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  5. PF3D7_0923800

PF3D7_0923800 (TRXR)


Aliases : TRXR

Description : SSF55424: "FAD/NAD-linked reductase, dimerisation domain superfamily", SSF51905: FAD/NAD(P)-binding domain superfamily. Pfam domain(s): PF07992: Pyridine nucleotide-disulphide oxidoreductase, PF02852: "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain".


Gene families : OG_01_0001020 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001020_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0923800
Cluster P. falciparum: Cluster_10

Target Alias Description ECC score Gene Family Method Actions
PBANKA_0824700 TRXR SSF51905: FAD/NAD(P)-binding domain superfamily,... 0.03 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0004791 thioredoxin-disulfide reductase activity IEA PlasmoDB
CC GO:0005737 cytoplasm IDA PlasmoDB
CC GO:0005739 mitochondrion IDA PlasmoDB
MF GO:0009055 electron transfer activity IEA PlasmoDB
MF GO:0016491 oxidoreductase activity IEA Interproscan predictions
MF GO:0016491 oxidoreductase activity IEA PlasmoDB
BP GO:0045454 cell redox homeostasis IEA Interproscan predictions
BP GO:0045454 cell redox homeostasis IEA PlasmoDB
MF GO:0050660 flavin adenine dinucleotide binding IEA PlasmoDB
BP GO:0055114 oxidation-reduction process IEA Interproscan predictions
BP GO:0055114 oxidation-reduction process IEA PlasmoDB
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Type GO Term Name Evidence Source
MF GO:0000234 phosphoethanolamine N-methyltransferase activity IEP Predicted GO
CC GO:0000315 organellar large ribosomal subunit IEP Predicted GO
CC GO:0000502 proteasome complex IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0003689 DNA clamp loader activity IEP Predicted GO
MF GO:0003998 acylphosphatase activity IEP Predicted GO
MF GO:0004013 adenosylhomocysteinase activity IEP Predicted GO
MF GO:0004170 dUTP diphosphatase activity IEP Predicted GO
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004353 glutamate dehydrogenase [NAD(P)+] activity IEP Predicted GO
MF GO:0004354 glutamate dehydrogenase (NADP+) activity IEP Predicted GO
MF GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity IEP Predicted GO
MF GO:0004372 glycine hydroxymethyltransferase activity IEP Predicted GO
MF GO:0004392 heme oxygenase (decyclizing) activity IEP Predicted GO
MF GO:0004417 hydroxyethylthiazole kinase activity IEP Predicted GO
MF GO:0004448 isocitrate dehydrogenase activity IEP Predicted GO
MF GO:0004450 isocitrate dehydrogenase (NADP+) activity IEP Predicted GO
MF GO:0004550 nucleoside diphosphate kinase activity IEP Predicted GO
MF GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004784 superoxide dismutase activity IEP Predicted GO
MF GO:0004825 methionine-tRNA ligase activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005310 dicarboxylic acid transmembrane transporter activity IEP Predicted GO
MF GO:0005342 organic acid transmembrane transporter activity IEP Predicted GO
MF GO:0005385 zinc ion transmembrane transporter activity IEP Predicted GO
MF GO:0005483 soluble NSF attachment protein activity IEP Predicted GO
CC GO:0005663 DNA replication factor C complex IEP Predicted GO
CC GO:0005740 mitochondrial envelope IEP Predicted GO
CC GO:0005743 mitochondrial inner membrane IEP Predicted GO
CC GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006099 tricarboxylic acid cycle IEP Predicted GO
BP GO:0006101 citrate metabolic process IEP Predicted GO
BP GO:0006102 isocitrate metabolic process IEP Predicted GO
BP GO:0006103 2-oxoglutarate metabolic process IEP Predicted GO
BP GO:0006108 malate metabolic process IEP Predicted GO
BP GO:0006116 NADH oxidation IEP Predicted GO
BP GO:0006127 glycerophosphate shuttle IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006183 GTP biosynthetic process IEP Predicted GO
BP GO:0006228 UTP biosynthetic process IEP Predicted GO
BP GO:0006241 CTP biosynthetic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006260 DNA replication IEP Predicted GO
BP GO:0006270 DNA replication initiation IEP Predicted GO
BP GO:0006271 DNA strand elongation involved in DNA replication IEP Predicted GO
BP GO:0006272 leading strand elongation IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0006431 methionyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0006537 glutamate biosynthetic process IEP Predicted GO
BP GO:0006545 glycine biosynthetic process IEP Predicted GO
BP GO:0006563 L-serine metabolic process IEP Predicted GO
