PF3D7_1117700 (RAN)

Aliases : RAN

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00071: Ras family.

Gene families : OG_01_0001156 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001156_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1117700
Cluster	P. falciparum: Cluster_30

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003924	GTPase activity	ISS	PlasmoDB
MF	GO:0003924	GTPase activity	IEA	Interproscan predictions
MF	GO:0003924	GTPase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	ISS	PlasmoDB
MF	GO:0005525	GTP binding	IEA	Interproscan predictions
MF	GO:0005525	GTP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISS	PlasmoDB
BP	GO:0006405	RNA export from nucleus	ISS	PlasmoDB
BP	GO:0006810	transport	None	Extended
BP	GO:0006886	intracellular protein transport	ISS	PlasmoDB
BP	GO:0006913	nucleocytoplasmic transport	IEA	PlasmoDB
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
BP	GO:0015931	nucleobase-containing compound transport	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
CC	GO:0031982	vesicle	None	Extended
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042886	amide transport	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043230	extracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044421	extracellular region part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
BP	GO:0050657	nucleic acid transport	None	Extended
BP	GO:0050658	RNA transport	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051168	nuclear export	None	Extended
BP	GO:0051169	nuclear transport	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051236	establishment of RNA localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0051726	regulation of cell cycle	ISS	PlasmoDB
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1903561	extracellular vesicle	RCA	PlasmoDB

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
MF	GO:0000104	succinate dehydrogenase activity	IEP	Predicted GO
CC	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
CC	GO:0000314	organellar small ribosomal subunit	IEP	Predicted GO
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
BP	GO:0000338	protein deneddylation	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003785	actin monomer binding	IEP	Predicted GO
MF	GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	IEP	Predicted GO
MF	GO:0004221	obsolete ubiquitin thiolesterase activity	IEP	Predicted GO
MF	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	IEP	Predicted GO
MF	GO:0004601	peroxidase activity	IEP	Predicted GO
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005663	DNA replication factor C complex	IEP	Predicted GO
CC	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	IEP	Predicted GO
CC	GO:0005763	mitochondrial small ribosomal subunit	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005773	vacuole	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005851	eukaryotic translation initiation factor 2B complex	IEP	Predicted GO
BP	GO:0006099	tricarboxylic acid cycle	IEP	Predicted GO
BP	GO:0006101	citrate metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006471	protein ADP-ribosylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006606	protein import into nucleus	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006816	calcium ion transport	IEP	Predicted GO
BP	GO:0006873	cellular ion homeostasis	IEP	Predicted GO
BP	GO:0006885	regulation of pH	IEP	Predicted GO
BP	GO:0007035	vacuolar acidification	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
MF	GO:0008177	succinate dehydrogenase (ubiquinone) activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
MF	GO:0008273	calcium, potassium:sodium antiporter activity	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
CC	GO:0008541	proteasome regulatory particle, lid subcomplex	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015079	potassium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015298	solute:cation antiporter activity	IEP	Predicted GO
MF	GO:0015299	solute:proton antiporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015368	calcium:cation antiporter activity	IEP	Predicted GO
MF	GO:0015369	calcium:proton antiporter activity	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015491	cation:cation antiporter activity	IEP	Predicted GO
CC	GO:0015629	actin cytoskeleton	IEP	Predicted GO
BP	GO:0015672	monovalent inorganic cation transport	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
CC	GO:0015935	small ribosomal subunit	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
BP	GO:0016579	protein deubiquitination	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	IEP	Predicted GO
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Predicted GO
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Predicted GO
BP	GO:0016999	antibiotic metabolic process	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
MF	GO:0019783	ubiquitin-like protein-specific protease activity	IEP	Predicted GO
MF	GO:0019829	cation-transporting ATPase activity	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022821	potassium ion antiporter activity	IEP	Predicted GO
MF	GO:0022853	active ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0030003	cellular cation homeostasis	IEP	Predicted GO
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0030029	actin filament-based process	IEP	Predicted GO
BP	GO:0030036	actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0030048	actin filament-based movement	IEP	Predicted GO
CC	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
BP	GO:0030641	regulation of cellular pH	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
MF	GO:0032182	ubiquitin-like protein binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Predicted GO
CC	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0034504	protein localization to nucleus	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0036442	proton-exporting ATPase activity	IEP	Predicted GO
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
MF	GO:0042625	ATPase coupled ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
MF	GO:0043130	ubiquitin binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043248	proteasome assembly	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045257	succinate dehydrogenase complex (ubiquinone)	IEP	Predicted GO
CC	GO:0045281	succinate dehydrogenase complex	IEP	Predicted GO
CC	GO:0045283	fumarate reductase complex	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0045851	pH reduction	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
BP	GO:0051014	actin filament severing	IEP	Predicted GO
MF	GO:0051139	metal ion:proton antiporter activity	IEP	Predicted GO
BP	GO:0051170	import into nucleus	IEP	Predicted GO
BP	GO:0051259	protein complex oligomerization	IEP	Predicted GO
BP	GO:0051262	protein tetramerization	IEP	Predicted GO
BP	GO:0051302	regulation of cell division	IEP	Predicted GO
BP	GO:0051452	intracellular pH reduction	IEP	Predicted GO
BP	GO:0051453	regulation of intracellular pH	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
MF	GO:0051920	peroxiredoxin activity	IEP	Predicted GO
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0060327	cytoplasmic actin-based contraction involved in cell motility	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
BP	GO:0070252	actin-mediated cell contraction	IEP	Predicted GO
BP	GO:0070646	protein modification by small protein removal	IEP	Predicted GO
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0072511	divalent inorganic cation transport	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
CC	GO:0098803	respiratory chain complex	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
MF	GO:0099516	ion antiporter activity	IEP	Predicted GO
MF	GO:0101005	ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1902600	proton transmembrane transport	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001806	Small_GTPase	11	167

External Links

PlasmoDB	810730
PlasmoDB	PF11_0183

PF3D7_1117700 (RAN)

Expression Profile

Co-expression Networks

Functional Annotation