PF3D7_1015200 (CysRS)

Aliases : CysRS

Description : SSF52374: No description available, SSF47323: "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding". Pfam domain(s): PF01406: tRNA synthetases class I (C) catalytic domain.

Gene families : OG_01_0001612 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001612_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1015200
Cluster	P. falciparum: Cluster_4

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0004817	cysteine-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005829	cytosol	IDA	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	PlasmoDB
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEA	PlasmoDB
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
CC	GO:0020011	apicoplast	RCA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000380	alternative mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0001906	cell killing	IEP	Predicted GO
BP	GO:0002181	cytoplasmic translation	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003713	transcription coactivator activity	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Predicted GO
MF	GO:0004462	lactoylglutathione lyase activity	IEP	Predicted GO
MF	GO:0004526	ribonuclease P activity	IEP	Predicted GO
MF	GO:0004549	tRNA-specific ribonuclease activity	IEP	Predicted GO
MF	GO:0004576	oligosaccharyl transferase activity	IEP	Predicted GO
MF	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005681	spliceosomal complex	IEP	Predicted GO
CC	GO:0005688	U6 snRNP	IEP	Predicted GO
CC	GO:0005853	eukaryotic translation elongation factor 1 complex	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006487	protein N-linked glycosylation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006749	glutathione metabolic process	IEP	Predicted GO
BP	GO:0006884	cell volume homeostasis	IEP	Predicted GO
MF	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	IEP	Predicted GO
CC	GO:0008250	oligosaccharyltransferase complex	IEP	Predicted GO
BP	GO:0008361	regulation of cell size	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
CC	GO:0009331	glycerol-3-phosphate dehydrogenase complex	IEP	Predicted GO
BP	GO:0009889	regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0010468	regulation of gene expression	IEP	Predicted GO
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0015037	peptide disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015038	glutathione disulfide oxidoreductase activity	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016846	carbon-sulfur lyase activity	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0019222	regulation of metabolic process	IEP	Predicted GO
BP	GO:0019835	cytolysis	IEP	Predicted GO
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predicted GO
CC	GO:0030430	host cell cytoplasm	IEP	Predicted GO
CC	GO:0030677	ribonuclease P complex	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0031640	killing of cells of other organism	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
BP	GO:0043484	regulation of RNA splicing	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
CC	GO:0043657	host cell	IEP	Predicted GO
BP	GO:0044179	hemolysis in other organism	IEP	Predicted GO
CC	GO:0044216	other organism cell	IEP	Predicted GO
BP	GO:0044364	disruption of cells of other organism	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
BP	GO:0044764	multi-organism cellular process	IEP	Predicted GO
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Predicted GO
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0050684	regulation of mRNA processing	IEP	Predicted GO
BP	GO:0050794	regulation of cellular process	IEP	Predicted GO
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051715	cytolysis in other organism	IEP	Predicted GO
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0080090	regulation of primary metabolic process	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
BP	GO:1903311	regulation of mRNA metabolic process	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR032678	tRNA-synt_1_cat_dom	1391	1691
IPR032678	tRNA-synt_1_cat_dom	122	422
IPR032678	tRNA-synt_1_cat_dom	798	1098

External Links

PlasmoDB	810307
PlasmoDB	PF10_0149

PF3D7_1015200 (CysRS)

Expression Profile

Co-expression Networks

Functional Annotation