PF3D7_1111100 (RFC5)

Aliases : RFC5

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF13177: "DNA polymerase III, delta subunit".

Gene families : OG_01_0001174 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001174_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1111100
Cluster	P. falciparum: Cluster_43

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0936500	RFC5	SSF52540: P-loop containing nucleoside triphosphate...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISS	PlasmoDB
CC	GO:0005663	DNA replication factor C complex	ISS	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	ISS	PlasmoDB
BP	GO:0006271	DNA strand elongation involved in DNA replication	ISS	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0022616	DNA strand elongation	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044427	chromosomal part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000036	acyl carrier activity	IEP	Predicted GO
MF	GO:0000062	fatty-acyl-CoA binding	IEP	Predicted GO
MF	GO:0000225	N-acetylglucosaminylphosphatidylinositol deacetylase activity	IEP	Predicted GO
MF	GO:0000234	phosphoethanolamine N-methyltransferase activity	IEP	Predicted GO
CC	GO:0000313	organellar ribosome	IEP	Predicted GO
CC	GO:0000502	proteasome complex	IEP	Predicted GO
CC	GO:0000792	heterochromatin	IEP	Predicted GO
MF	GO:0003674	molecular_function	IEP	Predicted GO
MF	GO:0003689	DNA clamp loader activity	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0004000	adenosine deaminase activity	IEP	Predicted GO
MF	GO:0004170	dUTP diphosphatase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004222	metalloendopeptidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004448	isocitrate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004450	isocitrate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004602	glutathione peroxidase activity	IEP	Predicted GO
MF	GO:0005310	dicarboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005342	organic acid transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005672	transcription factor TFIIA complex	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005761	mitochondrial ribosome	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
CC	GO:0005956	protein kinase CK2 complex	IEP	Predicted GO
BP	GO:0006102	isocitrate metabolic process	IEP	Predicted GO
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Predicted GO
BP	GO:0006272	leading strand elongation	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006333	chromatin assembly or disassembly	IEP	Predicted GO
BP	GO:0006458	'de novo' protein folding	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006627	protein processing involved in protein targeting to mitochondrion	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006631	fatty acid metabolic process	IEP	Predicted GO
BP	GO:0006633	fatty acid biosynthetic process	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006729	tetrahydrobiopterin biosynthetic process	IEP	Predicted GO
BP	GO:0006835	dicarboxylic acid transport	IEP	Predicted GO
MF	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008237	metallopeptidase activity	IEP	Predicted GO
BP	GO:0008283	cell proliferation	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
MF	GO:0008379	thioredoxin peroxidase activity	IEP	Predicted GO
MF	GO:0008509	anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
BP	GO:0008654	phospholipid biosynthetic process	IEP	Predicted GO
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEP	Predicted GO
MF	GO:0008897	holo-[acyl-carrier-protein] synthase activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0015074	DNA integration	IEP	Predicted GO
MF	GO:0015140	malate transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015367	oxoglutarate:malate antiporter activity	IEP	Predicted GO
MF	GO:0015556	C4-dicarboxylate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015740	C4-dicarboxylate transport	IEP	Predicted GO
BP	GO:0015742	alpha-ketoglutarate transport	IEP	Predicted GO
BP	GO:0015743	malate transport	IEP	Predicted GO
BP	GO:0015849	organic acid transport	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
BP	GO:0016485	protein processing	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEP	Predicted GO
BP	GO:0017062	respiratory chain complex III assembly	IEP	Predicted GO
CC	GO:0017087	mitochondrial processing peptidase complex	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
MF	GO:0019239	deaminase activity	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
MF	GO:0030337	DNA polymerase processivity factor activity	IEP	Predicted GO
MF	GO:0030604	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	IEP	Predicted GO
BP	GO:0031935	regulation of chromatin silencing	IEP	Predicted GO
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0033108	mitochondrial respiratory chain complex assembly	IEP	Predicted GO
MF	GO:0033170	protein-DNA loading ATPase activity	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0034311	diol metabolic process	IEP	Predicted GO
BP	GO:0034312	diol biosynthetic process	IEP	Predicted GO
BP	GO:0034551	mitochondrial respiratory chain complex III assembly	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034982	mitochondrial protein processing	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
MF	GO:0044620	ACP phosphopantetheine attachment site binding	IEP	Predicted GO
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Predicted GO
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Predicted GO
BP	GO:0046146	tetrahydrobiopterin metabolic process	IEP	Predicted GO
BP	GO:0046474	glycerophospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0046777	protein autophosphorylation	IEP	Predicted GO
BP	GO:0046942	carboxylic acid transport	IEP	Predicted GO
MF	GO:0046943	carboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051131	chaperone-mediated protein complex assembly	IEP	Predicted GO
BP	GO:0051181	cofactor transport	IEP	Predicted GO
MF	GO:0051192	prosthetic group binding	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051604	protein maturation	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0060968	regulation of gene silencing	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070070	proton-transporting V-type ATPase complex assembly	IEP	Predicted GO
BP	GO:0070071	proton-transporting two-sector ATPase complex assembly	IEP	Predicted GO
BP	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	IEP	Predicted GO
MF	GO:0070402	NADPH binding	IEP	Predicted GO
MF	GO:0070628	proteasome binding	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
MF	GO:1901567	fatty acid derivative binding	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO
BP	GO:1902275	regulation of chromatin organization	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO

No InterPro domains available for this sequence

External Links

PlasmoDB	810666
PlasmoDB	PF11_0117

PF3D7_1111100 (RFC5)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation