PF3D7_1034900 (MRScyt)

Aliases : MRScyt

Description : SSF52374: No description available, SSF47616: "Glutathione S-transferase, C-terminal domain superfamily", SSF47323: "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding". Pfam domain(s): PF09334: tRNA synthetases class I (M).

Gene families : OG_01_0000735 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000735_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1034900
Cluster	P. falciparum: Cluster_48

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan predictions
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan predictions
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0004825	methionine-tRNA ligase activity	IDA	PlasmoDB
MF	GO:0004825	methionine-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	ISS	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan predictions
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	PlasmoDB
BP	GO:0006431	methionyl-tRNA aminoacylation	IDA	PlasmoDB
BP	GO:0006431	methionyl-tRNA aminoacylation	IEA	PlasmoDB
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000234	phosphoethanolamine N-methyltransferase activity	IEP	Predicted GO
CC	GO:0000502	proteasome complex	IEP	Predicted GO
BP	GO:0001678	cellular glucose homeostasis	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003689	DNA clamp loader activity	IEP	Predicted GO
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0004000	adenosine deaminase activity	IEP	Predicted GO
MF	GO:0004013	adenosylhomocysteinase activity	IEP	Predicted GO
MF	GO:0004017	adenylate kinase activity	IEP	Predicted GO
MF	GO:0004170	dUTP diphosphatase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004396	hexokinase activity	IEP	Predicted GO
MF	GO:0004448	isocitrate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004450	isocitrate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0004791	thioredoxin-disulfide reductase activity	IEP	Predicted GO
MF	GO:0004839	ubiquitin activating enzyme activity	IEP	Predicted GO
MF	GO:0005310	dicarboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005342	organic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005385	zinc ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005388	calcium-transporting ATPase activity	IEP	Predicted GO
MF	GO:0005536	glucose binding	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005798	Golgi-associated vesicle	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
CC	GO:0005956	protein kinase CK2 complex	IEP	Predicted GO
BP	GO:0006102	isocitrate metabolic process	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006272	leading strand elongation	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006627	protein processing involved in protein targeting to mitochondrion	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006656	phosphatidylcholine biosynthetic process	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006816	calcium ion transport	IEP	Predicted GO
BP	GO:0006829	zinc ion transport	IEP	Predicted GO
BP	GO:0006835	dicarboxylic acid transport	IEP	Predicted GO
BP	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IEP	Predicted GO
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008509	anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0008535	respiratory chain complex IV assembly	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0009894	regulation of catabolic process	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015140	malate transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015367	oxoglutarate:malate antiporter activity	IEP	Predicted GO
MF	GO:0015556	C4-dicarboxylate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015740	C4-dicarboxylate transport	IEP	Predicted GO
BP	GO:0015742	alpha-ketoglutarate transport	IEP	Predicted GO
BP	GO:0015743	malate transport	IEP	Predicted GO
BP	GO:0015849	organic acid transport	IEP	Predicted GO
MF	GO:0016208	AMP binding	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016801	hydrolase activity, acting on ether bonds	IEP	Predicted GO
MF	GO:0016802	trialkylsulfonium hydrolase activity	IEP	Predicted GO
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
BP	GO:0017004	cytochrome complex assembly	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
BP	GO:0017062	respiratory chain complex III assembly	IEP	Predicted GO
CC	GO:0017087	mitochondrial processing peptidase complex	IEP	Predicted GO
CC	GO:0019005	SCF ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
MF	GO:0019239	deaminase activity	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
CC	GO:0019774	proteasome core complex, beta-subunit complex	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
BP	GO:0030001	metal ion transport	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	IEP	Predicted GO
CC	GO:0030135	coated vesicle	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
MF	GO:0030246	carbohydrate binding	IEP	Predicted GO
MF	GO:0030337	DNA polymerase processivity factor activity	IEP	Predicted GO
MF	GO:0030604	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
BP	GO:0032446	protein modification by small protein conjugation	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033108	mitochondrial respiratory chain complex assembly	IEP	Predicted GO
MF	GO:0033170	protein-DNA loading ATPase activity	IEP	Predicted GO
BP	GO:0033500	carbohydrate homeostasis	IEP	Predicted GO
BP	GO:0034551	mitochondrial respiratory chain complex III assembly	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034982	mitochondrial protein processing	IEP	Predicted GO
BP	GO:0042176	regulation of protein catabolic process	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0042593	glucose homeostasis	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044053	translocation of peptides or proteins into host cell cytoplasm	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
BP	GO:0045116	protein neddylation	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046470	phosphatidylcholine metabolic process	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
BP	GO:0046777	protein autophosphorylation	IEP	Predicted GO
MF	GO:0046872	metal ion binding	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0046942	carboxylic acid transport	IEP	Predicted GO
MF	GO:0046943	carboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Predicted GO
MF	GO:0048029	monosaccharide binding	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
MF	GO:0050661	NADP binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0051131	chaperone-mediated protein complex assembly	IEP	Predicted GO
BP	GO:0051181	cofactor transport	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
MF	GO:0070402	NADPH binding	IEP	Predicted GO
MF	GO:0070628	proteasome binding	IEP	Predicted GO
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
MF	GO:0072509	divalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0072511	divalent inorganic cation transport	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR015413	Methionyl/Leucyl_tRNA_Synth	374	579
IPR015413	Methionyl/Leucyl_tRNA_Synth	226	358

External Links

PlasmoDB	810497
PlasmoDB	PF10_0340

PF3D7_1034900 (MRScyt)

Expression Profile

Co-expression Networks

Functional Annotation