BP GO:0006627 protein processing involved in protein targeting to mitochondrion IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006734 NADH metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006754 ATP biosynthetic process IEP Predicted GO
BP GO:0006778 porphyrin-containing compound metabolic process IEP Predicted GO
BP GO:0006784 heme a biosynthetic process IEP Predicted GO
BP GO:0006787 porphyrin-containing compound catabolic process IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006801 superoxide metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006811 ion transport IEP Predicted GO
BP GO:0006812 cation transport IEP Predicted GO
BP GO:0006829 zinc ion transport IEP Predicted GO
BP GO:0006835 dicarboxylic acid transport IEP Predicted GO
MF GO:0008094 DNA-dependent ATPase activity IEP Predicted GO
MF GO:0008121 ubiquinol-cytochrome-c reductase activity IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008324 cation transmembrane transporter activity IEP Predicted GO
MF GO:0008509 anion transmembrane transporter activity IEP Predicted GO
MF GO:0008514 organic anion transmembrane transporter activity IEP Predicted GO
BP GO:0008535 respiratory chain complex IV assembly IEP Predicted GO
CC GO:0008540 proteasome regulatory particle, base subcomplex IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009057 macromolecule catabolic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009070 serine family amino acid biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009218 pyrimidine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009220 pyrimidine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009228 thiamine biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
CC GO:0009331 glycerol-3-phosphate dehydrogenase complex IEP Predicted GO
BP GO:0015074 DNA integration IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015077 monovalent inorganic cation transmembrane transporter activity IEP Predicted GO
MF GO:0015078 proton transmembrane transporter activity IEP Predicted GO
MF GO:0015140 malate transmembrane transporter activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
MF GO:0015367 oxoglutarate:malate antiporter activity IEP Predicted GO
MF GO:0015556 C4-dicarboxylate transmembrane transporter activity IEP Predicted GO
BP GO:0015711 organic anion transport IEP Predicted GO
BP GO:0015740 C4-dicarboxylate transport IEP Predicted GO
BP GO:0015742 alpha-ketoglutarate transport IEP Predicted GO
BP GO:0015743 malate transport IEP Predicted GO
BP GO:0015849 organic acid transport IEP Predicted GO
BP GO:0015985 energy coupled proton transport, down electrochemical gradient IEP Predicted GO
BP GO:0015986 ATP synthesis coupled proton transport IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
CC GO:0016272 prefoldin complex IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
BP GO:0016485 protein processing IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors IEP Predicted GO
MF GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor IEP Predicted GO
MF GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor IEP Predicted GO
MF GO:0016742 hydroxymethyl-, formyl- and related transferase activity IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016801 hydrolase activity, acting on ether bonds IEP Predicted GO
MF GO:0016802 trialkylsulfonium hydrolase activity IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor IEP Predicted GO
BP GO:0016999 antibiotic metabolic process IEP Predicted GO
BP GO:0017004 cytochrome complex assembly IEP Predicted GO
BP GO:0017062 respiratory chain complex III assembly IEP Predicted GO
CC GO:0017087 mitochondrial processing peptidase complex IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
CC GO:0019005 SCF ubiquitin ligase complex IEP Predicted GO
BP GO:0019264 glycine biosynthetic process from serine IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019674 NAD metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
CC GO:0019774 proteasome core complex, beta-subunit complex IEP Predicted GO
MF GO:0019842 vitamin binding IEP Predicted GO
CC GO:0019866 organelle inner membrane IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
BP GO:0022616 DNA strand elongation IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0022890 inorganic cation transmembrane transporter activity IEP Predicted GO
MF GO:0030337 DNA polymerase processivity factor activity IEP Predicted GO
MF GO:0030976 thiamine pyrophosphate binding IEP Predicted GO
CC GO:0031090 organelle membrane IEP Predicted GO
CC GO:0031966 mitochondrial membrane IEP Predicted GO
CC GO:0031974 membrane-enclosed lumen IEP Predicted GO
MF GO:0032552 deoxyribonucleotide binding IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033013 tetrapyrrole metabolic process IEP Predicted GO
BP GO:0033015 tetrapyrrole catabolic process IEP Predicted GO
BP GO:0033108 mitochondrial respiratory chain complex assembly IEP Predicted GO
MF GO:0033170 protein-DNA loading ATPase activity IEP Predicted GO
BP GO:0034308 primary alcohol metabolic process IEP Predicted GO
BP GO:0034551 mitochondrial respiratory chain complex III assembly IEP Predicted GO
BP GO:0034622 cellular protein-containing complex assembly IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034982 mitochondrial protein processing IEP Predicted GO
BP GO:0035999 tetrahydrofolate interconversion IEP Predicted GO
BP GO:0042136 neurotransmitter biosynthetic process IEP Predicted GO
BP GO:0042167 heme catabolic process IEP Predicted GO
BP GO:0042168 heme metabolic process IEP Predicted GO
BP GO:0042176 regulation of protein catabolic process IEP Predicted GO
BP GO:0042440 pigment metabolic process IEP Predicted GO
CC GO:0042555 MCM complex IEP Predicted GO
BP GO:0042724 thiamine-containing compound biosynthetic process IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043233 organelle lumen IEP Predicted GO
BP GO:0043248 proteasome assembly IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
BP GO:0043648 dicarboxylic acid metabolic process IEP Predicted GO
BP GO:0043933 protein-containing complex subunit organization IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044265 cellular macromolecule catabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044429 mitochondrial part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044455 mitochondrial membrane part IEP Predicted GO
BP GO:0045116 protein neddylation IEP Predicted GO
CC GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) IEP Predicted GO
CC GO:0045267 proton-transporting ATP synthase, catalytic core IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046036 CTP metabolic process IEP Predicted GO
BP GO:0046039 GTP metabolic process IEP Predicted GO
BP GO:0046051 UTP metabolic process IEP Predicted GO
BP GO:0046149 pigment catabolic process IEP Predicted GO
BP GO:0046160 heme a metabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046416 D-amino acid metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046653 tetrahydrofolate metabolic process IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
BP GO:0046942 carboxylic acid transport IEP Predicted GO
MF GO:0046943 carboxylic acid transmembrane transporter activity IEP Predicted GO
BP GO:0051131 chaperone-mediated protein complex assembly IEP Predicted GO
BP GO:0051181 cofactor transport IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051187 cofactor catabolic process IEP Predicted GO
BP GO:0051382 kinetochore assembly IEP Predicted GO
BP GO:0051383 kinetochore organization IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
BP GO:0051604 protein maturation IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0065003 protein-containing complex assembly IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
CC GO:0070013 intracellular organelle lumen IEP Predicted GO
BP GO:0070178 D-serine metabolic process IEP Predicted GO
BP GO:0070682 proteasome regulatory particle assembly IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0072350 tricarboxylic acid metabolic process IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072593 reactive oxygen species metabolic process IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
BP GO:0098655 cation transmembrane transport IEP Predicted GO
BP GO:0098660 inorganic ion transmembrane transport IEP Predicted GO
BP GO:0098662 inorganic cation transmembrane transport IEP Predicted GO
CC GO:0098798 mitochondrial protein complex IEP Predicted GO
CC GO:0098800 inner mitochondrial membrane protein complex IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901565 organonitrogen compound catabolic process IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1901605 alpha-amino acid metabolic process IEP Predicted GO
BP GO:1901607 alpha-amino acid biosynthetic process IEP Predicted GO
CC GO:1902494 catalytic complex IEP Predicted GO
BP GO:1902600 proton transmembrane transport IEP Predicted GO
CC GO:1905368 peptidase complex IEP Predicted GO
CC GO:1905369 endopeptidase complex IEP Predicted GO
CC GO:1990204 oxidoreductase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR023753 FAD/NAD-binding_dom 659 990
IPR023753 FAD/NAD-binding_dom 118 449
IPR004099 Pyr_nucl-diS_OxRdtase_dimer 1010 1134
IPR004099 Pyr_nucl-diS_OxRdtase_dimer 469 593
PlasmoDB 813514
PlasmoDB PFI1170c