PF3D7_1020900 (ARF1)

Aliases : ARF1

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00025: ADP-ribosylation factor family.

Gene families : OG_01_0000095 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000095_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1020900
Cluster	P. falciparum: Cluster_42

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0505100	ARF1	SSF52540: P-loop containing nucleoside triphosphate...	0.05	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
CC	GO:0000323	lytic vacuole	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IDA	PlasmoDB
MF	GO:0005525	GTP binding	IEA	Interproscan predictions
MF	GO:0005525	GTP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005622	intracellular	IEA	PlasmoDB
CC	GO:0005764	lysosome	None	Extended
CC	GO:0005767	secondary lysosome	None	Extended
CC	GO:0005773	vacuole	None	Extended
CC	GO:0005794	Golgi apparatus	IDA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006471	protein ADP-ribosylation	TAS	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006886	intracellular protein transport	IEA	PlasmoDB
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0020020	food vacuole	RCA	PlasmoDB
CC	GO:0030139	endocytic vesicle	None	Extended
CC	GO:0031410	cytoplasmic vesicle	None	Extended
CC	GO:0031982	vesicle	None	Extended
CC	GO:0032010	phagolysosome	None	Extended
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0042886	amide transport	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
CC	GO:0045335	phagocytic vesicle	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
CC	GO:0097708	intracellular vesicle	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000209	protein polyubiquitination	IEP	Predicted GO
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Predicted GO
CC	GO:0000785	chromatin	IEP	Predicted GO
CC	GO:0000786	nucleosome	IEP	Predicted GO
CC	GO:0000791	euchromatin	IEP	Predicted GO
BP	GO:0002376	immune system process	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
MF	GO:0003785	actin monomer binding	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0003924	GTPase activity	IEP	Predicted GO
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
MF	GO:0004475	mannose-1-phosphate guanylyltransferase activity	IEP	Predicted GO
MF	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	IEP	Predicted GO
MF	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005750	mitochondrial respiratory chain complex III	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IEP	Predicted GO
CC	GO:0005851	eukaryotic translation initiation factor 2B complex	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	IEP	Predicted GO
BP	GO:0006405	RNA export from nucleus	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006606	protein import into nucleus	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008521	acetyl-CoA transmembrane transporter activity	IEP	Predicted GO
CC	GO:0008541	proteasome regulatory particle, lid subcomplex	IEP	Predicted GO
MF	GO:0008905	mannose-phosphate guanylyltransferase activity	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009060	aerobic respiration	IEP	Predicted GO
BP	GO:0009226	nucleotide-sugar biosynthetic process	IEP	Predicted GO
BP	GO:0009298	GDP-mannose biosynthetic process	IEP	Predicted GO
BP	GO:0010243	response to organonitrogen compound	IEP	Predicted GO
BP	GO:0010498	proteasomal protein catabolic process	IEP	Predicted GO
BP	GO:0010564	regulation of cell cycle process	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015095	magnesium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Predicted GO
CC	GO:0015629	actin cytoskeleton	IEP	Predicted GO
BP	GO:0015693	magnesium ion transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Predicted GO
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
BP	GO:0019673	GDP-mannose metabolic process	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0022900	electron transport chain	IEP	Predicted GO
BP	GO:0022904	respiratory electron transport chain	IEP	Predicted GO
BP	GO:0030036	actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0030048	actin filament-based movement	IEP	Predicted GO
BP	GO:0030433	ubiquitin-dependent ERAD pathway	IEP	Predicted GO
BP	GO:0032879	regulation of localization	IEP	Predicted GO
CC	GO:0032993	protein-DNA complex	IEP	Predicted GO
BP	GO:0033365	protein localization to organelle	IEP	Predicted GO
BP	GO:0034504	protein localization to nucleus	IEP	Predicted GO
BP	GO:0034613	cellular protein localization	IEP	Predicted GO
BP	GO:0034976	response to endoplasmic reticulum stress	IEP	Predicted GO
BP	GO:0036503	ERAD pathway	IEP	Predicted GO
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044815	DNA packaging complex	IEP	Predicted GO
CC	GO:0045275	respiratory chain complex III	IEP	Predicted GO
BP	GO:0045333	cellular respiration	IEP	Predicted GO
MF	GO:0046872	metal ion binding	IEP	Predicted GO
MF	GO:0046982	protein heterodimerization activity	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050657	nucleic acid transport	IEP	Predicted GO
BP	GO:0050658	RNA transport	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
BP	GO:0050789	regulation of biological process	IEP	Predicted GO
BP	GO:0050794	regulation of cellular process	IEP	Predicted GO
BP	GO:0051014	actin filament severing	IEP	Predicted GO
BP	GO:0051049	regulation of transport	IEP	Predicted GO
BP	GO:0051168	nuclear export	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051170	import into nucleus	IEP	Predicted GO
MF	GO:0051184	cofactor transmembrane transporter activity	IEP	Predicted GO
MF	GO:0051185	coenzyme transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051236	establishment of RNA localization	IEP	Predicted GO
BP	GO:0051262	protein tetramerization	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
MF	GO:0051536	iron-sulfur cluster binding	IEP	Predicted GO
MF	GO:0051537	2 iron, 2 sulfur cluster binding	IEP	Predicted GO
MF	GO:0051540	metal cluster binding	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051726	regulation of cell cycle	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0060327	cytoplasmic actin-based contraction involved in cell motility	IEP	Predicted GO
BP	GO:0060627	regulation of vesicle-mediated transport	IEP	Predicted GO
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070252	actin-mediated cell contraction	IEP	Predicted GO
MF	GO:0070568	guanylyltransferase activity	IEP	Predicted GO
BP	GO:0070727	cellular macromolecule localization	IEP	Predicted GO
MF	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
BP	GO:0072594	establishment of protein localization to organelle	IEP	Predicted GO
CC	GO:0089701	U2AF	IEP	Predicted GO
MF	GO:0097472	cyclin-dependent protein kinase activity	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
MF	GO:1901682	sulfur compound transmembrane transporter activity	IEP	Predicted GO
BP	GO:1901698	response to nitrogen compound	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006689	Small_GTPase_ARF/SAR	7	175

External Links

PlasmoDB	810360
PlasmoDB	PF10_0203

PF3D7_1020900 (ARF1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation