PF3D7_1034400 (SDHA)

Aliases : SDHA

Description : SSF46977: "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily", SSF56425: "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily", SSF51905: FAD/NAD(P)-binding domain superfamily. Pfam domain(s): PF02910: Fumarate reductase flavoprotein C-term, PF00890: FAD binding domain.

Gene families : OG_01_0000734 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000734_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1034400
Cluster	P. falciparum: Cluster_17

Type	GO Term	Name	Evidence	Source
MF	GO:0000104	succinate dehydrogenase activity	None	Extended
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	IDA	PlasmoDB
CC	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	ISS	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006091	generation of precursor metabolites and energy	None	Extended
BP	GO:0006099	tricarboxylic acid cycle	IMP	PlasmoDB
BP	GO:0006099	tricarboxylic acid cycle	IEA	PlasmoDB
BP	GO:0006101	citrate metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008177	succinate dehydrogenase (ubiquinone) activity	ISS	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	Interproscan predictions
MF	GO:0016491	oxidoreductase activity	IEA	PlasmoDB
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEA	PlasmoDB
MF	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	None	Extended
BP	GO:0016999	antibiotic metabolic process	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0022900	electron transport chain	IEA	PlasmoDB
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044429	mitochondrial part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044455	mitochondrial membrane part	None	Extended
CC	GO:0044464	cell part	None	Extended
CC	GO:0045257	succinate dehydrogenase complex (ubiquinone)	None	Extended
CC	GO:0045281	succinate dehydrogenase complex	None	Extended
CC	GO:0045283	fumarate reductase complex	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050660	flavin adenine dinucleotide binding	IEA	PlasmoDB
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan predictions
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072350	tricarboxylic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0098796	membrane protein complex	None	Extended
CC	GO:0098798	mitochondrial protein complex	None	Extended
CC	GO:0098800	inner mitochondrial membrane protein complex	None	Extended
CC	GO:0098803	respiratory chain complex	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990204	oxidoreductase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000314	organellar small ribosomal subunit	IEP	Predicted GO
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Predicted GO
MF	GO:0004222	metalloendopeptidase activity	IEP	Predicted GO
MF	GO:0004683	calmodulin-dependent protein kinase activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005763	mitochondrial small ribosomal subunit	IEP	Predicted GO
BP	GO:0006405	RNA export from nucleus	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006816	calcium ion transport	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
BP	GO:0006986	response to unfolded protein	IEP	Predicted GO
MF	GO:0008273	calcium, potassium:sodium antiporter activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
MF	GO:0015079	potassium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015291	secondary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015297	antiporter activity	IEP	Predicted GO
MF	GO:0015298	solute:cation antiporter activity	IEP	Predicted GO
MF	GO:0015299	solute:proton antiporter activity	IEP	Predicted GO
MF	GO:0015368	calcium:cation antiporter activity	IEP	Predicted GO
MF	GO:0015369	calcium:proton antiporter activity	IEP	Predicted GO
MF	GO:0015491	cation:cation antiporter activity	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
MF	GO:0016018	cyclosporin A binding	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
MF	GO:0022821	potassium ion antiporter activity	IEP	Predicted GO
MF	GO:0030544	Hsp70 protein binding	IEP	Predicted GO
MF	GO:0031072	heat shock protein binding	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0035966	response to topologically incorrect protein	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
MF	GO:0042277	peptide binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0043248	proteasome assembly	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0050657	nucleic acid transport	IEP	Predicted GO
BP	GO:0050658	RNA transport	IEP	Predicted GO
MF	GO:0051139	metal ion:proton antiporter activity	IEP	Predicted GO
BP	GO:0051168	nuclear export	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051236	establishment of RNA localization	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
BP	GO:0072511	divalent inorganic cation transport	IEP	Predicted GO
MF	GO:0099516	ion antiporter activity	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR015939	Fum_Rdtase/Succ_DH_flav-like_C	494	631
IPR003953	FAD-binding_2	35	439

External Links

PlasmoDB	810491
PlasmoDB	PF10_0334

PF3D7_1034400 (SDHA)

Expression Profile

Co-expression Networks

Functional Annotation