PF3D7_1121300 (TKL2)

Aliases : TKL2

Description : SSF56112: Protein kinase-like domain superfamily. Pfam domain(s): PF07714: Protein tyrosine kinase.

Gene families : OG_01_0002709 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002709_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1121300
Cluster	P. falciparum: Cluster_29

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0927000	TKL2	SSF56112: Protein kinase-like domain superfamily. Pfam...	0.17	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033655	host cell cytoplasm part	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
CC	GO:0044164	host cell cytosol	IDA	PlasmoDB
CC	GO:0044217	other organism part	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003700	DNA-binding transcription factor activity	IEP	Predicted GO
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity	IEP	Predicted GO
MF	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004383	guanylate cyclase activity	IEP	Predicted GO
MF	GO:0005516	calmodulin binding	IEP	Predicted GO
CC	GO:0005658	alpha DNA polymerase:primase complex	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005770	late endosome	IEP	Predicted GO
CC	GO:0005887	integral component of plasma membrane	IEP	Predicted GO
BP	GO:0006182	cGMP biosynthetic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006817	phosphate ion transport	IEP	Predicted GO
BP	GO:0006891	intra-Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006915	apoptotic process	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
BP	GO:0008219	cell death	IEP	Predicted GO
BP	GO:0009657	plastid organization	IEP	Predicted GO
BP	GO:0012501	programmed cell death	IEP	Predicted GO
CC	GO:0015630	microtubule cytoskeleton	IEP	Predicted GO
BP	GO:0015698	inorganic anion transport	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
CC	GO:0017119	Golgi transport complex	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
MF	GO:0043565	sequence-specific DNA binding	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0046068	cGMP metabolic process	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051301	cell division	IEP	Predicted GO
BP	GO:0052652	cyclic purine nucleotide metabolic process	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001245	Ser-Thr/Tyr_kinase_cat_dom	223	493

External Links

PlasmoDB	810767
PlasmoDB	PF11_0220

PF3D7_1121300 (TKL2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation