PF3D7_1127500

Description : SSF52833: Thioredoxin-like superfamily. Pfam domain(s): PF00085: Thioredoxin, PF13848: Thioredoxin-like domain.

Gene families : OG_01_0003787 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0003787_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1127500
Cluster	P. falciparum: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0920900	No alias	SSF52833: Thioredoxin-like superfamily. Pfam domain(s):...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003756	protein disulfide isomerase activity	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005783	endoplasmic reticulum	IEA	PlasmoDB
CC	GO:0005788	endoplasmic reticulum lumen	IEA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0016020	membrane	IEA	PlasmoDB
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016860	intramolecular oxidoreductase activity	None	Extended
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	None	Extended
BP	GO:0019725	cellular homeostasis	None	Extended
CC	GO:0031974	membrane-enclosed lumen	None	Extended
BP	GO:0042592	homeostatic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0043233	organelle lumen	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044432	endoplasmic reticulum part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045454	cell redox homeostasis	IEA	Interproscan predictions
BP	GO:0045454	cell redox homeostasis	IEA	PlasmoDB
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
CC	GO:0070013	intracellular organelle lumen	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000932	P-body	IEP	Predicted GO
MF	GO:0003747	translation release factor activity	IEP	Predicted GO
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEP	Predicted GO
MF	GO:0004392	heme oxygenase (decyclizing) activity	IEP	Predicted GO
MF	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	IEP	Predicted GO
MF	GO:0004601	peroxidase activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0005200	structural constituent of cytoskeleton	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005869	dynactin complex	IEP	Predicted GO
BP	GO:0006099	tricarboxylic acid cycle	IEP	Predicted GO
BP	GO:0006101	citrate metabolic process	IEP	Predicted GO
BP	GO:0006103	2-oxoglutarate metabolic process	IEP	Predicted GO
BP	GO:0006108	malate metabolic process	IEP	Predicted GO
BP	GO:0006166	purine ribonucleoside salvage	IEP	Predicted GO
BP	GO:0006190	inosine salvage	IEP	Predicted GO
BP	GO:0006402	mRNA catabolic process	IEP	Predicted GO
BP	GO:0006415	translational termination	IEP	Predicted GO
BP	GO:0006787	porphyrin-containing compound catabolic process	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006979	response to oxidative stress	IEP	Predicted GO
BP	GO:0008064	regulation of actin polymerization or depolymerization	IEP	Predicted GO
MF	GO:0008079	translation termination factor activity	IEP	Predicted GO
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Predicted GO
MF	GO:0008252	nucleotidase activity	IEP	Predicted GO
MF	GO:0008253	5'-nucleotidase activity	IEP	Predicted GO
CC	GO:0008290	F-actin capping protein complex	IEP	Predicted GO
MF	GO:0008375	acetylglucosaminyltransferase activity	IEP	Predicted GO
MF	GO:0008379	thioredoxin peroxidase activity	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
BP	GO:0010639	negative regulation of organelle organization	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016615	malate dehydrogenase activity	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Predicted GO
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Predicted GO
BP	GO:0016999	antibiotic metabolic process	IEP	Predicted GO
MF	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	IEP	Predicted GO
BP	GO:0019430	removal of superoxide radicals	IEP	Predicted GO
BP	GO:0019439	aromatic compound catabolic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
MF	GO:0030060	L-malate dehydrogenase activity	IEP	Predicted GO
BP	GO:0030832	regulation of actin filament length	IEP	Predicted GO
BP	GO:0030833	regulation of actin filament polymerization	IEP	Predicted GO
BP	GO:0030834	regulation of actin filament depolymerization	IEP	Predicted GO
BP	GO:0030835	negative regulation of actin filament depolymerization	IEP	Predicted GO
BP	GO:0030837	negative regulation of actin filament polymerization	IEP	Predicted GO
CC	GO:0030904	retromer complex	IEP	Predicted GO
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Predicted GO
BP	GO:0031333	negative regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0032271	regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032272	negative regulation of protein polymerization	IEP	Predicted GO
BP	GO:0032535	regulation of cellular component size	IEP	Predicted GO
BP	GO:0032956	regulation of actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0032970	regulation of actin filament-based process	IEP	Predicted GO
BP	GO:0033015	tetrapyrrole catabolic process	IEP	Predicted GO
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0034655	nucleobase-containing compound catabolic process	IEP	Predicted GO
CC	GO:0035770	ribonucleoprotein granule	IEP	Predicted GO
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
BP	GO:0042167	heme catabolic process	IEP	Predicted GO
BP	GO:0042278	purine nucleoside metabolic process	IEP	Predicted GO
BP	GO:0042451	purine nucleoside biosynthetic process	IEP	Predicted GO
MF	GO:0043021	ribonucleoprotein complex binding	IEP	Predicted GO
MF	GO:0043022	ribosome binding	IEP	Predicted GO
BP	GO:0043094	cellular metabolic compound salvage	IEP	Predicted GO
BP	GO:0043101	purine-containing compound salvage	IEP	Predicted GO
BP	GO:0043174	nucleoside salvage	IEP	Predicted GO
CC	GO:0043186	P granule	IEP	Predicted GO
BP	GO:0043242	negative regulation of protein complex disassembly	IEP	Predicted GO
BP	GO:0043244	regulation of protein complex disassembly	IEP	Predicted GO
BP	GO:0043254	regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0043624	cellular protein complex disassembly	IEP	Predicted GO
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0044087	regulation of cellular component biogenesis	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044270	cellular nitrogen compound catabolic process	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
MF	GO:0044877	protein-containing complex binding	IEP	Predicted GO
BP	GO:0046102	inosine metabolic process	IEP	Predicted GO
BP	GO:0046103	inosine biosynthetic process	IEP	Predicted GO
BP	GO:0046128	purine ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0046129	purine ribonucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0046149	pigment catabolic process	IEP	Predicted GO
BP	GO:0046700	heterocycle catabolic process	IEP	Predicted GO
BP	GO:0048519	negative regulation of biological process	IEP	Predicted GO
MF	GO:0050483	IMP 5'-nucleotidase activity	IEP	Predicted GO
MF	GO:0051015	actin filament binding	IEP	Predicted GO
BP	GO:0051016	barbed-end actin filament capping	IEP	Predicted GO
BP	GO:0051129	negative regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051187	cofactor catabolic process	IEP	Predicted GO
BP	GO:0051493	regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0051494	negative regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0051693	actin filament capping	IEP	Predicted GO
MF	GO:0051920	peroxiredoxin activity	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
BP	GO:0090066	regulation of anatomical structure size	IEP	Predicted GO
BP	GO:0098754	detoxification	IEP	Predicted GO
BP	GO:0098869	cellular oxidant detoxification	IEP	Predicted GO
BP	GO:0110053	regulation of actin filament organization	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Predicted GO
BP	GO:1901361	organic cyclic compound catabolic process	IEP	Predicted GO
BP	GO:1901879	regulation of protein depolymerization	IEP	Predicted GO
BP	GO:1901880	negative regulation of protein depolymerization	IEP	Predicted GO
BP	GO:1902903	regulation of supramolecular fiber organization	IEP	Predicted GO
BP	GO:1902904	negative regulation of supramolecular fiber organization	IEP	Predicted GO
BP	GO:1990748	cellular detoxification	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013766	Thioredoxin_domain	34	134

External Links

PlasmoDB	810833
PlasmoDB	PF11_0286

PF3D7_1127500

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation