PF3D7_0927300 (FH)

Aliases : FH

Description : SSF117457: "Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily". Pfam domain(s): PF05683: Fumarase C-terminus, PF05681: Fumarate hydratase (Fumerase).

Gene families : OG_01_0002624 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002624_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0927300
Cluster	P. falciparum: Cluster_34

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004333	fumarate hydratase activity	IMP	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	IMP	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006106	fumarate metabolic process	IDA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016829	lyase activity	IEA	Interproscan predictions
MF	GO:0016829	lyase activity	IEA	PlasmoDB
MF	GO:0016835	carbon-oxygen lyase activity	None	Extended
MF	GO:0016836	hydro-lyase activity	IEA	Interproscan predictions
MF	GO:0016836	hydro-lyase activity	IEA	PlasmoDB
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0043648	dicarboxylic acid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Predicted GO
BP	GO:0000278	mitotic cell cycle	IEP	Predicted GO
CC	GO:0000796	condensin complex	IEP	Predicted GO
BP	GO:0002376	immune system process	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity	IEP	Predicted GO
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004775	succinate-CoA ligase (ADP-forming) activity	IEP	Predicted GO
MF	GO:0005375	copper ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005750	mitochondrial respiratory chain complex III	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005814	centriole	IEP	Predicted GO
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006116	NADH oxidation	IEP	Predicted GO
BP	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	IEP	Predicted GO
BP	GO:0006127	glycerophosphate shuttle	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006308	DNA catabolic process	IEP	Predicted GO
BP	GO:0006323	DNA packaging	IEP	Predicted GO
BP	GO:0006410	obsolete transcription, RNA-dependent	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006733	oxidoreduction coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006734	NADH metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006825	copper ion transport	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007029	endoplasmic reticulum organization	IEP	Predicted GO
BP	GO:0007049	cell cycle	IEP	Predicted GO
BP	GO:0007051	spindle organization	IEP	Predicted GO
BP	GO:0007052	mitotic spindle organization	IEP	Predicted GO
BP	GO:0007076	mitotic chromosome condensation	IEP	Predicted GO
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
CC	GO:0009331	glycerol-3-phosphate dehydrogenase complex	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0015074	DNA integration	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Predicted GO
MF	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	IEP	Predicted GO
BP	GO:0018143	nucleic acid-protein covalent cross-linking	IEP	Predicted GO
BP	GO:0018144	RNA-protein covalent cross-linking	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019439	aromatic compound catabolic process	IEP	Predicted GO
BP	GO:0019674	NAD metabolic process	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
BP	GO:0022402	cell cycle process	IEP	Predicted GO
BP	GO:0030001	metal ion transport	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
BP	GO:0030261	chromosome condensation	IEP	Predicted GO
MF	GO:0031079	obsolete picornain 3C activity	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0034308	primary alcohol metabolic process	IEP	Predicted GO
BP	GO:0034655	nucleobase-containing compound catabolic process	IEP	Predicted GO
BP	GO:0035434	copper ion transmembrane transport	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0044270	cellular nitrogen compound catabolic process	IEP	Predicted GO
CC	GO:0044450	microtubule organizing center part	IEP	Predicted GO
CC	GO:0045275	respiratory chain complex III	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
BP	GO:0046700	heterocycle catabolic process	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0046915	transition metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0051301	cell division	IEP	Predicted GO
BP	GO:0052646	alditol phosphate metabolic process	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
CC	GO:0070069	cytochrome complex	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
CC	GO:0071782	endoplasmic reticulum tubular network	IEP	Predicted GO
BP	GO:0071786	endoplasmic reticulum tubular network organization	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
CC	GO:0098827	endoplasmic reticulum subcompartment	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901361	organic cyclic compound catabolic process	IEP	Predicted GO
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO
CC	GO:1990204	oxidoreductase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004647	Fe-S_hydro-lyase_TtdB-typ_cat	470	678
IPR004646	Fe-S_hydro-lyase_TtdA-typ_cat	132	464

External Links

PlasmoDB	813548
PlasmoDB	PFI1340w

PF3D7_0927300 (FH)

Expression Profile

Co-expression Networks

Functional Annotation