PF3D7_1124700 (MGE1)

Aliases : MGE1

Description : SSF51064: "GrpE nucleotide exchange factor, head", SSF58014: "GrpE nucleotide exchange factor, coiled-coil". Pfam domain(s): PF01025: GrpE.

Gene families : OG_01_0001125 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001125_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1124700
Cluster	P. falciparum: Cluster_28

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEA	Interproscan predictions
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005759	mitochondrial matrix	ISS	PlasmoDB
BP	GO:0006457	protein folding	IEA	Interproscan predictions
BP	GO:0006457	protein folding	IEA	PlasmoDB
BP	GO:0006810	transport	None	Extended
BP	GO:0006839	mitochondrial transport	None	Extended
BP	GO:0006886	intracellular protein transport	None	Extended
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
BP	GO:0017038	protein import	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0030150	protein import into mitochondrial matrix	ISS	PlasmoDB
MF	GO:0030234	enzyme regulator activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031974	membrane-enclosed lumen	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0033365	protein localization to organelle	None	Extended
BP	GO:0034613	cellular protein localization	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042802	identical protein binding	None	Extended
MF	GO:0042803	protein homodimerization activity	IEA	Interproscan predictions
MF	GO:0042803	protein homodimerization activity	IEA	PlasmoDB
BP	GO:0042886	amide transport	None	Extended
CC	GO:0043233	organelle lumen	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044429	mitochondrial part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0044743	protein transmembrane import into intracellular organelle	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
MF	GO:0046983	protein dimerization activity	None	Extended
MF	GO:0051082	unfolded protein binding	ISS	PlasmoDB
MF	GO:0051087	chaperone binding	IEA	Interproscan predictions
MF	GO:0051087	chaperone binding	IEA	PlasmoDB
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0055085	transmembrane transport	None	Extended
MF	GO:0060589	nucleoside-triphosphatase regulator activity	None	Extended
MF	GO:0060590	ATPase regulator activity	None	Extended
BP	GO:0065002	intracellular protein transmembrane transport	None	Extended
CC	GO:0070013	intracellular organelle lumen	None	Extended
BP	GO:0070585	protein localization to mitochondrion	None	Extended
BP	GO:0070727	cellular macromolecule localization	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
BP	GO:0071806	protein transmembrane transport	None	Extended
BP	GO:0072594	establishment of protein localization to organelle	None	Extended
BP	GO:0072655	establishment of protein localization to mitochondrion	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1990542	mitochondrial transmembrane transport	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0003688	DNA replication origin binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0004152	dihydroorotate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004364	glutathione transferase activity	IEP	Predicted GO
MF	GO:0004588	orotate phosphoribosyltransferase activity	IEP	Predicted GO
MF	GO:0004735	pyrroline-5-carboxylate reductase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005337	nucleoside transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005527	macrolide binding	IEP	Predicted GO
MF	GO:0005528	FK506 binding	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005746	mitochondrial respirasome	IEP	Predicted GO
CC	GO:0005758	mitochondrial intermembrane space	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005853	eukaryotic translation elongation factor 1 complex	IEP	Predicted GO
CC	GO:0005854	nascent polypeptide-associated complex	IEP	Predicted GO
BP	GO:0006206	pyrimidine nucleobase metabolic process	IEP	Predicted GO
BP	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006560	proline metabolic process	IEP	Predicted GO
BP	GO:0006561	proline biosynthetic process	IEP	Predicted GO
BP	GO:0006863	purine nucleobase transport	IEP	Predicted GO
BP	GO:0007005	mitochondrion organization	IEP	Predicted GO
BP	GO:0007006	mitochondrial membrane organization	IEP	Predicted GO
BP	GO:0007007	inner mitochondrial membrane organization	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008169	C-methyltransferase activity	IEP	Predicted GO
MF	GO:0008565	protein transporter activity	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009266	response to temperature stimulus	IEP	Predicted GO
BP	GO:0009304	tRNA transcription	IEP	Predicted GO
MF	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	IEP	Predicted GO
BP	GO:0009408	response to heat	IEP	Predicted GO
BP	GO:0009628	response to abiotic stimulus	IEP	Predicted GO
MF	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015851	nucleobase transport	IEP	Predicted GO
BP	GO:0015858	nucleoside transport	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
MF	GO:0016434	rRNA (cytosine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	IEP	Predicted GO
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Predicted GO
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
BP	GO:0019856	pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predicted GO
CC	GO:0022627	cytosolic small ribosomal subunit	IEP	Predicted GO
MF	GO:0031072	heat shock protein binding	IEP	Predicted GO
CC	GO:0031090	organelle membrane	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
CC	GO:0031970	organelle envelope lumen	IEP	Predicted GO
BP	GO:0032238	adenosine transport	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0042797	tRNA transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
CC	GO:0043657	host cell	IEP	Predicted GO
CC	GO:0044216	other organism cell	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
BP	GO:0045039	protein import into mitochondrial inner membrane	IEP	Predicted GO
BP	GO:0046112	nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
CC	GO:0070469	respirasome	IEP	Predicted GO
BP	GO:0090151	establishment of protein localization to mitochondrial membrane	IEP	Predicted GO
BP	GO:0098781	ncRNA transcription	IEP	Predicted GO
BP	GO:1901264	carbohydrate derivative transport	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000740	GrpE	138	300

External Links

PlasmoDB	810805
PlasmoDB	PF11_0258

PF3D7_1124700 (MGE1)

Expression Profile

Co-expression Networks

Functional Annotation