PF3D7_1030000 (SPT4)

Aliases : SPT4

Description : SSF63393: RNA polymerase subunit RPABC4/transcription elongation factor Spt4. Pfam domain(s): PF06093: Spt4/RpoE2 zinc finger.

Gene families : OG_01_0000712 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000712_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1030000
Cluster	P. falciparum: Cluster_23

Type	GO Term	Name	Evidence	Source
MF	GO:0000182	rDNA binding	ISS	PlasmoDB
BP	GO:0000375	RNA splicing, via transesterification reactions	None	Extended
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	None	Extended
BP	GO:0000398	mRNA splicing, via spliceosome	ISS	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006355	regulation of transcription, DNA-templated	ISS	PlasmoDB
BP	GO:0006355	regulation of transcription, DNA-templated	IEA	PlasmoDB
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006397	mRNA processing	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	PlasmoDB
BP	GO:0008380	RNA splicing	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009891	positive regulation of biosynthetic process	None	Extended
BP	GO:0009893	positive regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010557	positive regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010604	positive regulation of macromolecule metabolic process	None	Extended
BP	GO:0010628	positive regulation of gene expression	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016071	mRNA metabolic process	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031325	positive regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0031328	positive regulation of cellular biosynthetic process	None	Extended
BP	GO:0032784	regulation of DNA-templated transcription, elongation	None	Extended
BP	GO:0032786	positive regulation of DNA-templated transcription, elongation	IEA	PlasmoDB
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
MF	GO:0043565	sequence-specific DNA binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045893	positive regulation of transcription, DNA-templated	None	Extended
BP	GO:0045935	positive regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0048518	positive regulation of biological process	None	Extended
BP	GO:0048522	positive regulation of cellular process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0051254	positive regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1902680	positive regulation of RNA biosynthetic process	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:1903508	positive regulation of nucleic acid-templated transcription	None	Extended
MF	GO:1990837	sequence-specific double-stranded DNA binding	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
CC	GO:0000786	nucleosome	IEP	Predicted GO
BP	GO:0003006	developmental process involved in reproduction	IEP	Predicted GO
MF	GO:0004000	adenosine deaminase activity	IEP	Predicted GO
MF	GO:0004364	glutathione transferase activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0004857	enzyme inhibitor activity	IEP	Predicted GO
MF	GO:0004864	protein phosphatase inhibitor activity	IEP	Predicted GO
MF	GO:0004865	protein serine/threonine phosphatase inhibitor activity	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005682	U5 snRNP	IEP	Predicted GO
CC	GO:0005685	U1 snRNP	IEP	Predicted GO
CC	GO:0005784	Sec61 translocon complex	IEP	Predicted GO
CC	GO:0005850	eukaryotic translation initiation factor 2 complex	IEP	Predicted GO
BP	GO:0006325	chromatin organization	IEP	Predicted GO
BP	GO:0006333	chromatin assembly or disassembly	IEP	Predicted GO
BP	GO:0006334	nucleosome assembly	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Predicted GO
BP	GO:0006749	glutathione metabolic process	IEP	Predicted GO
BP	GO:0007530	sex determination	IEP	Predicted GO
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0010563	negative regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0010921	regulation of phosphatase activity	IEP	Predicted GO
BP	GO:0010923	negative regulation of phosphatase activity	IEP	Predicted GO
MF	GO:0016298	lipase activity	IEP	Predicted GO
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
MF	GO:0019212	phosphatase inhibitor activity	IEP	Predicted GO
BP	GO:0019220	regulation of phosphate metabolic process	IEP	Predicted GO
MF	GO:0019239	deaminase activity	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0020026	merozoite dense granule	IEP	Predicted GO
BP	GO:0022414	reproductive process	IEP	Predicted GO
MF	GO:0030515	snoRNA binding	IEP	Predicted GO
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Predicted GO
MF	GO:0031386	protein tag	IEP	Predicted GO
BP	GO:0031399	regulation of protein modification process	IEP	Predicted GO
BP	GO:0031400	negative regulation of protein modification process	IEP	Predicted GO
BP	GO:0032269	negative regulation of cellular protein metabolic process	IEP	Predicted GO
BP	GO:0032502	developmental process	IEP	Predicted GO
BP	GO:0032515	negative regulation of phosphoprotein phosphatase activity	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0032993	protein-DNA complex	IEP	Predicted GO
BP	GO:0034728	nucleosome organization	IEP	Predicted GO
CC	GO:0035145	exon-exon junction complex	IEP	Predicted GO
BP	GO:0035303	regulation of dephosphorylation	IEP	Predicted GO
BP	GO:0035304	regulation of protein dephosphorylation	IEP	Predicted GO
BP	GO:0035305	negative regulation of dephosphorylation	IEP	Predicted GO
BP	GO:0035308	negative regulation of protein dephosphorylation	IEP	Predicted GO
MF	GO:0042393	histone binding	IEP	Predicted GO
BP	GO:0043086	negative regulation of catalytic activity	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0043666	regulation of phosphoprotein phosphatase activity	IEP	Predicted GO
BP	GO:0043952	protein transport by the Sec complex	IEP	Predicted GO
BP	GO:0044092	negative regulation of molecular function	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044815	DNA packaging complex	IEP	Predicted GO
BP	GO:0045936	negative regulation of phosphate metabolic process	IEP	Predicted GO
CC	GO:0046540	U4/U6 x U5 tri-snRNP complex	IEP	Predicted GO
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051174	regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0051248	negative regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051336	regulation of hydrolase activity	IEP	Predicted GO
BP	GO:0051346	negative regulation of hydrolase activity	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0065004	protein-DNA complex assembly	IEP	Predicted GO
CC	GO:0070971	endoplasmic reticulum exit site	IEP	Predicted GO
CC	GO:0071256	translocon complex	IEP	Predicted GO
BP	GO:0071824	protein-DNA complex subunit organization	IEP	Predicted GO
CC	GO:0097526	spliceosomal tri-snRNP complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR022800	Spt4/RpoE2_Znf	43	118

External Links

PlasmoDB	810450
PlasmoDB	PF10_0293

PF3D7_1030000 (SPT4)

Expression Profile

Co-expression Networks

Functional Annotation