PF3D7_1013500 (PI-PLC)

Aliases : PI-PLC

Description : SSF51695: "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily", SSF50729: No description available, SSF49562: No description available. Pfam domain(s): PF00387: "Phosphatidylinositol-specific phospholipase C, Y domain", PF00388: "Phosphatidylinositol-specific phospholipase C, X domain", PF12814: Meiotic cell cortex C-terminal pleckstrin homology.

Gene families : OG_01_0001603 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001603_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1013500
Cluster	P. falciparum: Cluster_41

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004435	phosphatidylinositol phospholipase C activity	ISS	PlasmoDB
MF	GO:0004435	phosphatidylinositol phospholipase C activity	IEA	Interproscan predictions
MF	GO:0004435	phosphatidylinositol phospholipase C activity	IEA	PlasmoDB
MF	GO:0004620	phospholipase activity	None	Extended
MF	GO:0004629	phospholipase C activity	None	Extended
MF	GO:0004629	phospholipase C activity	ISS	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan predictions
MF	GO:0005515	protein binding	IEA	PlasmoDB
MF	GO:0005543	phospholipid binding	IEA	Interproscan predictions
MF	GO:0005543	phospholipid binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	None	Extended
CC	GO:0005938	cell cortex	IEA	Interproscan predictions
CC	GO:0005938	cell cortex	IEA	PlasmoDB
BP	GO:0006629	lipid metabolic process	IEA	Interproscan predictions
BP	GO:0006629	lipid metabolic process	IEA	PlasmoDB
BP	GO:0006644	phospholipid metabolic process	ISS	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0007165	signal transduction	IEA	Interproscan predictions
BP	GO:0007165	signal transduction	IEA	PlasmoDB
MF	GO:0008081	phosphoric diester hydrolase activity	None	Extended
MF	GO:0008081	phosphoric diester hydrolase activity	IEA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008289	lipid binding	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016298	lipase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0032065	cortical protein anchoring	IEA	Interproscan predictions
BP	GO:0032065	cortical protein anchoring	IEA	PlasmoDB
BP	GO:0032507	maintenance of protein location in cell	None	Extended
BP	GO:0035556	intracellular signal transduction	ISS	PlasmoDB
BP	GO:0035556	intracellular signal transduction	IEA	Interproscan predictions
BP	GO:0035556	intracellular signal transduction	IEA	PlasmoDB
MF	GO:0042578	phosphoric ester hydrolase activity	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045185	maintenance of protein location	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051235	maintenance of location	None	Extended
BP	GO:0051651	maintenance of location in cell	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0099568	cytoplasmic region	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000226	microtubule cytoskeleton organization	IEP	Predicted GO
CC	GO:0000922	spindle pole	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0003896	DNA primase activity	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006261	DNA-dependent DNA replication	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006891	intra-Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0007020	microtubule nucleation	IEP	Predicted GO
CC	GO:0008622	epsilon DNA polymerase complex	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0015977	carbon fixation	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016984	ribulose-bisphosphate carboxylase activity	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
CC	GO:0042575	DNA polymerase complex	IEP	Predicted GO
MF	GO:0043015	gamma-tubulin binding	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001711	PLipase_C_Pinositol-sp_Y	979	1084
IPR000909	PLipase_C_PInositol-sp_X_dom	626	769
IPR024774	PH_dom-Mcp5-type	87	199

External Links

PlasmoDB	810290
PlasmoDB	PF10_0132

PF3D7_1013500 (PI-PLC)

Expression Profile

Co-expression Networks

Functional Annotation