PF3D7_1107500

Description : SSF46579: No description available. Pfam domain(s): PF02996: Prefoldin subunit.

Gene families : OG_01_0002738 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002738_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1107500
Cluster	P. falciparum: Cluster_4

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0939400	No alias	SSF46579: 20-02-2019. Pfam domain(s): PF02996: Prefoldin subunit.	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
BP	GO:0000122	negative regulation of transcription by RNA polymerase II	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003712	transcription coregulator activity	None	Extended
MF	GO:0003714	transcription corepressor activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	PlasmoDB
BP	GO:0006355	regulation of transcription, DNA-templated	None	Extended
BP	GO:0006357	regulation of transcription by RNA polymerase II	None	Extended
BP	GO:0006457	protein folding	IEA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009890	negative regulation of biosynthetic process	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
CC	GO:0016272	prefoldin complex	IEA	PlasmoDB
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031324	negative regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0031327	negative regulation of cellular biosynthetic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045892	negative regulation of transcription, DNA-templated	None	Extended
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
MF	GO:0051082	unfolded protein binding	IEA	PlasmoDB
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0051253	negative regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0140110	transcription regulator activity	None	Extended
BP	GO:1902679	negative regulation of RNA biosynthetic process	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000175	3'-5'-exoribonuclease activity	IEP	Predicted GO
CC	GO:0000178	exosome (RNase complex)	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000380	alternative mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
CC	GO:0000439	transcription factor TFIIH core complex	IEP	Predicted GO
BP	GO:0001731	formation of translation preinitiation complex	IEP	Predicted GO
BP	GO:0002181	cytoplasmic translation	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0004385	guanylate kinase activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0004766	spermidine synthase activity	IEP	Predicted GO
MF	GO:0005261	cation channel activity	IEP	Predicted GO
MF	GO:0005262	calcium channel activity	IEP	Predicted GO
CC	GO:0005681	spliceosomal complex	IEP	Predicted GO
CC	GO:0005685	U1 snRNP	IEP	Predicted GO
CC	GO:0005850	eukaryotic translation initiation factor 2 complex	IEP	Predicted GO
CC	GO:0005851	eukaryotic translation initiation factor 2B complex	IEP	Predicted GO
CC	GO:0005853	eukaryotic translation elongation factor 1 complex	IEP	Predicted GO
CC	GO:0005868	cytoplasmic dynein complex	IEP	Predicted GO
BP	GO:0006109	regulation of carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006186	dGDP phosphorylation	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006413	translational initiation	IEP	Predicted GO
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Predicted GO
BP	GO:0006595	polyamine metabolic process	IEP	Predicted GO
BP	GO:0006596	polyamine biosynthetic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006874	cellular calcium ion homeostasis	IEP	Predicted GO
BP	GO:0006875	cellular metal ion homeostasis	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
BP	GO:0008216	spermidine metabolic process	IEP	Predicted GO
BP	GO:0008295	spermidine biosynthetic process	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009151	purine deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009182	purine deoxyribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009186	deoxyribonucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009216	purine deoxyribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009308	amine metabolic process	IEP	Predicted GO
BP	GO:0009309	amine biosynthetic process	IEP	Predicted GO
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0010322	regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0010323	negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0010563	negative regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0010565	regulation of cellular ketone metabolic process	IEP	Predicted GO
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0010677	negative regulation of cellular carbohydrate metabolic process	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
MF	GO:0016018	cyclosporin A binding	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
BP	GO:0016311	dephosphorylation	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
MF	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
MF	GO:0019203	carbohydrate phosphatase activity	IEP	Predicted GO
MF	GO:0019206	nucleoside kinase activity	IEP	Predicted GO
BP	GO:0019216	regulation of lipid metabolic process	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019747	regulation of isoprenoid metabolic process	IEP	Predicted GO
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predicted GO
CC	GO:0030121	AP-1 adaptor complex	IEP	Predicted GO
CC	GO:0030176	integral component of endoplasmic reticulum membrane	IEP	Predicted GO
CC	GO:0030532	small nuclear ribonucleoprotein complex	IEP	Predicted GO
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	IEP	Predicted GO
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0034975	protein folding in endoplasmic reticulum	IEP	Predicted GO
BP	GO:0042401	cellular biogenic amine biosynthetic process	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044106	cellular amine metabolic process	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
BP	GO:0045827	negative regulation of isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0045833	negative regulation of lipid metabolic process	IEP	Predicted GO
BP	GO:0045912	negative regulation of carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0045936	negative regulation of phosphate metabolic process	IEP	Predicted GO
BP	GO:0046066	dGDP metabolic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0046890	regulation of lipid biosynthetic process	IEP	Predicted GO
MF	GO:0050145	nucleoside monophosphate kinase activity	IEP	Predicted GO
MF	GO:0050308	sugar-phosphatase activity	IEP	Predicted GO
MF	GO:0050661	NADP binding	IEP	Predicted GO
BP	GO:0051055	negative regulation of lipid biosynthetic process	IEP	Predicted GO
BP	GO:0055065	metal ion homeostasis	IEP	Predicted GO
BP	GO:0055074	calcium ion homeostasis	IEP	Predicted GO
BP	GO:0062012	regulation of small molecule metabolic process	IEP	Predicted GO
BP	GO:0062014	negative regulation of small molecule metabolic process	IEP	Predicted GO
BP	GO:0071071	regulation of phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0071072	negative regulation of phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0072503	cellular divalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0072507	divalent inorganic cation homeostasis	IEP	Predicted GO
CC	GO:0072546	ER membrane protein complex	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
CC	GO:0097525	spliceosomal snRNP complex	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
CC	GO:0120114	Sm-like protein family complex	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
BP	GO:1903725	regulation of phospholipid metabolic process	IEP	Predicted GO
BP	GO:1903726	negative regulation of phospholipid metabolic process	IEP	Predicted GO
CC	GO:1905354	exoribonuclease complex	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004127	Prefoldin_subunit_alpha	37	152

External Links

PlasmoDB	810639
PlasmoDB	PF11_0088

PF3D7_1107500

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation