin complex	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006099	tricarboxylic acid cycle	IEP	Predicted GO
BP	GO:0006101	citrate metabolic process	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006108	malate metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006359	regulation of transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006733	oxidoreduction coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006754	ATP biosynthetic process	IEP	Predicted GO
BP	GO:0006787	porphyrin-containing compound catabolic process	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
MF	GO:0008301	DNA binding, bending	IEP	Predicted GO
BP	GO:0008614	pyridoxine metabolic process	IEP	Predicted GO
BP	GO:0008615	pyridoxine biosynthetic process	IEP	Predicted GO
BP	GO:0009052	pentose-phosphate shunt, non-oxidative branch	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009166	nucleotide catabolic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009264	deoxyribonucleotide catabolic process	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
MF	GO:0016149	translation release factor activity, codon specific	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016615	malate dehydrogenase activity	IEP	Predicted GO
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Predicted GO
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016832	aldehyde-lyase activity	IEP	Predicted GO
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Predicted GO
BP	GO:0016999	antibiotic metabolic process	IEP	Predicted GO
MF	GO:0017069	snRNA binding	IEP	Predicted GO
MF	GO:0017070	U6 snRNA binding	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019430	removal of superoxide radicals	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
BP	GO:0019439	aromatic compound catabolic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
MF	GO:0030060	L-malate dehydrogenase activity	IEP	Predicted GO
CC	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0030532	small nuclear ribonucleoprotein complex	IEP	Predicted GO
BP	GO:0031297	replication fork processing	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0031967	organelle envelope	IEP	Predicted GO
CC	GO:0031975	envelope	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033015	tetrapyrrole catabolic process	IEP	Predicted GO
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034655	nucleobase-containing compound catabolic process	IEP	Predicted GO
BP	GO:0042167	heme catabolic process	IEP	Predicted GO
CC	GO:0042709	succinate-CoA ligase complex	IEP	Predicted GO
BP	GO:0042816	vitamin B6 metabolic process	IEP	Predicted GO
BP	GO:0042819	vitamin B6 biosynthetic process	IEP	Predicted GO
CC	GO:0043186	P granule	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044270	cellular nitrogen compound catabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045244	succinate-CoA ligase complex (GDP-forming)	IEP	Predicted GO
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
BP	GO:0046149	pigment catabolic process	IEP	Predicted GO
BP	GO:0046434	organophosphate catabolic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
CC	GO:0046540	U4/U6 x U5 tri-snRNP complex	IEP	Predicted GO
BP	GO:0046700	heterocycle catabolic process	IEP	Predicted GO
BP	GO:0048584	positive regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050778	positive regulation of immune response	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051187	cofactor catabolic process	IEP	Predicted GO
BP	GO:0051239	regulation of multicellular organismal process	IEP	Predicted GO
BP	GO:0051240	positive regulation of multicellular organismal process	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
CC	GO:0070971	endoplasmic reticulum exit site	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
CC	GO:0097525	spliceosomal snRNP complex	IEP	Predicted GO
CC	GO:0097526	spliceosomal tri-snRNP complex	IEP	Predicted GO
BP	GO:0098754	detoxification	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
CC	GO:0098799	outer mitochondrial membrane protein complex	IEP	Predicted GO
BP	GO:0098869	cellular oxidant detoxification	IEP	Predicted GO
CC	GO:0120114	Sm-like protein family complex	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901292	nucleoside phosphate catabolic process	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901361	organic cyclic compound catabolic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1902298	cell cycle DNA replication maintenance of fidelity	IEP	Predicted GO
BP	GO:1990426	mitotic recombination-dependent replication fork processing	IEP	Predicted GO
BP	GO:1990505	mitotic DNA replication maintenance of fidelity	IEP	Predicted GO
BP	GO:1990748	cellular detoxification	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000608	UBQ-conjugat_E2	8	144

External Links

PlasmoDB	2655284
PlasmoDB	PF08_0085

PF3D7_0812600

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation